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| 1 | 深水砂体成因研究新进展显示文摘在深水重力流研究中,传统浊流理论正受到砂质块体搬运和底流再改造砂体概念的冲击。陆架边缘沉积物滑塌是重力流驱动沉积过程最普遍的诱因,块体搬运过程(包含滑动、滑塌以及碎屑流)由于具有较高沉积物浓度(体积分数为25%~100%),表现为弹性和塑性特征。浊流因具有较低的沉积物浓度(体积分数为1%~23%)表现为黏性流动,不属于块体搬运的范畴。除重力流外,底流也是重要的深海搬运沉积方式。4种最常见的底流分别为:温盐流、风力驱动底流、深海潮汐及斜压流,牵引构造可用来区分这4种底流形成的再改造砂体,其中内波和内潮汐引起的斜压流再改造砂体的特征仍需深入研究。仅通过地震剖面与地质体形态无法识别块体搬运和底流再改造砂体类型,岩心和露头观察是唯一能鉴别其沉积相特征的方法。短期事件,如地震、海啸、热带风暴等,可能只持续几小时或者几天,却是沉积物滑塌的重要触发机制,比长达数千年低水位沉积期更为重要。 | Shanmugam G | 2013 | 石油勘探与开发2013，40，3： | 111 |
| 2 | Relationship between T-lymphocyte cytokine levels and sero-response to hepatitis B vaccines显示文摘AIM: To investigate the cellular defects by analyzing the (Th1/Th2) cytokine levels in vaccine responders and non-responders. METHODS: Peripheral blood mononuclear cell (PBMC) from responders and non-responders were stimulated with or with out recombinant HBsAg or PHA. Broad spectrum of cytokines viz (Th1) IFN-γ, IL-2, TNF-α, IL-12 and (Th2) IL-10, IL-4 were measured after in vitro stimulation with recombinant HBsAg and were compared with respective antibody titers. RESULTS: A significant decrease (P = 0.001) in Th1 and Th2 cytokines namely, IL-2, INF-γ, TNF-α and IL-10in non-responders was observed. The level of IL-4 was not significant between the three groups. Furthermore, despite a strong Th1 and Th2 cytokine response, the level of IL-12 was elevated in high-responders compared to other groups (P = 0.001) and demonstrated a positive correlation with anti-HBs titers and Th1 cytokine response. CONCLUSION: Our findings suggest that unrespon-siveness to recombinant hepatitis B vaccines (rHB) is multifactorial, including specific failure of antigen presentation or the lack of both T helper Th1 and Th2 response. | Vijayakumar Velu Shanmugam Saravanan Subhadra Nandakumar Esaki Muthu Shankar Appasamy Vengatesan Suresh Sakharam Jadhav Prasad Suryakant Kulkarni Sadras Panchatcharam Thyagarajan | 2008 | World Journal of Gastroenterology2008，14，22： | 22 |
| 3 | An overview of PCI in the very elderly显示文摘心血管的疾病,和特别地 ischemic 心疾病(IHD ) ,是病态和死亡的一个主要原因在老(>80 年) 世界范围。这些病人代表为经皮的冠的干预(一种总线标准) 介绍的一个很快成长的队,现在在五个病人组成超过一在真实世界的实践与一种总线标准对待。而且,他们经常比他们的更年轻的对应物有更大的 ischemic 负担,建议他们有从冠的 revascularization 治疗的利益的更大的范围。尽管有这,老在那里在临床的 revascularization 试用并且历史上经常是未被充分代表的是在为一种总线标准过程提交他们的医生勉强的度与令人失望的结果的感觉,低成功和高复杂并发症评价。几个问题贡献了这,包括为有晚介绍的 IHD 的更老的病人的趋势,与不正常的症状或关于他们的程序的 risk-to-benefit 比率的非诊断的 ECG,和保留由于更短的预期寿命,从 antiplatelet 和 anticoagulation 药的 comorbidities 和增加的流血风险的存在。然而,在在过去的十年的一种总线标准技术和技术的进展导致了更好的结果和复杂并发症和存在身体的更低的风险证据现在显示那老实际上比更年轻的人口从一种总线标准导出更相对的利益。重要地,这适用于所有一种总线标准背景:选任,迫切并且紧急情况。这评论在与长期的稳定的 IHD 的老介绍讨论一种总线标准的角色,非圣举起急性冠的症候群,和圣举起心肌的梗塞。当认为在为研究和开发的这个队和进行中的需要的一种总线标准进一步在这些挑战性的病人改进结果时,它也探讨遇见的临床的挑战。 | Vimalraj Bogana Shanmugam Richard Harper Ian Meredith Yuvaraj Malaiapan Peter J Psaltis | 2015 | Journal of Geriatric Cardiology2015，12，2： | 22 |
| 4 | 等深流沉积:物理海洋学、过程沉积学和石油地质学显示文摘主要阐述与等深流沉积以及其他底流沉积相关的基本原理。深海底流分为温盐引起的自转型等深流、风力驱动底流、潮汐驱动底流(大多在海底峡谷)、内波/内潮汐驱动的斜压流4种基本类型,均常见牵引构造。等深流沉积是温盐引起的自转型等深流沉积体,粒级可为泥级或细砂级,含硅质或钙质碎屑。在古代等深流与其他等深流的区分方面,目前尚无沉积学或地震学诊断标准。在岩心和露头上,双黏土层是识别深海潮汐沉积的可靠指标。加的斯湾虽然是泥质等深流沉积相模式的代表,但并无真正的等深流沉积,仅受与地中海流出水(MOW)有关的短暂等深流影响,并受内波和内潮汐、浊流、海啸、飓风、泥火山、煤成气渗漏、沉积物供给、孔隙水排出和海底地形等其他复杂因素的影响。在加的斯湾综合大洋钻探(IODP)339项目岩心中没有发现能用于解释沉积过程的原生沉积构造,因此等深流沉积相模式应予废弃。4类底流改造砂体均具备成为油气储集层的潜力。在佛罗里达海峡大巴哈马浅滩(Great Bahama Bank)附近的等深流沉积,因为其中的泥质成分被强烈的等深流从粒间原生孔隙中簸选出来,最大测量孔隙度为40%,最大渗透率达9 881×10^(-3)μm^2。现代等深流的实证数据也显示其具有发育盖层和烃源岩的潜力。因此,未来石油勘探与开发应重点关注这些经常被忽视的深海硅质和钙质碎屑等深流沉积储集层。 | SHANMUGAM G | 2017 | 石油勘探与开发2017，44，2： | 15 |
| 5 | Inguinodynia following Lichtenstein tension-free hernia repair:A review显示文摘Chronic Groin Pain (Inguinodynia) following inguinal hernia repair is a significant,though under-reported problem. Mild pain lasting for a few days is common following mesh inguinal hernia repair. However,moderate to severe pain persisting more than 3 mo after inguinal herniorrhaphy should be considered as pathological. The major reasons for chronic groin pain have been identified as neuropathic cause due to inguinal nerve(s) damage or non-neuropathic cause due to mesh or other related factors. The symptom complex of chronic groin pain varies from a dull ache to sharp shooting pain along the distribution of inguinal nerves. Thorough history and meticulous clinical examination should be performed to identify the exact cause of chronic groin pain,as there is no single test to confirm the aetiology behind the pain or to point out the exact nerve involved. Various studies have been performed to look at the difference in chronic groin pain rates with the use of mesh vs non-mesh repair,use of heavyweight vs lightweight mesh and mesh fixation with sutures vs glue. Though there is no convincing evidence favouring one over the other,lightweight meshes are generally preferred because of their lesser foreign body reaction and better tolerance by the patients. Identification of all three nerves has been shown to be an important factor in reducing chronic groin pain,though there are no well conducted randomised studies to recommend the benefits of nerve excision vs preservation. Both nonsurgical and surgical options have been tried for chronic groin pain,with their consequent risks of analgesic sideeffects,recurrent pain,recurrent hernia and significant sensory loss. By far the best treatment for chronic groin pain is to avoid bestowing this on the patient by careful intra-operative handling of inguinal structures and better patient counselling pre-and post-herniorraphy. | Abdul Hakeem Venkatesh Shanmugam | 2011 | World Journal of Gastroenterology2011，17，14： | 13 |
| 6 | Coinfection of hepatitis B and hepatitis C virus in HIV-infectedpatients in south India显示文摘AIM: To screen for the co-infection of hepatitis B (HBV) and hepatitis C virus (HCV) in human immunodeficiency virus (HIV) infected patients in southern India. METHODS: Five hundred consecutive HIV infected patients were screened for Hepatitis B Virus (HBsAg and HBV-DNA) and Hepatitis C virus (anti-HCV and HCV-RNA) using commercially available ELISA kits; HBsAg, HBeAg/ anti-HBe (Biorad laboratories, USA) and anti-HCV (Murex Diagnostics, UK). The HBV-DNA PCR was performed to detect the surface antigen region (pre S-S). HCV-RNA was detected by RT-PCR for the detection of the constant 5' putative non-coding region of HCV. RESULTS: HBV co-infection was detected in 45/500 (9%) patients and HCV co-infection in 11/500 (2.2%) subjects. Among the 45 co-infected patients only 40 patients could be studied, where the detection rates of HBe was 55% (22/40), antiHBe was 45% (18/40) and HBV-DNA was 56% (23/40). Among 11 HCV co-infected subjects, 6 (54.5%) were anti-HCV and HCV RNA positive, while 3 (27.2%) were positive for anti-HCV alone and 2 (18%) were positive for HCV RNA alone. CONCLUSION: Since the principal routes for HIV transmission are similar to that followed by the hepatotropic viruses, as a consequence, infections with HBV and HCV are expected in HIV infected patients. Therefore, it would be advisable to screen for these viruses in all the HIV infected individuals and their sexual partners at the earliest. | Shanmugam Saravanan Vijayakumar Velu Nagalingeswaran Kumarasamy Subhadra Nandakumar Kailapuri Gangatharan Murugavel Pachamuthu Balakrishnan Solomon Suniti Sadras Panchatcharam Thyagarajan | 2007 | World Journal of Gastroenterology2007，13，37： | 6 |
| 7 | Antioxidant and hepatoprotective effects of Hypsizygus ulmarius polysaccharide on alcoholic liver injury in rats显示文摘Hypsizygus ulmarius polysaccharide(HUP)is a water-soluble polysaccharide obtained by hot water extraction,followed by precipitation and deproteinization.The characteristics of HUP,antioxidant activity and liver protection against alcohol-induced liver damage were studied.Structural characteristics indicate that the HUP is a pyran-type polysaccharide with a molecular weight of 2076 Da.In antioxidant scavenging assay,HUP showed moderate DMPD radical scavenging activity,cupric ion reducing antioxidant capacity and inhibitory effect against lipid peroxidation in a dose-dependent manner.Regarding in vivo hepatoprotective activity,compared with the ethanol induction group,pre-treatment of low and high doses of HUP signifi cantly reduced the behaviours of serum enzymes,lowered the levels of hepatic oxidative stress markers,restored the levels of biochemical constituents,enhanced the levels of liver and serum enzymatic antioxidants and non-enzymatic antioxidants,and improved the serum lipid levels of alcohol-intoxicated rats.The hepatoprotective effect of HUP was comparable to positive control silymarin.Besides,HUP pre-treatment signifi cantly normalized the histopathological changes induced by ethanol.The results indicate that HUP could be used as a functional food and may protect the biological system from oxidative stress through its antioxidant activity,thus having a signifi cant protective effect on acute alcoholic liver injury. | Sudha Govindan Angu Jayabal Jayasakthi Shanmugam Prasanna Ramani | 2021 | Food Science and Human Wellness2021，10，4： | 6 |
| 8 | In vitro antioxidant,antimicrobial and anti-diabetic properties of polyphenols of Passiflora ligularis Juss.fruit pulp显示文摘In the present study,anti-radical,anti-diabetic and antimicrobial activities of different solvent extracts of Passiflora ligularis fruits were investigated.Among the various solvents,acetone extract displayed maximum total phenolic(640.70 mg GAE/g extract),tannin(214.30 mg GAE/g extract)and flavonoid contents(387.33 mg RE/g extract).Results of antioxidant studies revealed that the acetone extract of fruits possessed an efficient 2,2-diphenyl-1-picryl-hydrazyl(DPPH•)(IC5019.13g/mL),2,2-azinobis(3-ethylbenzothiozoline-6-sulfonic acid)(ABTS•+)(9800.94mol/L trolox equi/g extract),superoxide(78.27%)and nitric oxide(79.95%)radical scavenging activities,ferric reducing antioxidant power(43.06 mmol Fe(II)/mg extract),metal chelating(134.53 mg EDTA/g extract)ability.The acetone extract of P.ligularis fruits also exhibited significant(P<0.005)inhibition activities onα-amylase(82.56%)andα-glucosidase(75.36%)enzymes.Furthermore,the fruits of P.ligularis also demonstrated antibacterial activities against Gram(+)and Gram(−)bacteria and inhibited the fungal strains Candida albicans(14.85 mm)and Aspergillus niger(13.91 mm)in the disc diffusion method.Quantification of polyphenolics by HPLC showed the presence of ellagic acid,gallic acid,and rutin.Therefore,the results indicate that the fruit pulp of P.ligularis can serve as a potential antioxidative and antimicrobial agent in food and pharmaceutical industries. | Shanmugam Saravanan Thangaraj Parimelazhagan | 2014 | Food Science and Human Wellness2014，3，2： | 6 |
| 9 | Characterization of free carbon in the as-thermolyzed Si-B-C-N ceramic from a polyorganoborosilazane precursor显示文摘Polyorganoborosilazane((B[C_(2)H_(4)-Si(CH_(3))NH]_(3))n)was synthesized via monomer route from a single-source precursor and thermolyzed at 1300℃in argon atmosphere.The as-thermolyzed Si-B-C-N ceramic was characterized using X-ray diffraction(XRD)and Raman spectroscopy.The crystallization behavior of silicon carbide in the as-thermolyzed amorphous Si-B-C-N matrix was understood by XRD studies,and the crystallite size calculated using Scherrer equation was found to increase from 2 nm to 8 nm with increase in dwelling time.Concomitantly,Raman spectroscopy was used to characterize the free carbon present in the as-thermolyzed ceramic.The peak positions,intensities and full width at half maximum(FWHM)of D and G bands in the Raman spectra were used to study and understand the structural disorder of the free carbon.The G peak shift towards 1600 cm-1 indicated the decrease in cluster size of the free carbon.The cluster diameter of the free carbon calculated using TK(Tuinstra and Koenl)equation was found to decrease from 6.2 nm to 5.4 nm with increase in dwelling time,indicating increase in structural disorder. | Adhimoolam Bakthavachalam KOUSAALYA Ravi KUMARa Shanmugam PACKIRISAMY | 2013 | Journal of Advanced Ceramics2013，2，4： | 5 |
| 10 | 密度羽流构型特征、控制因素及其对深水沉积的启示--对河口和其他环境中密度羽流进行的全球卫星调查显示文摘基于对美国国家航空和航天局(NASA)数千幅卫星图像的系统汇编,对45个密度羽流(包含21条主要河流和6种不同的沉积环境)进行实例分析,首次揭示现代环境中各种密度羽流自然构型变化特征,指出密度羽流至少有24种构型。研究发现密度羽流受多达18种包括海洋、气象和其他复杂因素控制:(1)中国黄河受到潮汐和河道变化的影响;(2)中国长江在冬季受陆架潮流和潮汐垂直混合的影响;(3)阿根廷和乌拉圭里约热内卢的拉普拉塔河口受洋流控制;(4)美国加利福尼亚州旧金山湾受潮流影响;(5)印度洋马纳尔湾受季风环流影响;(6)埃及红海受风成尘埃影响;(7)美国大西洋边缘受飓风气旋影响;(8)斯里兰卡受海啸影响;(9)阿拉斯加柯柏河受高坡辫状河三角洲的影响;(10)伊利湖受湖震影响;(11)纳米比亚大陆边缘受上升涌流影响;(12)白令海受浮游生物的影响;(13)大西洋大巴哈马海岸受鱼类活动影响;(14)印度尼西亚受火山活动影响;(15)格陵兰岛受冰川融化的影响;(16)南太平洋受珊瑚礁的影响;(17)卡罗莱纳州大陆凸起受地形坑洼的影响;(18)日本大槌湾受内部狂浪控制。河流-洪水成因的异重流以泥质为主,且往往出现在内陆架靠近海岸线的沉积环境中;从成因机制上讲,异重流无法通过陆架把砂砾输送到深海;此外,野外观察表明这类异重流不能在深水环境中形成米级厚度的砂层。因此,河流-洪水触发的异重岩不可能成为深水沉积储集层,除非另有证据。 | SHANMUGAM G | 2018 | 石油勘探与开发2018，45，4： | 5 |
| 11 | Effect of Autogenous Arc Welding Processes on Tensile and Impact Properties of Ferritic Stainless Steel Joints显示文摘The effect of autogeneous arc welding processes on tensile and impact properties of ferritic stainless steel conformed to AISI 409M grade is studied.Roiled plates of 4 mm thickness have been used as the base material for preparing single pass butt welded joints.Tensile and impact properties,microhardness,microstructure,and fracture surface morphology of continuous current gas tungsten arc welding (CCGTAW),pulsed current gas tungsten arc welding (PCGTAW),and plasma arc welding (PAW) joints are evaluated and the results are compared.It is found that the PAW joints of ferritic stainless steel show superior tensile and impact properties when compared with CCG- TAW and PCGTAW joints,and this is mainly due to lower heat input,finer fusion zone grain diameter,and higher fusion zone hardness. | A K Lakshminarayanan K Shanmugam V Balasubramanian | 2009 | Journal of Iron and Steel Research(International)2009，16，1： | 5 |
| 12 | Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers显示文摘OBJECTIVE Platinum compounds such as cisplatin and carboplatin are frequently used as the first-line chemotherapy for the treatment of the head and neck squamous cell carcinoma(HNSCC).In the present study,we investigated whether garcinol,apolyisoprenylated benzophenone can chemosensitize HNSCC to cisplatin.METHODS The effect of garcinol and cisplatin on HNSCC was assessed by MTT,Western blotting,real time PCR,FACS,immunohistochemistry,DNA binding assay and xenograft mouse model.RESULTS We found that garcinol inhibited the viability of a panel of diverse HNSCC cell lines,enhanced the apoptotic effect of cisplatin,suppressed constitutive as well as cisplatin-induced NF-κB activation,and downregulated the expression of various oncogenic gene products(cyclin D1,Bcl-2,survivin and VEGF).In vivo study showed that administration of garcinol alone(0.5 mg·kg-1,ip five times/week)significantly suppressed the growth of the tumor,and this effect was further increased by cisplatin.Both the markers of proliferation index(Ki-67)and microvessel density(CD31)were downregulated in tumor tissues by the combination of cisplatin and garcinol.The pharmacokinetic results of garcinol indicated that good systemic exposure was achievable after ip administration of garcinol at 0.5and 2mg·kg-1 with mean peak concentration(cmax)of 1825.4 and 6635.7nmol·L-1 in the mouse serum,respectively.CONCLUSION Overall,our results suggest that garcinol can indeed potentiate the effects of cisplatin by negative regulation of various inflammatory and proliferative biomarkers. | Feng Li Muthu K. Shanmugam Kodappully Sivaraman Siveen Fan Wang Tina H. Ong Ser Yue Loo Mahadeva M.M. Swamy Somnath Mandal Alan Prem Kumar Boon Cher Goh Tapas Kundu Kwang Seok Ahn Ling Zhi Wang Kam Man Hui Gautam Sethi | 2015 | 中国药理学与毒理学杂志2015，29，S1： | 4 |
| 13 | Tensile and Impact Properties of Shielded Metal Arc Welded AISI 409M Ferritic Stainless Steel Joints显示文摘The present study is concerned with the effect of filler metals such as austenitic stainless steel, ferritic stainless steel and duplex stainless steel on tensile and impact properties of the ferritic stainless steel conforming to AISI 409M grade. Rolled plates of 4 mm thickness were used as the base material for preparing single pass butt welded joints. Tensile and impact properties, microhardness, microstructure and fracture surface morphology of the joints fabricated by austenitic stainless steel, ferritic stainless steel and duplex stainless steel filler metals were evaluated and the results were reported. From this investigation, it is found that the joints fabricated by duplex stainless steel filler metal showed higher tensile strength and hardness compared to the joints fabricated by austenitic and ferritic stainless steel filler metals. Joints fabricated by austenitic stainless steel filler metal exhibited higher ductility and impact toughness compared with the joints fabricated by ferritic stainless steel and duplex stainless steel filler metals. | K. Shanmugam A.K. Lakshminarayanan V. Balasubramanian | 2009 | Journal of Materials Science & Technology2009，25，2： | 4 |
| 14 | Comparison of three different recombinant hepatitis B vaccines:GeneVac-B,Engerix B and Shanvac B in high risk infants born to HBsAg positive mothers in India显示文摘AIM: To evaluate a low cost Indian recombinant hepatitis B vaccine GeneVac-B for its immunogenicity and safety in comparison to Engerix B and Shanvac B vaccine in high risk newborn infants born to hepatitis B surface antigen (HBsAg) positive mothers. METHODS: A total of 158 infants were enrolled in the study. Fifty eight infants were enrolled in the GeneVac-B group while 50 each were included for Engerix B and Shanvac B groups. A three-dose regimen of vaccination; at birth (within 24 h of birth), 1st mo and 6 mo. were adopted with 10 μg dosage administered uniformly in all the three groups. Clinical and immunological parameters were assessed for safety and immunogenicity of the vaccines, in all the enrolled infants. RESULTS: Successful follow up until seven months of age was achieved in 83/ (48/58) for GeneVac-B, 76/ (38/50) and 64/ (32/50) for Engerix B and Shanvac B groups respectively. 100/ seroconversion and seroprotection was achieved in all the three groups of infants. The geometric mean titers of anti-HBs one month after the completion of three dose of vaccination were 90.5, 80.9 and 72.5 mIU/mL in GeneVac-B, Engerix B and Shanvac B vaccine group respectively. Furthermore the level of anti-HBs increases with age ofbabies who were born to HBsAg positive mothers. The GMT values of anti-HBs were 226.7, 193.9 and 173.6 mIU/mL respectively in GeneVac-B, Engerix B and Shanvac B groups one year after the completion of the three doses of vaccine. No systemic reactions were reported in infants during the entire vaccination process of GeneVac-B and the other two vaccines. Clinical safety parameters remained within the normal limits throughout the study period.CONCLUSION: The study concludes that there is no significant difference between the three recombinant hepatitis B vaccines. Administration of these vaccines within 24 h of birth to babies, born to HBsAg positive mothers will reduce the incidence of HBV infection. | Vijayakumar Velu Subhadra Nandakumar Saravanan Shanmugam Suresh Sakharam Jadhav Prasad Suryakant Kulkarni Sadras Panchatcharam Thyagarajan | 2007 | World Journal of Gastroenterology2007，13，22： | 4 |
| 15 | A comprehensive review of significant researches on content based indexing and retrieval of visual information显示文摘 | R. PRIYA T. N. SHANMUGAM | 2013 | Frontiers of Computer Science2013，7，5： | 3 |
| 16 | Synergism between natural products and antibiotics against infectious diseases显示文摘 | Shanmugam Hemaiswarya Anil Kumar Kruthiventi Mukesh Doble | 2008 | Phytomedicine2008，，8： | 3 |
| 17 | Bleeding outcomes after non-emergency percutaneous coronary intervention in the very elderly显示文摘BackgroundOctogenarians 组成病人为经皮的冠的干预(一种总线标准).MethodsThis 学习评估了的非紧急情况介绍的一个增加的比例在里面医院程序的特征和结果,包括为非紧急情况一种总线标准在 2010 年 1 月和 2012 年 12 月之间介绍给单个大体积的 293 octogenarians 的流血事件第三级的照顾澳大利亚人中心。比较被做, 293 个连续病人,其损害与心肌的梗塞是的 octogenarians.ResultsNon 圣举起被匹配小于等于 60 年变老为在 octogenarians 的非紧急情况一种总线标准的最经常的指示。比作更年轻的队,他们有合作病态和更复杂的冠的疾病的更高的流行,包括更多的类型 C 和钙化的损害。低分子的重量肝磷脂的仙子程序的使用(LMWH;1.0% 对 5.8% ;P < 0.001 ) 并且 glycoprotein IIb/IIIa 禁止者(2.1% 对 9.6% ;P < 0.001 ) 更低,当大腿骨的动脉的存取比在更年轻的病人更通常被使用时(80.9% 对 67.6% ;P < 0.001 ) 。总的来说,向所有流血事件在的更高的发生有一个不重要的趋势老(9.2% 对 5.8% ;P = 0.12 ) 。在存取地点或非存取地点流血和专业或在二个队之间的次要的流血没有重要差别。亚分析没在由 LMWH, glycoprotein IIb/IIIa 禁止者或大腿骨的动脉的存取的使用为率放血上揭示任何重要影响。另外,处于在二 groups.ConclusionsIn 之间的在里面医院死亡,击或尖锐 stent 血栓的率没有重要差别这单个中心研究,我们没包括在经历非紧急情况一种总线标准的 octogenarians 流血的发生在不利在里面医院结果观察重要增加。 | Vimalraj Bogana Shanmugam Dennis T Wong Hashrul Rashid James D Cameron Yuvaraj Malaiapan Peter J Psaltis | 2017 | Journal of Geriatric Cardiology2017，14，10： | 3 |
| 18 | Current trends in the diagnosis and management of post-herniorraphy chronic groin pain显示文摘Inguinodynia(chronic groin pain) is one of the recognised complications of the commonly performed Lichtenstein mesh inguinal hernia repair.This has major impact on quality of life in a significant proportion of patients.The pain is classif ied as neuropathic and nonneuropathic related to nerve damage and to the mesh,respectively.Correct diagnosis of this problem is relatively difficult.A thorough history and clinical examination are essential,as is a good knowledge of the groin nerve distribution.In spite of the common nature of the problem,the literature evidence is limited.In this paper we discuss the diagnostic tools and treatment options,both non-surgical and surgical.In addition,we discuss the criteria for surgical intervention and its optimal timing. | Abdul Hakeem Venkatesh Shanmugam | 2011 | World Journal of Gastrointestinal Surgery2011，3，6： | 3 |
| 19 | Novel en-bloc resection of locally advanced hilar cholangiocarcinoma: the Rex recess approach显示文摘Loco-regional recurrence after potentially curative resection remains a problem in hilar cholangiocarcinoma. Hilar dissection risks local spillage of tumor cells leading to suboptimal disease free survival. We have developed a new technique of radical resection for hilar cholangiocarcinoma based on the distinctive anatomy of the Rex recess of the liver, which has been assessed in two patients with locally advanced hilar cholangiocarcinoma. This technique included a right hepatectomy with en-bloc resection of the hepatoduodenal ligament and portal venous reconstruction to the left portal vein at the Rex recess. Both patients had R0 resection and have been disease-free for 26 and 38 months, respectively. | Mohamed Rela Rajesh Rajalingam Vivekanandan Shanmugam Adrian O' Sullivan Mettu S Reddy Nigel Heaton | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，1： | 3 |
| 20 | Effect of cooling rate on the microstructure and mechanical properties of Nb-microalloyed steels显示文摘 | S. Shanmugam N.K. Ramisetti R.D.K. Misra T. Mannering D. Panda S. Jansto | 2007 | Materials Science & Engineering A2007，，： | 2 |
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