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| 1 | Effect of chemical phosphorylation on solubility of buffalo milk proteins显示文摘 | NAYAK S ARORA S SINDHU J | 2006 | International Dairy Journal2006，16，3： | 1 |
| 2 | Peripheral blood cytotoxic gamma delta T lymphocytes from patients with human immunodeficiency virus type1and AIDS lyse uninfected CD4+T cells,and their cytocidal potential correlates with viral load显示文摘 | Sindhu ST Ahmad R Morisset R Ahmad A Menezes J | 2003 | J Virol2003，77，3： | 1 |
| 3 | A high- fat, refine&carbohydrate diet induces endothelial dys- function and oxidant/antioxidant imbalance and depres- ses NOS protein expression显示文摘 | Roberts C K Barnard R J Sindhu R K | 2005 | J Appl Physiol2005，98，1： | 1 |
| 4 | GPU-based normalized cuts for road extraction using satellite imagery显示文摘 | SENTHILNATH J SINDHU S OMKAR S N | 2014 | Journal of Earth System Science2014，123，8： | 1 |
| 5 | HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing显示文摘 | Richard J Sindhu S Pham TNQ | 2010 | Blood2010，115，7： | 1 |
| 6 | Microbial synthesis of poly-3-hydroxybutyrate and its application as targeted drug delivery vehicle显示文摘 | Althuri A Mathew J Sindhu R | 2013 | Bioresour Technol2013，145，： | 1 |
| 7 | Effect of chemical phosphorylation on solubility of buffalo milk proteins显示文摘 | NAYAK S K ARORA S SINDHU J S | 2006 | Inter- national Dairy Journal2006，16，3： | 1 |
| 8 | Effect of chemical phosphorylation on solubility of buffalo milk proteins显示文摘 | Nayak S K Arora S Sindhu J S | 2006 | International Dairy Journal2006，16，： | 1 |
| 9 | Lignocellulosic ethanol in India: prospects, challenges and feedstock availability 显示文摘 | SUKUMARAN R K SURENDER V J SINDHU R | 2010 | Bioresource Technology2010，101，13： | 1 |
| 10 | Oxidative stress and dysregulation of NAD(P) H oxidase and antioxidant enzymes in diet- induced metabolic syndrome 显示文摘 | Roberts CK Barnard R J Sindhu RK | 2006 | Metabolism2006，55，7： | 1 |
| 11 | Influence of sodium phosphate on the heat stability of buffalo milk and its concentrate显示文摘 | SINDHU J S | 1985 | Journal of Food Processing and Preservation1985，9，2： | 1 |
| 12 | Effect of chemical phosphorylation on solubility of buffalo milk proteins显示文摘 | NAYAK S K ARORA S SINDHU J S | 2006 | International Dairy Journal2006，，6： | 1 |
| 13 | Effect of chemical phosphorylation on solubility of buffalo milk proteins显示文摘 | ARORA Sumit Sindhu J S | 2006 | International Dairy Journal2006，16，3： | 1 |
| 14 | Effect of chemical phosphorylation on solubility of buffalo milk proteins显示文摘 | Nayak S K Sumit A Sindhu J S | 2006 | International Dairy Journal2006，16，3： | 1 |
| 15 | Effect of antimony substitution on structural and electrical properties of LaFeO3 显示文摘 | Berchmans L J Sindhu R Angappan S | 2008 | Journal of Materials Processing Technology2008，207，13： | 1 |
| 16 | A clinically relevant combination treatment with doxorubicin and cyclophosphamide does not induce hepatotoxicity in C57BL/6J mice显示文摘Background and aims:Chronic exposure to chemotherapeutics can lead to severe adverse events including hepatotoxicity.A combination chemotherapy regimen of doxorubicin(DOX)and cyclophos-phamide(CPS)is employed in treatment of several cancers such as leukemia,lymphoma,and breast cancer.It is not well understood whether a combination therapy with DOX and CPS can induce hepa-totoxicity.We therefore sought to determine whether co-administration of DOX and CPS at their clini-cally relevant doses and frequency results in hepatotoxicity.Methods:Male C57BL/6J mice received one intraperitoneal injection of saline or DOX-2 mg/kg and CPS-50 mg/kg once a week for 4 weeks.After the treatment period,liver histology and various serum bio-markers of hepatotoxicity were assessed.Results:Co-treatment with DOX and CPS did not alter the serum levels of alanine aminotransferase(ALT),alkaline phosphatase(ALP),bilirubin,albumin,globulin,or total protein.Similarly,co-administration of DOX and CPS did not result in a noticeable change in liver histology.However,it was notable that the concomitant treatment with DOX and CPS resulted in a significant increase in serum levels of aspartate aminotransferase(AST).Elevated serum AST levels were also associated with increased serum creatinine kinase(CK)levels,suggesting that the elevated serum AST levels are likely due to muscle injury following the co-administration of DOX and CPS.Conclusions:Taken together,our results,for the first time,suggest that co-administration of DOX and CPS,at their clinically relevant doses and frequency does not induce a significant hepatotoxicity in the mice. | Satyanarayana R Pondugula Julia M Salamat Kodye L Abbott Patrick C Flannery Mohammed Majrashi Mohammed Almaghrabi Manoj Govindarajulu Sindhu Ramesh Maninder Sandey Suneel K Onterue Chen-Che J Huang Yoshimi Iwaki Kristina Gill Natasha Narayanan Edwin McElroy Darshini Desai Rishi Nadar Timothy Moore Muralikrishnan Dhanasekaran | 2021 | Liver Research2021，5，4： | 1 |
| 17 | Differential regu- lation of hepatic cytochrome P450 monoxygenases in strep- tozotocin-induced diabetic rats显示文摘 | Sindhu R K Koo J R Sindhu K K | 2006 | Free Radical Research2006，40，： | 1 |
| 18 | Degradation studies of coir fiber/polyester and glass fiber/polyester composites under different conditions显示文摘 | SINDHU K JOSEPH K JOSEPH J M | 2007 | J Reinforced Plast Compos2007，26，15： | 1 |
| 19 | Effect of antimony substitution on structural and electrical properties of LaFeO3 显示文摘 | BERCHMANS L J SINDHU R ANGAPPAN S AUGUSTIN C O | 2008 | J Mater Process Technol2008，207，13： | 1 |
| 20 | A high-fat,refined-carbohydrate diet induces endothelial dysfunction and oxidant/antioxidant imbalance and depresses NOS protein expression显示文摘 | ROBERTS C K BARNARD J R SINDHU R K | 2005 | J Appl Physiol2005，98，： | 1 |
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