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| 1 | The human immun- odeficiency virus protease inhibitor ritonavir inhibits lung cancer cells,in part,by inhibition of surviving 显示文摘 | Srirangam A Milani M Mitra R | 2011 | Jour- nal of Thoracic Oncology2011，6，4： | 1 |
| 2 | Solubility, stability, physicochemical characteristics and in vitro ocular tissue permeability of hesperidin: a natural bioflavonoid 显示文摘 | MAJUMDAR S SRIRANGAM R | 2009 | Pharm Res2009，26，5： | 1 |
| 3 | Contemporary practice of percutancous nephrolithotomy : review of practice in a single region of the UK 显示文摘 | Srirangam S J Darling R Stopford M | 2008 | Ann R Coll Surg Engl2008，90，1： | 1 |
| 4 | Solubility, stability, physicochemical characteristics and in vitro ocular tissue permeability of hesperidin: a natural bilflavonoid显示文摘 | Majumdar S Srirangam R | 2009 | Pharm Res2009，26，5： | 1 |
| 5 | Contemporary practice of percutaneous nephrolithotomy: review of practice in a single region of the UK显示文摘 | Srirangam SJ Darling R Stopford M | 2008 | Ann R Coll Surg Engl2008，90，1： | 1 |
| 6 | Contemporary practice of percutaneous nephrolithotomy:review of practice in a single region of the UK显示文摘 | Srirangam S J Darling R Stopford M | 2008 | Ann R Coll Surg Engl2008，90，1： | 1 |
| 7 | The human immu- nodeficiency virus protease inhibitor ritonavir inhibits lung cancer cells, in part, by inhibition of survivin 显示文摘 | Srirangam A Milani M Mitra R | 2011 | J Tho- rac Oncol2011，6，4： | 1 |
| 8 | Contemporary practice of percutaneous nephrolithotomy:review of practice in a single region of UK显示文摘 | Srirangam SJ Darling R Stopford M | | 0，，1： | 1 |
| 9 | Contemporary practice of percutaneous nephrolithotomy:review of practice in a single region of the UK显示文摘 | Srirangam SJ Darling R Stopford M | 2008 | Ann Coll Surg Engl2008，90，1： | 1 |
| 10 | Diethylstilboestrol versus bicalutamide in hormone refractory prostate carcinoma:a prospective randomized trial显示文摘 | Manikandan R Srirangam SJ Pearson E | 2005 | Urol Int2005，75，： | 1 |
| 11 | Phytochemicals in ocular health: Therapeutic potential and delivery challenges显示文摘Diabetic retinopathy(DR) and age-related macular degeneration(AMD) are the leading causes of blindness in adults. The impact of these conditions on the quality of life is increasing in significance with a rise in life expectancy. The role of hyperglycemia, oxidative stress and inflammatory responses in the development and/or progression of DR and AMD, and several other sight threatening ocular diseases, is well established. In proliferative retinopathy, signals sent by the retina for nourishment, triggers the growth of fragile and abnormal blood vessels. Changes in ocular pressure may lead to rupture of these blood vessels causing severe vision problems. Recent in vitro and preclinical studies demonstrate that certain phytochemicals possessing potent antioxidant and anti-inflammatory activity and ocular blood flow enhancing properties may be very useful in the treatment of, or as a prophylactic measure for, DR and AMD. Apart from these properties they have also been investigated for their anti-bacterial, hormonal, enzyme stimulation, and anti-angiogenic activities. The attractive aspect of these potential therapeutic candidates is that they can act on multiplepathways identified in the etiology of DR, AMD, cataract and other ocular diseases. However, results from clinical trials have been somewhat ambiguous, raising questions about the concentrations of these bioflavonoids achieved in the neural retina following oral administration. Unfortunately, as of date, an efficient noninvasive means to deliver therapeutic agents/candidates to the back-of-the eye is still not available. This review examines some of these promising natural agents and discusses the challenges encountered in delivering them to the posterior segment ocular tissues through the oral route. | Goutham R Adelli Ramesh Srirangam Soumyajit Majumdar | 2013 | World Journal of Pharmacology2013，2，1： | 0 |
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