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| 1 | Nationwide trends and predictors of inpatient mortality in 83884 transjugular intrahepatic portosystemic shunt显示文摘AIM: To evaluate and validate the national trends and predictors of in-patient mortality of transjugular intrahepatic portosystemic shunt(TIPS) in 15 years.METHODS: Using the National Inpatient Sample which is a part of Health Cost and Utilization Project, we identified a discharge-weighted national estimate of 83884 TIPS procedures performed in the United States from 1998 to 2012 using international classification of diseases-9 procedural code 39.1. The demographic, hospital and co-morbility data were analyzed using a multivariant analysis. Using multi-nominal logistic regression analysis, we determined predictive factors related to increases in-hospital mortality. Comorbidity measures are in accordance to the Comorbidity Software designed by the Agency for Healthcare Research and Quality.RESULTS: Overall, 12.3% of patients died during hospitalization with downward trend in-hospitalmortality with the mean length of stay of 10.8 ± 13.1 d. Notable, African American patients(OR = 1.809 vs Caucasian patients, P < 0.001), transferred patients(OR = 1.347 vs non-transferred, P < 0.001), emergency admissions(OR = 3.032 vs elective cases, P < 0.001), patients in the Northeast region(OR = 1.449 vs West, P < 0.001) had significantly higher odds of inhospital mortality. Number of diagnoses and number of procedures showed positive correlations with in-hospital death(OR = 1.249 per one increase in number of procedures). Patients diagnosed with acute respiratory failure(OR = 8.246), acute kidney failure(OR = 4.359), hepatic encephalopathy(OR = 2.217) and esophageal variceal bleeding(OR = 2.187) were at considerably higher odds of in-hospital death compared with ascites(OR = 0.136, P < 0.001). Comorbidity measures with the highest odds of in-hospital death were fluid and electrolyte disorders(OR = 2.823), coagulopathy(OR = 2.016), and lymphoma(OR = 1.842).CONCLUSION: The overall mortality of the TIPS procedure is steadily decreasing, though the length of stay has remained relatively constant. Specific patient ethnicity, location, transfer status, primary diagnosis and comorbidities correlate with increased odds of TIPS in-hospital death. | Edward Wolfgang Lee Andrew Kuei Sammy Saab Ronald W Busuttil Francisco Durazo Steven-Huy Han Mohamed M El-Kabany Justin P Mc Williams Stephen T Kee | 2016 | World Journal of Gastroenterology2016，22，25： | 7 |
| 2 | Impact of enclosure management on soil properties and microbial biomass in a restored semi-arid rangeland, Kenya显示文摘Rangeland degradation is a serious problem throughout sub-Saharan Africa and its restoration is a challenge for the management of arid and semi-arid areas. In Lake Baringo Basin of Kenya, communities and individual farmers are restoring indigenous vegetation inside enclosures in an effort to combat severe land degradation and address their livelihood problems. This study evaluated the impact of enclosure management on soil properties and microbial biomass, being key indicators of soil ecosystem health. Six reseeded communal enclosures using soil embankments as water-harvesting structures and strictly regulated access were selected, varying in age from 13 to 23 years. In six private enclosures, ranging from 3 to 17 years in age, individual farmers emulated the communal enclosure strategy and restored areas for their exclusive use. Significant decreases in bulk density, and increases in the soil organic carbon, total nitrogen and microbial biomass contents and stocks were found in the enclosures as compared with the degraded open rangeland. In the private enclosures, the impact of rehabilitation on the soil quality was variable, and soil quality was in general lower than that obtained under communal management. The significant increase of absolute stocks of carbon, nitrogen and microbial biomass compared to the degraded open rangeland indicates the potential for the restoration of soil quality through range rehabilitation. Over-sowing with indigenous legume fodder species could improve total nitrogen content in the soil and nutritional value of the pastures as well. | Stephen M MUREITHI Ann VERDOODT Charles KK GACHENE Jesse T NJOKA Vivian O WASONGA Stefaan De NEVE Elizabeth MEYERHOFF Eric Van RANST | 2014 | Journal of Arid Land2014，6，5： | 3 |
| 3 | Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial显示文摘 | Matthew T Seymour Lindsay C Thompson Harpreet S Wasan Gary Middleton Alison E Brewster Stephen F Shepherd M Sinead O’Mahony Timothy S Maughan Mahesh Parmar Ruth E Langley | 2011 | The Lancet2011，，9779： | 2 |
| 4 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 5 | Release of Vasoactive substances during Cardiopulmonary Bypass 显示文摘 | Stephen W Haak T Bacattik M | 1992 | Ann Thorac Surg1992，54，： | 1 |
| 6 | Seismic behavior and design of unbonded post-tensioned preeast concrete frames显示文摘 | EL-SHEIKH M T RICHARD S STEPHEN P | 1999 | PCI Journal1999，44，3： | 1 |
| 7 | The role of neuropeptide Y in the antiobesity action of the obese gene product显示文摘 | Stephens T Basinski M Bristow P | 1995 | Nature1995，377，2： | 1 |
| 8 | In situ investigation of the calcium-induced proteolytic and salting-in mechanisms causing tenderization in calcium-enhanced muscle显示文摘 | Lawrance T E Dikeman M E Stephens J W | 2003 | Meat Sci2003，66，： | 1 |
| 9 | Sequence Logos: A New Way to Display Consensus Sequences 显示文摘 | SCHNEIDER T D STEPHENS R M | 1990 | Nuclcic Acids Res1990，18，20： | 1 |
| 10 | Carbohydrate polymers from aloe ferox leaves显示文摘 | Mabusela Wilfred T Stephen Alistair M Botha Marthinus C | 1990 | Phytochemistry1990，29，11： | 1 |
| 11 | Acid Initiation of Ammonia-Borane Dehydrogenation for Hydrogen Storage显示文摘 | STEPHENS F H BAKER R T MATUS M H | 2007 | Angew Chem Int Ed2007，46，5： | 1 |
| 12 | Characterization of petro physical flow units in carbonate reservoirs显示文摘 | Alden J M Stephen T S Dan J H | 1997 | AAPG Bulletin1997，81，5： | 1 |
| 13 | Gradient projection for sparse reconstruction: application to compressed sensing and other inverse problems 显示文摘 | Figueiredo M T Nowak R D Stephen J W | 2007 | IEEE Journal of Selected Topics in Signal Processing2007，1，4： | 1 |
| 14 | Investigation of benzene oxide in bone marrow and other tissues of F344 rats following metabolism of benzene in vitro and in vivo 显示文摘 | Andrew B L Karen YO C Suramya W Thomas A M Bernard T G Stephen M R | 1998 | Chemical Research in Toxicology1998，11，4： | 1 |
| 15 | Magnetization behaviour of electrodeposited Ni Mn alloys显示文摘 | Stephen A Nagarajan T Ananth M V | 1998 | Materials Science and Engineering1998，55，： | 1 |
| 16 | A numerical study of flow and heat transfer in a smooth and ribbed U-duct with and without rotation显示文摘 | LIN Y L SHIH T I P STEPHENS M A | 2001 | Journal of Heat Transfer2001，123，： | 1 |
| 17 | Quantum theory of rotation angles显示文摘 | STEPHEN M B PEGGD T | 1990 | Phys Rev1990，41，： | 1 |
| 18 | The role of neuropeptide Y in the antiobesity action of the obese gene product显示文摘 | Stephens T W Basinski M Bristow P K | 1995 | Nature1995，377，6549： | 1 |
| 19 | Nanoscale Atoms in Solid- State Chemistry 显示文摘 | Roy X Lee C H Crowther A C Schenck C L Besara T Lalancette R A Siegrist T Stephens P W Brus L E Kim P Steigerwald M L Nuckolls C | 2013 | Science2013，，341： | 1 |
| 20 | A compact 3D imaging laser radar system using Geiger-mode APD arrays: system and measurements显示文摘 | MARINO R M STEPHENS T HATCH R E | 2003 | SPIE2003，5086，： | 1 |
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