维普中文期刊产品整合服务
9篇 您的检索式:作者名="SUNEEL D"
    题名 作者 年代 出处 被引量
1Enzymatic polishing of rice-a new processing technology显示文摘Mithu D Suneel G Vishal K 2008Food Science and Technology2008,41,10:1
2Mucoadhesive buccal tablets of domperidone:formulationevaluation and effects of process variables 显示文摘Suneel L P Nilesh T H Ujjalkumar D 2014J Pharm Investig2014,44,2:1
3Defining the dynamics of self-assembled Fas-receptor activation显示文摘Suneel D Mundle Azra Raza 2002Trends in Immunology2002,23,4:1
4Signal antonymy unique to myelodysplastic marrows correlates with altered expression of E2F1显示文摘 YIFWAYIMARE M JONATHAN D C 2000Br J Haematol2000,109,2:1
5Enzymatic polishing of rice: a new processing technology显示文摘M1THU D SUNEEL G VISHAL K 2008LWT - Food Science and Technology2008,41,10:1
6Enzymatic polishing of rice: a new processing technology显示文摘MITHU D SUNEEL G VISHAL K 2008LWT - Food Science and Technology2008,41,10:1
7Defining the dynamics of self-assembled Fas-receptor activation 显示文摘SUNEEL D MUNDLE AZRA RAZA 2002Trends in Immunology2002,23,4:1
8Defining the dynamics of self-assembled Fas-receptor activation显示文摘Suneel D Mundle Azra Raza 2002Trends in Immunology2002,23,4:1
9Apalutamide for metastatic castration-sensitive prostate cancer:final analysis of the Asian subpopulation in the TITAN trial显示文摘The final analysis of the phase 3 Targeted Investigational Treatment Analysis of Novel Anti-androgen(TITAN)trial showed improvement in overall survival(OS)and other efficacy endpoints with apalutamide plus androgen deprivation therapy(ADT)versus ADT alone in patients with metastatic castration-sensitive prostate cancer(mCSPC).As ethnicity and regional differences may affect treatment outcomes in advanced prostate cancer,a post hoc final analysis was conducted to assess the efficacy and safety of apalutamide in the Asian subpopulation.Event-driven endpoints were OS,and time from randomization to initiation of castration resistance,prostate-specific antigen(PSA)progression,and second progression-free survival(PFS2)on first subsequent therapy or death.Efficacy endpoints were assessed using the Kaplan–Meier method and Cox proportional-hazards models without formal statistical testing and adjustment for multiplicity.Participating Asian patients received once-daily apalutamide 240 mg(n=111)or placebo(n=110)plus ADT.After a median follow-up of 42.5 months and despite crossover of 47 placebo recipients to open-label apalutamide,apalutamide reduced the risk of death by 32%(hazard ratio[HR]:0.68;95%confidence interval[CI]:0.42–1.13),risk of castration resistance by 69%(HR:0.31;95%CI:0.21–0.46),PSA progression by 79%(HR:0.21;95%CI:0.13–0.35)and PFS2 by 24%(HR:0.76;95%CI:0.44–1.29)relative to placebo.The outcomes were comparable between subgroups with low-and high-volume disease at baseline.No new safety issues were identified.Apalutamide provides valuable clinical benefits to Asian patients with mCSPC,with an efficacy and safety profile consistent with that in the overall patient population.Byung Ha Chung Jian Huang Hiroji Uemura Young Deuk Choi Zhang-Qun Ye Hiroyoshi Suzuki Taek Won Kang Da-Lin He Jae Young Joung Sabine D Brookman-May Sharon McCarthy Amitabha Bhaumik Anildeep Singh Suneel Mundle Simon Chowdhury Neeraj Agarwal Ding-Wei Ye Kim N Chi Hirotsugu Uemura 2023Asian Journal of Andrology2023,25,6:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费