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1Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets.Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo 2021World Journal of Clinical Oncology2021,12,10:5
2卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景 缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 2017国际脑血管病杂志2017,25,5:2
3A comparative evaluation of microalgae for the degradation of piggery wastewater under photosynthetic oxygenation显示文摘Ignacio de Godos Virginia A. Vargas Saúl Blanco María C. García González Roberto Soto Pedro A. García-Encina Eloy Becares Raúl Mu?oz 2010Bioresource Technology2010,,14:2
4The murine gastrin promoter is synergistically activated by transforming growth factor-beta/SMAD and Wnt signaling pathways显示文摘Lei SA Dubeykovskiy A Chakladar L 2004J Biol Chem2004,279,42:1
5CYP2E1 polymorphism,cigarette smoking,p53 expression,and survival in non-small cell lung cancer: a long term follow-up study显示文摘Haque AK Au W Ca j a s -Sa l a z a r N e t al 2004Appl Immunohistochem Mol Morphol2004,12,4:1
6Fruiting body, spores and in vitro produced mycelium of Ganoderma lu- cidum from Northeast Portugal: A comparative study of the antioxidant potential of phenolic and polysaccharidic ex- tracts显示文摘Heleno SA Barros L Martins A 2012Food Research International2012,46,1:1
7Periprosthetic frac tures in the resurfaced hip-A case report and review of the lit- erature显示文摘Brennan SA Devitt BM O'Neill CJ et a l 2013Injury2013,44,2:1
8The three main stumbling blocks for anticancer T cells 显示文摘Baitsch L Fuertes-Marraco SA Legat A 2012Trends Immunol2012,33,7:1
9Implantable cardioverter defibrillators and Chagas disease : results of the ICD registry Latin America显示文摘MURATORE C A BATISTA SA L A CHIALE P A 2009Europace2009,11,:1
10A comparative study of sensor array and GC-MS:application to Madrid wines characterization显示文摘Santos JP Arroyo T Aleixandre M Lozano J Sayago I García M Femández MJ Arésa L Gutiérrez J Cabellos JM Gil M Horrillo MC 0,,02:1
11Effect of tea drinking on blood lipids,blood pressure and aspects of bowel habit显示文摘Bingham SA Vorster H Jerling JC Magee L Mulligan A Runswick S Cummings JH 0,,:1
12Youth risk behav- ior surveillance-United States, 2001显示文摘Grunbaum J A Kann L Killellen SA 2002Sch Health2002,72,8:1
13Treatment of infertility in women with polycystic ovary syndrome 显示文摘Santana L F Ferriani R A Sa M F 2008Rev Bras Ginecol Obstet2008,30,4:1
14Atmospheric surface layer characteristics of turbulence above the Pantanal wetland regarding the similarity theory显示文摘Marques Filho E P Sa L D A Karam H A 2008Agricultural and Forest Meteorology2008,148,67:1
15Phytoestrogens: where are we now显示文摘Bingham SA Atkinson C Liggins J Bluck L Coward A 1998Br J Nutr1998,79,:1
16Time-of-use tariff design under uncertainty in price-elasticities of electricity demand: A stochastic optimization approach 显示文摘DE Sa FERREIRA R BARROSO L A LINO P R 2013IEEE Transactions on Smart Grid2013,4,4:1
17Kinetic curves of malignant lesions are not consistent across MRI systems: need for improved stand ardization of breast dynamic contrast enhanced MRI cquisition 显示文摘Jansen SA Shimauchi A Zak L 2009AJR2009,193,3:1
18Screening for devel- opmental dysplasia of hip: a systematic Literature review for the US Preventive Services Task Force 显示文摘Shipman SA H elf and M Moyer VA et a l 2006Pediatrics2006,117,3:1
19Elevated tissue plasminogen aetivator as a potential marker of end othelialdysfunetion in pre- eclampsia: correlation with proteinnuria 显示文摘Belo L Santos SA Rumley A 2002BJOG2002,109,11:1
20Kawasaki di- sease: a review of pathologic features of stage IV disease and two cases of sudden death among asymptotic young adults 显示文摘Rozin L Koehler SA Shakir A 2003Am J Forensic Med Pathol2003,24,1:1
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