2篇
您的检索式：作者名="Saeromi Kim"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Quantitative autonomic function test in differentiation of multiple system atrophy from idiopathic Parkinson disease显示文摘Background:Differential diagnosis of idiopathic Parkinson disease (IPD) and multiple system atrophy-Parkinson type (MSA-P) is challenging since they share clinical features with parkinsonism and autonomic dysfunction.To distinguish MSA-P from IPD when the symptoms are relatively mild,we investigated the usefulness of the quantitative fractionalized autonomic indexes and evaluated the correlations of autonomic test indexes and functional status.Methods:Thirty-six patients with parkinsonism (22 with IPD and 14 with MSA-P) in Soonchunhyang University Bucheon Hospital from February 2014 to June 2015 were prospectively enrolled in the study.We compared fractionalized autonomic indexes and composite autonomic scoring scale between patients with IPD and MSA-P with Hoehn and Yahr (H&Y) score ≤3.Parasympathetic indexes included expiratory/inspiratory ratio during deep breathing,Valsalva ratio (VR),and regression slope of systolic blood pressure (BP) in early phase Ⅱ (vagal baroreflex sensitivity) during Valsalva maneuver.Sympathetic adrenergic indexes were pressure recovery time (PRT) and adrenergic baroreflex sensitivity (BRSa) (BP decrement associated with phase 3 divided by the PRT),sympathetic index 1,sympathetic index 3,early phase Ⅱ mean BP drop,and pulse pressure reduction rate.Additionally,we compared the unified multiple system atrophy rating scale (UMSARS) and H&Y scores and the autonomic indexes in all patients.Results:PRT was significantly different between the IPD and MSA-P groups (P =0.004) despite the similar BP drop during tilt.Cutoff value of PRT was 5.5 s (sensitivity,71.4%;specificity,72.7%).VR (r =-0.455,P =0.009) and BRSa (r =-0.356,P =0.036) demonstrated a significant correlation with UMSARS and H&Y scores.Conclusions:Among the cardiovascular autonomic indexes,PRT can be a useful parameter in differentiating the early stage of MSA-P from that of IPD.Moreover,VR,and BRSa may be the optimal indexes in determining functional symptom severity. | Ji-Yun Park Dongseok Yang Hei-Jun Yang Hyun Ah Kim Saeromi Kim Deokhyun Heo Jeong-Ho Park Eek-Sung Lee Tae-Kyeong Lee | 2019 | Chinese Medical Journal2019，，16： | 1 |
| 2 | Omega-3 fatty acids induce Ca2+ mobilization responses in human colon epithelial cell lines endogenously expressing FFA4显示文摘瞄准: 免费的丰满的酸受体 4 (FFA4;先前作为 GPR120 知道) 为 omega-3 多元不堡和是 G 联合蛋白质的受体(GPCR ) 丰满的酸。FFA4 在老鼠和人的小肠和冒号被发现了到快车。在这研究,我们调查 omega-3 多元不堡和的效果在人的冒号的 FFA4 上的丰满的酸在 vitro 的上皮的房间。 | Jung-min KIM Kyoung-pil LEE Soo-jin PARK Saeromi KANG Jin HUANG Jung-min LEE Koichi SATO Hae-young CHUNG Fumikazu OKAJIMA Dong-soon IM | 2015 | Acta Pharmacologica Sinica2015，36，7： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员