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| 1 | Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults显示文摘AIM: To evaluate the effects of three potentially anti- inflammatory probiotic bacteria from three different genera on immune variables in healthy adults in a clinical setting based on previous in vitro characterization of cytokine responses. METHODS: A total of 62 volunteers participated in this randomized, double-blind and placebo-controlled parallel group intervention study. The volunteers were randomized to receive a milk-based drink containing either Lactobacillus rhamnosus GG (LGG), Bifidobacterium animalis ssp. lactis Bb12 (Bb12), or Propionibacterium freudenreichii ssp. shermanii JS (PJS) or a placebo drink for 3 wk. Venous blood and saliva samples were taken at baseline and on d 1, 7 and 21. Fecal samples were collected at baseline and at the end of intervention. RESULTS: The serum hsCRP expressed as the median AUC0-21 (minus baseline) was 0.018 mg/L in the placebo group, -0.240 mg/L in the LGG group, 0.090 mg/L in the Bb12 group and -0.085 mg/L in the PJS group (P = 0.014). In vitro production of TNF-α from in vitro cultured peripheral blood mononuclear cells (PBMC) was significantly lower in subjects receiving LGG vs placebo. IL-2 production from PBMC in the Bb12 group was significantly lower compared with the other groups. CONCLUSION: In conclusion, probiotic bacteria have strain-specific anti-inflammatory effects in healthy adults. | Riina A Kekkonen Netta Lummela Heli Karjalainen Sinikka Latvala Soile Tynkkynen Salme Jrvenp Hannu Kautiainen Ilkka Julkunen Heikki Vapaatalo Riitta Korpela | 2008 | World Journal of Gastroenterology2008，14，13： | 6 |
| 2 | Protein-losing pseudomembranous colitis with cap polyposis-like features显示文摘Protein-losing enteropathy(PLE) is characterized by loss of serum proteins into the gastrointestinal tract. It may lead to hypoproteinemia and clinically present as protein deficiency edema, ascites, pleural or pericardial effusion and/or malnutrition. In most cases the site of protein loss is the small intestine. Here we present an unusual case of severe PLE in a 55-year old female with a one-year history of recurrent diarrhea, crampy abdominal pain, and peripheral edema. Endoscopy and MRI showed a diffuse inflammatory thickening of the sigmoid colon and the rectum. Surgical resection of the involved colon was performed and the symptoms were significantly resolved. The final histologic evaluation confirmed a diagnosis of a pseudomembranous colitis with cap polyposis-like features. Such a cause of PLE has never been described before. | Wolfgang Kreisel Guenther Ruf Richard Salm Adhara Lazaro Bertram Bengsch Anna-Maria Globig Paul Fisch Silke Lassmann Annette Schmitt-Graeff | 2017 | World Journal of Gastroenterology2017，23，16： | 2 |
| 3 | Noninvasive coronary imaging and assessmcnt of left ventricular function using 16 -slice, compu ted tomography显示文摘 | Sehuijf JD BaxJj Salm LP | 2005 | Am J Cardiol2005，95，： | 1 |
| 4 | Neoplasm of the bladder and cystitis cystica 显示文摘 | Salm R | 1967 | Brit J Urol1967，39，： | 1 |
| 5 | What constitutes optimal surgical revascularization? Answers from the Bypass Angioplasty Revascularization Investigation (BARI) 显示文摘 | Vander Salm TJ Kip KE Jones RH | 2002 | J Am Coil Cardiol2002，39，： | 1 |
| 6 | Experience with TEM in Germany显示文摘 | Salm R Lampe H Bustos A | 1994 | Endosc Surg Allied Technol1994，2，5： | 1 |
| 7 | Characterization of Modified Fischer–Tropsch Catalysts Promoted with Alkaline Metals for Higher Alcohol Synthesis显示文摘 | Ana Cosultchi Miguel Pérez-Luna José Antonio Morales-Serna Manuel Salmón | 2012 | Catalysis Letters2012，，3： | 1 |
| 8 | Treating very ear- ly rheumatoid arthritis显示文摘 | Raza K Bu ckley C E Salm onM | 2006 | Best Pract Res Clin Rheumato2006，20，5： | 1 |
| 9 | Liquid chromatography-tandem mass spectrometry method for the simultaneous quantitative determination of the organophosphorus pesticides dimethoate, fenthiou, diazinon and chlorpyrifos in human blood 显示文摘 | SALM P TAYLOR P J ROBERTS D | 2009 | J Chromatogr B2009，877，： | 1 |
| 10 | The acute stress response of red porgy, Pagrus pagrus, kept on a red or white background 显示文摘 | van der SALM A L PAVLIDIS M FLIK G | 2006 | General and Comparative Endocrinology2006，145，3： | 1 |
| 11 | High-performance liquid chromatography-tandem mass spectrometry as a reference for analysis of taerolimus to assess two immtmoassays in patients with liver and renal transplants显示文摘 | Salm P Taylor PJ Clark A | 1997 | Ther Drug Monit1997，19，6： | 1 |
| 12 | Increased morphological diversity of microglia in the activated hypothalamic supraoptic nucleus显示文摘 | Ayoub AE Salm AK | 2003 | J Neurosci2003，23，21： | 1 |
| 13 | Mild prenatal stress in rats is associated with enhanced conditioned fear显示文摘 | GRIFFIN WC 3RD SKINNER HD SALM AK | 2003 | Physiol Behav2003，79，2： | 1 |
| 14 | The phosphoinositide 3-kinakse signalingpathway as a therapeutic target in grade IV brain tumors 显示文摘 | ]Inland K Salm FT Arcaro A | 2011 | CurrCancer Drug Targets2011，11，8： | 1 |
| 15 | The PET-boost randomised phase II dose-escalation trial in non-small cell lung cancer 显示文摘 | van Elmpt W De Ruysscher D van der Salm A | 2012 | Radiother Oncol2012，104，1： | 1 |
| 16 | Texture profile analysis of meat products treated with commercial liquid smoke flavourings显示文摘 | O Martinez J Salme Rorn MD Guillen | 2004 | Food Control2004，15，： | 1 |
| 17 | Do individual index futures investors destabilize the underlying spot market 显示文摘 | Bohl M T Salm C A Wilfling M | 2011 | Journal of Futures Markets2011，31，1： | 1 |
| 18 | Insulin resistance,and colorectal adenoma risk显示文摘 | Gronroos M Salm TA Vuento MH | | 0，，04： | 1 |
| 19 | Price discovery and investor structure in stock index futures显示文摘 | Bohl M T Salm C A Schuppli M | 2011 | Journal of Futures Markets2011，31，3： | 1 |
| 20 | Effects of husbandry conditions on the skin colour and stress response of red porgy, Pagrus pagrus显示文摘 | Salm A L Martinez M Flik G | 2004 | Aquaculture2004，241，： | 1 |
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