| 1 | Optimization and modeling of glyphosate biodegradation by a novel Comamonas odontotermitis P2 through response surface methodology显示文摘Glyphosate is an important organophosphonate herbicide used to eliminate grasses and herbaceous plants in many vegetation management situations.Its extensive use is causing environmental pollution,and consequently,there is a need to remove it from the environment using an eco-friendly and cost-effective method.As a step to address this problem,a novel bacterial strain Comamonas odontotermitis F2,capable to utilize glyphosate as a carbon(C)and/or phosphorus(P)source,was isolated from a glyphostate-contaminated field soil in Australia and characterized.Response surface methodology(RSM)employing a 2^3 full factorial central composite design was used to optimize glyphosate degradation by C.odontotermitis P2 under various culture conditions.The strain C.odontotermitis P2 was proficient in degrading 1.5 g L^-1 glyphosate completely within 104 h.The optimal conditions for the degradation of glyphosate were found to be pH 7.4,29.9℃,and an inoculum density of 0.54 g L^-1,resulting in a maximum degradation of 90%.Sequencing of glyphosate oxidoreductase(GOX)and C-P lyase(phnJ)genes from C.odontotermitis P2 revealed 999c and 93%identities to already reported bacterial GOX and phnJ genes,respectively.The presence of these two genes in C.odontotermitis indicates its potential to degrade glyphosate through GOX and C-P lyase metabolic pathways.This study demonstrates the potential of C.odontotermitis P2 for efficient degradation of glyphosate,which can be exploited for remediation of glyphosate. | Sadiqa FIRDOUS Samina IQBAL Samina ANWAR | 2020 | Pedosphere2020，30，5： | 2 |
| 4 | Metal-Doped Brushite Cement for Bone Regeneration显示文摘For the past several years,calcium phosphate cement was used in the biomedical applications.Outstanding biocompatibility,good bioactivity,self-setting qualities,minimum setting degree,appropriate toughness,and simple shape to accommodate any difficult geometry are among their most notable attributes.Calcium phosphate has some types and brushite is one of the most attractive mineral for bone repair application.Brushite is extensively employed in filling fractures and trauma treatments as a bone substituted material.This kind of material can potentially be used as a medicine delivery device.The replacement of metal,such as magnesium,zinc,and strontium ions,into the calcium phosphate structure is a major research topic these days.Brushite cement has low mechanical strength and quick setting rate.It is possible to produce biomaterials with higher mechanical characteristics.By adding metal that are great potential in controlling cellular density when included into biomaterials.As a result,it is a successful method to develop quite well regenerative medicine.This paper provides a detailed summary of the present achievements of metal-doped brushite cement for bone repair and healing process.The major purpose of this work is to give a simple but thorough analysis of current successes in brushite cement doped with Zn,Mg,Sr,and other ions as well as to highlight new advancements and prospects.The impact of metal replacement on cement physical and chemical properties,including microstructure,setting time,injectability,mechanical property,and ion release,is explored.The metal-doped cement has osteogenesis,angiogenesis,and antibacterial properties,as well as their prospective utility as drug carriers,also considered. | Muhammad Aqib Aneela Anwar Humayun Ajaz Samina Akbar Ahsan Manzoor Maham Abid Zohaib Waheed Qudsia Kanwal | 2023 | Journal of Bionic Engineering2023，20，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员