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| 1 | From traditional serrated adenoma to tubulovillous adenoma and beyond显示文摘It is well established that colorectal cancer develops from a series of precursor epithelial polyps, including tubular adenomas, villous/tubulovillous adenomas(VA/TVA), sessile serrated adenomas(SSA) and traditional serrated adenomas(TSA). Of these, TSAs are least common and account for only 5% of all serrated polyps. TSAs are characterised by the presence of a 'pinecone-like' architecture, granular eosinophilic cytoplasm, luminal serrations, ectopic crypt foci(ECF) and elongated, pencillate nuclei. However, the distinct slit-like luminal serrations, reminiscent of small bowel mucosa, appear to be the most unique and reproducible feature to distinguish TSAs from other polyps. There is a contention that TSAs are not inherently dysplastic and that the majority do not show cytological atypia. Two types of dysplasia are associated with TSA. Serrated dysplasia is less well recognised and less commonly encountered than adenomatous dysplasia. In addition, it is now becoming increasingly evident that TSAs can be admixed with HP, SSA and VA/TVA. At a genetic level, polyps may switch phenotype as they accumulate genetic changes, evolving from a serrated pathway to a more conventional one, which could be the basis for a spectrum theory starting out with a TSA with serration and ECF evolving into a TSA with conventional dysplasia and, eventually, to a well-developed conventional adenoma. Nevertheless, there is an exigency for future studies to provide further illumination and bridge the gaps in our present understanding. | Sangeetha N Kalimuthu Adeline Chelliah Runjan Chetty | 2016 | World Journal of Gastrointestinal Oncology2016，8，12： | 2 |
| 2 | A survey on recent security trends using quantum cryptography 显示文摘 | RUBYA T PREMA L N SANGEETHA B | 2010 | Intemation Jounal on Computer Science and Engineering2010，2，9： | 1 |
| 3 | Recent trends in the microbial production, analysis and application of fructooligosaccharides显示文摘 | SANGEETHA P T RAMESH M N PRAPULLA S G | 2005 | Trends in Food Science and Technology2005，16，： | 1 |
| 4 | Tannins present in Cichorium intybus enhance glucose uptake and inhibit adipogenesis in 3T3-L1 adipocytes through PTP1B inhibition 显示文摘 | Muthusamy V S Anand S Sangeetha K N | 2008 | Chem-Biol Interact2008，174，1： | 1 |
| 5 | Supramolecular gels functions and uses显示文摘 | SANGEETHA N M MAITRA U | 2005 | Chem Soc Rev2005，34，： | 1 |
| 6 | Recent trends in the microbial production,analysis and application of fructooligosaccharides显示文摘 | SANGEETHA P T RAMESH M N PRAPULLA S G | 2005 | Trends in Food Science&Technology2005，16，10： | 1 |
| 7 | Minimum fluidization velocity at high temperature based on Geldart powder classification显示文摘 | Sangeetha V Swathy R Narayanamurthy N et al | 2000 | Chemical Engineering Technology2000，23，8： | 1 |
| 8 | Silibinin modu- lates biotransforming microbial enzymes and pre- vents 1, 2-dimethylhydrazine-induced preneoplastic changes in experimental colon cancer显示文摘 | Sangeetha N Felix AJ Nalini N | 2009 | Eur J Cancer Prey2009，18，5： | 1 |
| 9 | Bimetallic Au- Ag/CeO2 catalysts for preferential oxidation of CO in hydrogen-rich stream:Effect of calcination temperature 显示文摘 | Sasirekha N Sangeetha P Chen Y W | 2014 | J Phys Chem C2014，8，15： | 1 |
| 10 | Recent trends in the microbial production,analysis and application of Fructooligosaccharides显示文摘 | Sangeetha P T Ramesh M N Prapulla S G | 2005 | Trends in Food Science & Technology2005，16，10： | 1 |
| 11 | Silibinin modulates biotransforming microbial enzymes and prevents 1,2-dimethyllij, drazitie- induced preneoplastic changes in experimental colon cancer显示文摘 | Sangeetha N Felix A J Nalini N | 2009 | Eur J Cancer Prey2009，18，5： | 1 |
| 12 | Natural rubber producing plants: An overview显示文摘 | Venkatachalam P Geetha N Sangeetha P | 2013 | African Journal of Biotechnology2013，12，12： | 1 |
| 13 | Fructooligosaccharide production using fructosyltransferase obtained from recycling culture of Aspergillus oryzae CFR 202 显示文摘 | Sangeetha P T Ramesh M N Prapulla S G | 2005 | Process Biochemistry2005，40，： | 1 |
| 14 | Supramolecular gels: Functions and uses 显示文摘 | Sangeetha N M Maitra U | 2005 | Chemical Society Reviews2005，34，10： | 1 |
| 15 | Antiphospholipid antibodies promote leuko cyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via heta2GPI and apoER2显示文摘 | Sangeetha Ramesh CrMg N Morre Cristina Taran- go | 2011 | J Clin Invest2011，121，1： | 1 |
| 16 | Mieellization of metallosurfactant n - dodecyl/hexadecyl/octadeeyl salicylaldimine cobalt (III ) complexes in nonaqneous media 显示文摘 | CALEB NOBLE CHANDAR S SANGEETHA D ARUMUGHAM M N | 2011 | J Solution Chem2011，40，： | 1 |
| 17 | Modulatory efficacy of hesperitin (citrus flavanone) on xenobiotie - metabolizing enzymes during 1 ', 2 - dimethylhydrazine - induced colon carcinogenesis 显示文摘 | Aranganathan S Selvam J P Sangeetha N | 2009 | Chemico - Biological Interactions2009，180，2： | 1 |
| 18 | cytotoxic action of cis-unsaturated fatty acdis on human cervical(HeLa)carcinoma cells in vitro显示文摘 | Sangeetha P S Das U N | 1995 | Pr Prostagland Leukot ES-sent Fatty Acids1995，，53： | 1 |
| 19 | Production of fruc- to-oligosaccharides by fructosyl transferase from Aspergillus o- ryzae CFR 202 and A ureobasidium pullulans CFR 77显示文摘 | Sangeetha P T Ramesh M N Prapulla S G | 2004 | Proc- ess Biochemistry2004，39，6： | 1 |
| 20 | Supramolecular gels: functions and uses 显示文摘 | SANGEETHA N M MAITRA U | 2005 | Chem Soc Rev2005，34，10： | 1 |
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