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| 1 | Synthesis, docking and ADMET prediction of novel 5-((5-substituted-1-H-1,2,4-triazol-3-yl) methyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine as antifungal agents显示文摘A novel series of 5-((5-substituted-1H-1,2,4-triazol-3-yl)methyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridines 5(a–i) has been synthesized from thienopyridine hydrazide, substituted aromatic nitriles using 4-dimethylaminopyridine(DMAP) as a catalyst under microwave irradiation and evaluated for their in vitro antifungal activity. Compound 5g is found to be more potent against Candida albicans when compared with miconazole. Docking study of the newly synthesized compounds was performed, and results showed good binding mode in the active site of fungal enzyme P450 cytochrome lanosterol 14 ademethylase. ADMET properties of synthesized compounds were also analyzed and showed good drug like properties. The results of in vitro antifungal activity, docking study and ADMET prediction revealed that the synthesized compounds have potential antifungal activity and can be further optimized and developed as a lead compound. | Jaiprakash N. Sangshetti Firoz A. Kalam Khan Rashmi S. Chouthe Manoj G. Damale Devanand B. Shinde | 2014 | Chinese Chemical Letters2014，25，7： | 6 |
| 2 | QbD in development and validation of a rapid RP-HPLC method for determination of Trospium chloride in bulk drug 显示文摘 | Zahid Zaheer Jaiprakash N Sangshetti Rana Z Ahmed | 2015 | Journal of Medicinal Chemistry and Drug Discovery2015，，： | 1 |
| 3 | Microwave assisted one-pot synthesis of some novel 2, 5-disubstituted 1,3,4-oxadiazoles as antifungal agents 显示文摘 | Sangshetti J N Chabukswar A R Shinde D B | 2011 | Bioorganic and Medicinal Chemistry Letters2011，21，1： | 1 |
| 4 | Stability Indicating LC Method For the Simultaneous Determination of Amlodipine and Olmesartan in Dosage Form显示文摘 | K.R. Patil V.P. Rane J.N. Sangshetti R.D. Yeole D.B. Shinde | 2010 | Journal of Chromatographic Science2010，，7： | 1 |
| 5 | Micro- wave assisted one pot synthesis of some novel 2,5-dis- ubstituted 1,3,4-oxadiazoles as antifungal agents显示文摘 | Sangshetti J N Chabukswar A R Shinde D B | 2011 | Bioorg Med Chem Lett2011，21，： | 1 |
| 6 | Synthesis of some novel 3- (1-( 1-substitutedpiperidin-4-yl)-1H-1, 2, 3-triazol-4- yl)-5-substituted phenyl-1,2,4-oxadiazoles as antifun- gal agents显示文摘 | Sangshetti J N Shinde D B | 2011 | Eur J Med Chem2011，46，： | 1 |
| 7 | 查看详情显示文摘 | Sangshetti J. N Kokare N. D Kotharkara S. A Shinde D.B | | 0，，： | 1 |
| 8 | Sodium bisulfite as an efficient and inexpensive catalyst for the one-pot synthesis of 2,4,5-tfiaryl-1H-imidazoles from benzil or benzoin and aromatic aldehydes 显示文摘 | JAIPRAKASH N SANGSHETTI NAGNNATH D KOKARE SANDEEP A | 2008 | Kotharkar Monatshefte fur Chemie2008，139，2： | 1 |
| 9 | Sulphanilic acid catalyzed dacile one-pot synthesis of 2,4,5-triarylimidazoles from benzil/ benzoin and aromatic aldehydes显示文摘 | MOHAMMED A F KOKARE N D SANGSHETTI J N | 2007 | Journal of the Korean Chemical Society2007，51，5： | 1 |
| 10 | One-pot efficient synthesis of 2-Aryl-1-arylmethyl-1H-benzimidazoles and 2,4,5-triaryl-1H-imidazoles using oxalic acid catalyst显示文摘 | NAGNNATH D KOKARE JAIPRAKASH N SANGSHETTI DEVANAND B SHINDE | 2007 | Synthesis2007，18，： | 1 |
| 11 | Synthesis of novel3-(1-(1-substituted piperidin-4-yl)-1H-1,2,3-triazol-4-yl)-1,2,4-oxadiazol-5(4H)-one as antifungal agents显示文摘 | Sangshetti JN Nagawade RR Shinde DB | 2009 | Bioorg Med Chem Lett2009，19，13： | 1 |
| 12 | One-pot efficient synthesis of 2-aryl-l-arylmethyl-lH-benzimidazoles and 2,4, 5-triaryl-1H-imidazoles using oxalic acid catalyst显示文摘 | Kokare N D Sangshetti J N Shinde D B | 2007 | Synthesis2007，，18： | 1 |
| 13 | Synthesis of some novel 3-(1-(1- substit utedpiperidin-4-yl) -1 H-l, 2,3-triazol-4-yl) -5-substit uted phenyl-l,2,4-oxadiazoles as antifungal agents显示文摘 | Sangshetti J N Shinde D B | 2011 | Eur J Med Chem2011，46，： | 1 |
| 14 | Microwave assis- ted one pot synthesis of some novel 2,5-disubstituted 1,3,4- oxadiazoles as antifungal agents显示文摘 | Sangshetti J N Chabukswar A R Shinde D B | 2011 | Bioorg Med Chem Lett2011，21，： | 1 |
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