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| 1 | Consumer Perception of Ge?netically Modified Food: Empirical Evidence from India显示文摘 | Mandal Santanu and Rik Paul | 2012 | Journal of International Food & Agribusiness Marketing2012，24，： | 1 |
| 2 | Constructing a multi-objective measure of research performance显示文摘 | Nag paul P S Santanu Boy | 2003 | Scientometrics2003，56，3： | 1 |
| 3 | A Visual Information Management System for the Interactive Retrieval of Faces显示文摘 | Jeffrey Bach Santanu Paul Ramesh Jain | 1993 | IEEE Transactions on Knowledge and Data Engineering1993，5，： | 1 |
| 4 | Identification of a sulfonoquinovosyldiacylglyceride from Azadirachta indica and studies on its cytotoxic activity and DNA binding properties显示文摘 | Ratna Chatterjee Omkar Singh Lalawmpuii Pachuau Shiba Prasad Malik Mausumi Paul Kakali Bhadra Santanu Paul Gopinatha Suresh Kumar Nirup Bikash Mondal Sukdeb Banerjee | 2010 | Bioorganic & Medicinal Chemistry Letters2010，，22： | 1 |
| 5 | Targeting the Bcl-2 family for cancer therapy显示文摘 | Shibu Thomas Bridget A Quinn Swadesh K Das Rupesh Dash Luni Emdad Santanu Dasgupta Xiang-Yang Wang Paul Dent John C Reed Maurizio Pellecchia Devanand Sarkar Paul B Fisher | 2013 | Expert Opinion on Therapeutic Targets2013，，1： | 1 |
| 6 | Targeting the Bcl-2 family for cancer therapy显示文摘 | Shibu Thomas Bridget A Quinn Swadesh K Das Rupesh Dash Luni Emdad Santanu Dasgupta Xiang-Yang Wang Paul Dent John C Reed Maurizio Pellecchia Devanand Sarkar Paul B Fisher | 2013 | Expert Opinion on Therapeutic Targets2013，，1： | 1 |
| 7 | Recent developments in the asymmetric synthesis and functionalization of symmetrical and unsymmetrical gem-diborylalkanes显示文摘gem-Diborylalkanes are an important class of organoboron compounds as they function as a key building block in organic synthesis.In the last decade,there has been growing interest in the enantioselective synthesis of gem-diborylalkanes to access a sp^(3) chiral center with two functionalizable groups.This review summarizes the recent development of the enantioselective synthesis of gem-diborylalkanes and their application in asymmetric synthesis. | Swagata Paul Kanak Kanti Das Debasis Aich Samir Manna Santanu Panda | 2022 | Organic Chemistry Frontiers2022，9，3： | 0 |
| 8 | Two novel compounds, ergosterol and ergosta-5,8-dien-3-ol, from Termitomyces heimii Natarajan demonstrate promising antihepatocarcinoma activity显示文摘Background:Mushroom-derived components have immense potential to become a safe alternative in identifying lead anti-cancer molecules.Termitomyces heimii Natarajan(T.heimii)is a traditionally used edible mushroom with no previous record of anti-hepatocarcinoma activity.Methods:The anti-proliferative efficacy of the mushroom ethyl acetate extract was screened against a panel of seven cancer cell lines,namely Hep G2,MCF-7,MDA-MB-231,MAD-MB-436,MOLT-4,Reh,and K-562,and against peripheral blood mononuclear cells isolated from normal healthy donors by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide reduction assay.The impact of the extract on nuclear morphology was examined by 40,6-diamidino-2-phenylindole staining and the apoptotic potential of the extract was evaluated through flow cytometry and Annexin V-PI dual staining,followed by an in vitro scratch assay to elucidate the anti-migratory potential of the extract.The apoptotic and antimigratory effects were further validated using in silico molecular docking with four compounds,ergosterol,ergosta-5,8-dien-3-ol,lanosterol,and eburicol,against two anti-apoptotic proteins,Bcl-2 and Bcl-XL,and two angiogenic receptors,VEGFR-1 and VEGFR-2.Results:The screening data revealed that ethyl acetate extract exhibited remarkable anti-proliferative efficacy against Hep G2 cells,with a half maximal inhibitory concentration(IC50)value of 263.53(8.09)mg/mL,followed by MCF-7 cell lines and showed a negligible effect on peripheral blood mononuclear cells.A clear alteration of the cellular and nuclear morphology was concentration-dependently observed in Hep G2 cells.The extract induced robust apoptosis and a significant concentrationdependent increase in the scratch area.The results of in silico docking revealed that compared to standard drug sunitinib,both ergosterol and ergosta-5,8-dien-3-ol displayed lower binding energy,and satisfactory drugability and absorption,distribution,metabolism,excretion,and toxicity properties.Conclusions:T.heimii is a potential source for isolating lead anticancer molecules in the future.Ergosterol and ergosta-5,8-dien-3-ol hold great promise as new drugs against hepatocarcinoma. | Ribhu Ray Saparja Saha Santanu Paul | 2022 | Journal of Traditional Chinese Medical Sciences2022，9，4： | 0 |
| 9 | Novel wild edible mushroom Astraeus hygrometricus(Pers.)Morgan induces robust apoptosis on human acute lymphoblastic leukemia cells through a RONS-subsisted mitochondria-dependent pathway显示文摘Objective:To explore the therapeutic effects of the novel wild edible mushroom Astraeus hygrometricus(Pers.)Morgan(A.hygrometricus)on human acute lymphoblastic leukemia cells.Methods:Extensive screening of the antiproliferative and chemopreventive potential of different extracts from 5 wild mushrooms,A.hygrometricus,Phallus sp.,Lentinus sp.,Tricholoma sp.,and Serpula sp.was performed against a panel of 6 cancer cell lines and normal cells using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay.Apoptosis determination,cell cycle profiling,intracellular reactive oxygen species(ROS)and reactive nitrogen species(RNS),and mitochondrial membrane potential were analyzed by flow cytometry.The activity of caspases was measured colorimetrically,and the expression pattern of mitochondrial proteins was analyzed.Results:The methanol extract of A.hygrometricus and MOLT-4 cells were identified as the most potent extract exhibiting antiproliferative activity and most sensitive cell line,respectively.The mushroom extract induced robust selective apoptosis in MOLT-4 cells and arrested cell cycle progression at the G0/G1 stage.The extract disrupted the mitochondrial membrane potential and enhanced ROS production in MOLT-4 cells.The methanol extract induced apoptosis by downregulating the expression of Bcl-2,increasing the expression of Bax,and activating the caspase cascade.Conclusion:The novel wild edible mushroom is a potential repository of biomolecules for the development of antileukemic drugs. | Amrita Pal Ribhu Ray Anirban Chouni Subhadip Hajra Santanu Paul | 2024 | Journal of Traditional Chinese Medical Sciences2024，11，1： | 0 |
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