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| 1 | Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration显示文摘AIM: To evaluate the diagnostic accuracy of endoscopic ultrasound-guided fi ne-needle aspiration (EUS-FNA) for pancreatic solid tumors larger or smaller than 3 cm, and cystic lesions. METHODS: From January/1997 to December/2006, 611 patients with pancreatic tumors were subjected to EUS-FNA. The fi nal diagnosis was obtained either by surgery (356 cases) or after a mean clinical follow-up of 11.8 mo in the remaining patients. RESULTS: There were 405 solid tumors, 189 cystic lesions and 17 mixed. Pancreatic specimens for cytological assessment were successfully obtained by EUS-FNA in 595 (97.4/) cases. There were 352 (57.6/) malignancies and 259 (42.4/) benign tumors. Among the malignancies, pancreatic adenocarcinomas accounted for 67/ of the lesions. Overall, the sensitivity, specifi city, positive and negative predictive values, and accuracy of EUS-FNA were, respectively, 78.4/, 99.2/, 99.3/, 77.2/ and 87.2/. Specif ically for solid tumors, the same parameters for neoplasms larger and smaller than 3 cm were, respectively, 78.8/ vs 82.4/, 100/ vs 98.4/, 100/ vs 99/, 54.8/ vs 74.1/ and 83.1/ vs 87.8/. For cystic lesions, the values were, respectively, 72.2/, 99.3/, 97.5/, 91/ and 92.2/. CONCLUSION: EUS-FNA can be used to sample pancreatic tumors in most patients. Even though the negative predictive value is inadequate for large solid tumors, the results are rather good for small solid tumors, especially concerning the sensitivity, negative predictive value and diagnostic accuracy. Among all pancreatic lesions, EUS-FNA for cystic lesions canreveal the best negative predictive value and diagnostic accuracy, both higher than 90/. | José Celso Ardengh César Vivian Lopes Luiz Felipe Pereira de Lima Juliano Rodrigues de Oliveira Filadélfi o Venco Giulio Cesare Santo José Luiz Pimenta Módena | 2007 | World Journal of Gastroenterology2007，13，22： | 17 |
| 2 | Non-ST elevation acute coronary syndrome in the elderly显示文摘1 Introduction Societies are ageing at an accelerated pace.This scenario is a well-known challenge for health care systems,as chronic diseases,multiple comorbidities and dependency are all entities that often converge in the elderly.Besides,there is an issue regarding a reduction in the general incidence of acute coronary syndrome(ACS)together with a delayed in the age of presentation,which,in sum,lead to an increase in both incidence and prevalence of ACS with age,especially non-ST elevation myocardial infarction(NSTEMI). | Pablo Díez-Villanueva César Jiménez Méndez Fernando Alfonso | 2020 | Journal of Geriatric Cardiology2020，17，1： | 4 |
| 3 | Radiation damping optical enhancement in cold atoms显示文摘The typically tiny effect of radiation damping on a moving body can be amplified to a favorable extent by exploiting the sharp reflectivity slope at one edge of an optically induced stop-band in atoms loaded into an optical lattice.In this paper,this phenomenon is demonstrated for the periodically trapped and coherently driven cold 87Rb atoms,where radiation damping might be much larger than that anticipated in previous proposals and become comparable with radiation pressure.Such an enhancement could be observed even at speeds of only a few meters per second with less than 1.0%absorption,making radiation damping experimentally accessible. | Jin-Hui Wu SAR Horsley M Artoni GC La Rocca | 2013 | Light(Science & Applications)2013，2，1： | 3 |
| 4 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 5 | Current trends of liver cirrhosis in Mexico: Similitudes and differences with other world regions显示文摘AIM To investigate the main current etiologies of cirrhosis in Mexico.METHODS We performed a cross-sectional retrospective multicenter study that included eight hospitals in different areas of Mexico. These hospitals provide health care to people of diverse social classes. The inclusion criteria were a histological, clinical, biochemical, endoscopic, or imaging diagnosis of liver cirrhosis. Data were obtained during a 5-year period(January 2012-December 2017). RESULTS A total of 1210 patients were included. The mean age was 62.5 years(SD = 12.1), and the percentages of men and women were similar(52.0% vs 48.0%). The most frequent causes of liver cirrhosis were hepatitis C virus(HCV)(36.2%), alcoholic liver disease(ALD)(31.2%), and nonalcoholic steatohepatitis(23.2%), and the least frequent were hepatitis B virus(1.1%), autoimmune disorders(7.3%), and other conditions(1.0%).CONCLUSION HCV and ALD are the most frequent causes of cirrhosis in Mexico. However, we note that non-alcoholic fatty liver disease(NAFLD) as an etiology of cirrhosis increased by 100% compared with the rate noted previously. We conclude that NAFLD will soon become one of the most frequent etiologies of liver cirrhosis in Mexico. | Nahum Méndez-Sánchez Felipe Zamarripa-Dorsey Arturo Panduro Emma Purón-González Edgar Ulises Coronado-Alejandro Carlos Alejandro Cortez-Hernández Fátima Higuera de la Tijera José Luis Pérez-Hernández Eira Cerda-Reyes Heriberto Rodríguez-Hernández Vania César Cruz-Ramón Oscar Lenin Ramírez-Pérez Nancy Edith Aguilar-Olivos Olga Fabiola Rodríguez-Martínez Samantha Cabrera-Palma Guillermo Cabrera-álvarez | 2018 | World Journal of Clinical Cases2018，6，15： | 2 |
| 6 | Clinical significance of'anti-HBc alone'in human immunodeficiency virus-positive patients显示文摘AIM:To determine the prevalence and clinical relevance of isolated antibodies to hepatitis B core antigen as the only marker of infection('anti-HBc alone')among human immunodeficiency virus(HIV) type-1 infected patients.Occult hepatitis B infection frequency was also evaluated. METHODS:Three hundred and forty eight histories from 2388 HIV-positive patients were randomly reviewed.Patients with serological markers of hepatitis B virus(HBV)infection were classified into three groups:past hepatitis,'anti-HBc alone'and chronic hepatitis.Determination of DNA from HBV,and RNA and genotype from hepatitis C virus(HCV)were performed on'anti-HBc alone'patients. RESULTS:One hundred and eighty seven(53.7%) HIV-positive patients had markers of HBV infection: 118 past infection(63.1%),14 chronic hepatitis (7.5%)and 55'anti-HBc alone'(29.4%).Younger age[2.3-fold higher per every 10 years younger;95% confidence intervals(CI)1.33-4.00]and antibodies to HCV infection[odds ratio(OR)2.87;95%CI 1.10-7.48]were factors independently associated with the'anti-HBc alone'pattern.No differences in liver disease frequency were detected between both groups. Serum levels of anti-HBs were not associated with HCV infection(nor viral replication or HCV genotype),or with HIV replication or CD4 level.No'anti-HBc alone' patient tested positive for HBV DNA. CONCLUSION:'Anti-HBc alone'prevalence in HIVpositive patients was similar to previously reported data and was associated with a younger age and with antibodies to HCV infection.In clinical practice,HBV DNA determination should be performed only in those patients with clinical or analytical signs of liver injury. | M~aTeresa Pérez-Rodríguez Bernardo Sopea Manuel Crespo Alberto Rivera Teresa González del Blanco Antonio Ocampo César Martínez-Vázquez | 2009 | World Journal of Gastroenterology2009，15，10： | 2 |
| 7 | Surgical treatment of distal intraar-ticular humeral fractures in adults显示文摘 | Eralp L Kocaoglu M Sar C | 2001 | Int Orthop2001，25，： | 1 |
| 8 | Dose dependent alteraton in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate 显示文摘 | Lehmann K P Phillips S Sar M | 2004 | Toxicol Sci2004，81，： | 1 |
| 9 | Effect of high pressure processing on the quality of acidified Granny Smith apple puree product显示文摘 | Landl A Abadias M Sar~aga C | 2010 | Innovative Food Science and Emerging Technologies2010，11，： | 1 |
| 10 | Carbon Dots-Doped Electrospun Fibers for Simultaneous Metal Ion Detection and Adsorption of Dyes显示文摘The required treatment and monitoring of contaminants in wastewater reinforces the development of low-cost adsorbents/chemosensors,introducing advantages relative to the detection/removal of toxic metals and dyes.Herein,it is reported a two-step process of fabrication of fluorescent carbon dots via the hydrothermal treatment of amino acids for the following encapsulation in electrospun fibers.The prominent anionic behavior of electrospun fibers of Eudragit L100 was explored for adsorption of cationic dyes(methylene blue and crystal violet)-with the prevailing electrostatic interaction of parts being favored by the formation of monolayers on the surface of adsorbents.On the other hand,the controlled release of carbon dots(CDs)from fibers to the reactor can be explored for a second application:the nitrogen ligands from released glycine-based carbon dots can be explored to indicate the presence of metal ions in aqueous solution.Our experiment resulted in a quenching in the fluorescence of the CDs in order of 90%in the emission of particles in the response of the presence of Fe^(3+) ions,characterizing a promising perspective for this experimental system. | Mário César A.de Oliveira Elisângela G.de L.Oliveira Indira C.B.Pires Iuri C.M.Candido Nikifor Rakov Helinando P.de Oliveira Yutao Xing Glauco S.Maciel | 2020 | Advanced Fiber Materials2020，2，6： | 1 |
| 11 | Surgical treatment of distal intraarticular humeral fractures in adults 显示文摘 | Eralp L Kocaoglu M Sar C | 2001 | Iht Orthop2001，25，1： | 1 |
| 12 | Olfactory mu coscellnecrosis in male CD rats following acute inhalation exposure to hyd ro gensulfide:revers ib ility and the poss iblerole of regionalm etabolism显示文摘 | Brenneman KA Meleason DF Sar M | | 0，，： | 1 |
| 13 | Interactions between arbuscular mycorrhizal fungi and other microbial inoculants (Azospirillum, Pseudomonas, Trichoderma) and their effects on microbial population and enzyme activities in the rhizosphere of maize plants 显示文摘 | Mar Vázquez M César S Azcón R | 2000 | Applied Soil Ecology2000，15，： | 1 |
| 14 | On certain pairs of functions of semiprime rings显示文摘 | | 1994 | Proc Amer Math Soc1994，120，： | 1 |
| 15 | Differential expression of estrogen receptor-α and estrogen receptor-β in the rat ovary显示文摘 | Sar M Welsch F | 1999 | Endocrinology1999，140，： | 1 |
| 16 | MMP-2,TIMP-2 and CD44v6 expression in non-small-cell lung carcinomas 显示文摘 | Eren B Sar M Oz B | 2008 | Ann Acad Med Singapore2008，37，1： | 1 |
| 17 | Histopathologic features aid in predicting risk for progression of IgA nephropathy显示文摘 | Walsh M Sar A Lee D | | 0，，： | 1 |
| 18 | MMP-2, TIMP-2 and CD44v6 expression in non-smallcell lung cancer显示文摘 | Eren B Sar M Oz B | 2008 | Ann Aead Med Sinqapore2008，37，1： | 1 |
| 19 | The human glucocorticoid receptor beta isoform:expression,biochemical properties,and putative function显示文摘 | Oakley RH Sar M Cidlowski JA | 1966 | J Biol Chem1966，271，16： | 1 |
| 20 | Pyrolysis of high-density polyethylene in free-fall reactors in series显示文摘 | Jose' F M Ce'sar B Jesu's C | 2006 | Energy & Fuels2006，20，： | 1 |
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