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| 1 | Hemoglobin A1c in early postpartum screening of women with gestational diabetes显示文摘AIM:To assess the utility of hemoglobin A1c(HbA1c) in the early postpartum screening of women with gestational diabetes mellitus(GDM).METHODS:Over a 3 years period,HbA1c estimations were undertaken in addition to and simultaneously with the traditional oral glucose tolerance test(OGTT),in 203 women with GDM as a part of early postpartum screening for dysglycaemia,at 6 wk post-partum.World Health Organization criteria was used for diagnosing diabetes:fasting blood glucose(FBG) ≥ 7.0 mmol/Land/or 2-h postprandial blood glucose(PPBG) ≥ 11.1 mmol/L and/or HbA1c ≥ 48 mmol/mol;and impaired glycaemiastate:impaired fasting glucose 6.1-6.9 mmol/L and/or impaired glucose tolerance 7.8-11.0 mmol/L and/or HbA1c:42-47 mmol/mol.RESULTS:Mean FBG,2-h PPBG and HbA1c were 4.9 ± 0.7 mmol/L,5.6 ± 2.0 mmol/L and 38 ± 5 mmol/mol respectively.FBG,2-h PPBG and HbA1c detected 6(3%),7(3.5%) and 11(5.4%) cases of diabetes respectively,and 11(5.4%),25(12.3%) and 23(11.3%) cases of pre-diabetes state respectively.HbA1c values ≥ 48 mmol/mol(≥ 6.5%) showed a diagnostic sensitivity of 71.4% and specificity of 98.5% for diabetes in comparison to OGTT in receiver operating characteristics curve analysis.At HbA1c cut-off 44 mmol/mol,sensitivity and specificity were 100% and 92.3% respectively [area under the curve:0.98(95%CI:0.96-1.00)].Sensitivity and specificity for detecting high risk 'impaired glycaemia' state [HbA1c 42 mmol/mol(6.0%)] were 28% and 80%,respectively.CONCLUSION:HbA1c level ≥ 48 mmol/mol(≥ 6.5%) has reasonable sensitivity and high specificity in comparison to OGTT for early postpartum screening of diabetes in GDM.At 6 th week postpartum screening,if FBG is normal and HbA1c < 44 mmol/mol OGTT is not recommended. | Mahesh V Katreddy Joseph M Pappachan Sarah E Taylor Radha Indusekhar Ananth U Nayak Alan M Nevill | 2013 | World Journal of Diabetes2013，4，3： | 2 |
| 2 | Accruals quality and internal control over/inancial reporting显示文摘 | JEFFREY T D GE Weili SARAH M V | 2007 | The Accounting Review2007，82，5： | 1 |
| 3 | Microbial population changes during bioremediation of an experi- mental oil spill显示文摘 | SARAH J M JOHN R S ALBERT D V | 2001 | Applied and Environmental Microbio- logy2001，67，5： | 1 |
| 4 | X-Chromosome monosomy in an infertile female llama显示文摘 | Sarah E Horin D V M | 1997 | J Am Vet Med Assoc1997，210，10： | 1 |
| 5 | Determination of polysorbate 80 in parenteral formulations by high-performance liquid chromatography and evaporative light scattering detection显示文摘 | Lakshmy M Nair Norma V Stephens Sarah V | 2003 | J Chromatogr A2003，1012，1： | 1 |
| 6 | The impact of land use on soil carbon in Miombo woodlands of Malawi显示文摘 | Sarah M W Paul V D | 2004 | Forest Ecology and Management2004，203，13： | 1 |
| 7 | The Disclosure of Material Weaknesses in Inter- nal Control After The Sarbanes-Oxley Act显示文摘 | Weili G Sarah M V | 2005 | Accounting Horizons2005，19，3： | 1 |
| 8 | X - Chromosome Monosomy in an Infertile Female Llama显示文摘 | Katrin Hinrichs Sarah E Horin D V M | 1997 | Journal of the American Veterinary Medical Association1997，210，： | 1 |
| 9 | The impact of land use on soil carbon in Miombo Woodlands of Malawi显示文摘 | Sarah M W Paul V D | 2004 | Forest Ecology and Manage- ment2004，203，13： | 1 |
| 10 | Pancreatic exocrine insufficiency after pancreaticoduodenectomy: Current evidence and management显示文摘Pancreaticoduodenectomy(PD)is the commonest procedure performed for pancreatic cancer.Pancreatic exocrine insufficiency(PEI)may be caused or exacerbated by surgery and remains underdiagnosed and undertreated.The aim of this review was to ascertain the incidence of PEI,its consequences and management in the setting of PD for indications other than chronic pancreatitis.A literature search of databases(MEDLINE,EMBASE,Cochrane and Scopus)was carried out with the MeSH terms“pancreatic exocrine insufficiency”and“Pancreaticoduodenectomy”.Studies that analysed PEI and its complications in the setting of PD for malignant and benign disease were included.Studies reporting PEI in the setting of PD for chronic pancreatitis,conference abstracts and reviews were excluded.The incidence of PEI approached 100%following PD in some series.The pre-operative incidence varied depending on the characteristics of the patient cohort and it was higher(46%-93%)in series where pancreatic cancer was the predominant indication for surgery.Variability was also recorded with regards to the method used for the diagnosis and evaluation of pancreatic function and malabsorption.Pancreatic enzyme replacement therapy is the mainstay of the management.PEI is common and remains undertreated after PD.Future studies are required for the identification of a welltolerated,reliable and reproducible diagnostic test in this setting. | Adithya M Pathanki Joseph A Attard Elizabeth Bradley Sarah Powell-Brett Bobby V M Dasari John R Isaac Keith J Roberts Nikolaos A Chatzizacharias | 2020 | World Journal of Gastrointestinal Pathophysiology2020，11，2： | 1 |
| 11 | Determination of polysorbate 80 in parenteral formulations by high-performance liquid chromatography and evaporative light scattering detection 显示文摘 | Lakshmy M Nair Norma V Stephens Sarah Vincent | 2003 | Journal of Chromatography A2003，1012，： | 1 |
| 12 | Identifica- tion and characterization of flowering genes in ki- wifruit: sequence conservation and role in kiwifruit flower development显示文摘 | Erika V G Sarah M M Charlotte V | 2011 | BMC plant biology2011，11，1： | 1 |
| 13 | The impact of land use on soil carbon in Miombo Woodlands of Malawi显示文摘 | Sarah M W Paul V D | 2004 | Forest Ecology and Management2004，203，： | 1 |
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