维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

1篇 您的检索式：作者名="Sarah Winks"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	Liver cancer understaging in liver transplantation in the current era of radiologic imaging and newer generation locoregional therapies显示文摘Background:Discordance in hepatocellular carcinoma(HCC)staging between pre-transplant imaging and explant pathology is associated with an increased risk of recurrence and death.Our aim was to evaluate variables that predicted concordance/discordance in the era of new generation locoregional therapies(LRT)and improved radiologic technology in diagnosis.Methods:A single-center retrospective study was performed on patients who received a liver transplant for HCC between 2008-2019.Pre-and post-LT variables,including type of LRT,downstaging(DS),transplant time period,and radiologic response to LRT,were analyzed for concordance/discordance.Kaplan-Meier analysis was used to assess post-LT survival.Results:Of 146 patients transplanted within Milan Criteria(MC),discordance rates(understaged)were 45%.Discordance was associated with≥3 HCC lesions at diagnosis but not newer generation LRT(transarterial radioembolization/stereotactic body radiation therapy),traditional LRT or combination.No differences in discordance were seen between transplant periods(2008-2013 vs.2014-2019),but those within MC in the earlier period had higher concordance rates.A trend was observed between DS and discordance.Conclusion:HCC stage discordance remains common and poorly predictable.Discordance was associated with three or more HCC lesions at the time of diagnosis.Patients within MC transplanted between 2008-2013 was associated with concordance,while a trend was noted between DS and discordance.No other pre-or post-LT variables predicted discordance/concordance.Discordance was associated with decreased survival.	Hannah M.Lee Donna McClish Binu V.John Sarah Winks Ryan Clayton Somaya Albhaisi Allawy Allawy Samarth Patel Emma C.Fields Scott Matherly Brian Strife Chandra Bhati Amit Sharma Richard K.Sterling	2022	Hepatoma Research2022，8，1：	0

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费