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| 1 | 某印尼低品位红土镍矿的微观结构及晶体化学(英文)显示文摘为深入研究红土镍矿的镍富集原理,利用电子显微镜、扫描电镜、X射线衍射分析以及电子探针微区分析对含镍0.97%的某印尼低品位红土镍矿的工艺矿物学进行研究,以了解镍钴有价金属的分布及赋存状态。实验表明:该矿样主要矿物为针铁矿(含量约为80%),镍含量约为0.87%;含镍、铁、镁的结晶水硅酸盐矿物((Mg,Fe,Ni)2SiO4)的含量约为15%,如利蛇纹石((Fe,Ni,Al)O(OH))和橄榄石((Mg,Fe,Ni)3Si2O5(OH))等,镍含量约在1.19%左右;其它含量较低的物相为赤铁矿、磁赤铁矿、铬铁矿和石英等,这些矿物的镍含量极低。钴土矿是含钴矿物,分析发现该矿物往往有较高的镍和钴含量。微观检测发现:红土镍矿微观结构复杂,不同矿物之间共生普遍,主要矿物的微观结构松散,因而传统选矿方式很难实现镍的富集。 | 朱德庆 崔瑜 Sarath HAPUGODA Keith VINING 潘建 | 2012 | Transactions of Nonferrous Metals Society of China2012，22，4： | 8 |
| 2 | 罗氏沼虾几丁质酶3B基因的克隆及其在蜕皮周期中的表达显示文摘罗氏沼虾的生长发育及繁殖都与蜕皮紧密相关。几丁质酶是甲壳动物在蜕皮过程中最重要的酶之一。本研究对罗氏沼虾蜕皮周期外观特征和腹肢刚毛进行了观察描述,克隆并分析了罗氏沼虾的几丁质酶Ⅲ基因(MrChi3B),制备了几丁质酶Ⅲ蛋白的多克隆抗体,研究了其在蜕皮周期中的表达。罗氏沼虾几丁质酶基因cDNA的开放阅读框为1 143 bp,编码380个氨基酸,大小为41.91 ku。通过氨基酸序列比对发现,MrChi3B与日本沼虾几丁质酶基因(Chi3B)的同源性最高,为94%。MrChi3B含有一个糖苷键水解酶家族18的催化域。实时定量PCR (qRT-PCR)和蛋白印迹法(WB)检测结果显示,MrChi3B在罗氏沼虾多个组织中均有表达,但是不同组织中的表达有差异。在蜕皮期之后,其在胃、表皮和肌肉中的表达量显著上升。在胃中其表达量在蜕皮间期达到最高;在表皮和肌肉中其表达量在蜕皮后期达到最高;肠中的表达量在蜕皮前期和蜕皮期有所上升;眼柄期的表达量在所有蜕皮期都偏低。本研究结果为进一步研究几丁质酶的功能提供参考依据。 | 叶成凯 卢志杰 Sarath Babu V 张晓君 刘晓丹 赵丽娟 潘淦 林蠡 | 2019 | 水产学报2019，43，4： | 6 |
| 3 | Hepatoprotective activity of Terminalia paniculata against paracetamol induced hepatocellular damage in Wistar albino rats显示文摘Objective:To evaluate the hepatoprotective activity of Terminalia paniculata against paracetamol induced hepatic damage in rats.Methods:The plant material was shade dried, powdered and extracted with ethanol.Liv 52 and silymarin were used as standard drugs and 2%gum acacia as a control(vehicle).Alteration in the levels of biochemical markers of hepatic damage like AST,ALT,ALP and lipid peroxides were tested,and phytochemical tests were also performed.Results:Paracetamol(2 g/kg) increased the serum levels of alanine aminotransfer (ALT),aspartate aminotransferase(AST),alkaline phosphatase(ALP) and the lipid peroxides. Treatment of Liv 52,silymarin and ethanolic extract of Terminalia paniculata(200 mg/kg) altered levels of biochemical marker and showed significant hepatoprotective activity.Ethanolic extract revealed the presence of phenolic compound and flavanoids.Our findings suggested that ethanolic bark extract of Terminalia paniculata possessed hepatoprotective activity in a dose dependent manner.Conclusions:Terminalia paniculata possesses hepatoprotective activity.It could be an effective and promising preventive agent against PCT induced hepatotoxicity. | Eesha BR Mohanbabu Amberkar V Meena Kumari K Sarath babu Vijay M Lalit M Rajput R | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，6： | 5 |
| 4 | 罗氏沼虾谷氨酰胺合成酶基因的克隆与表达显示文摘谷氨酰胺合成酶(glutamine synthetase, GS)是一种广泛分布在动植物体内的酶,并参与细胞多种代谢调控。在甲壳动物中,GS在能量代谢和渗透压调节过程中起着重要作用。实验克隆了罗氏沼虾GS基因。GS基因cDNA全长1 965 bp,开放读码框(ORF)为1 086 bp,编码361个氨基酸(aa),分子量大小为40.75 ku,等电点为5.81。进化树分析发现,罗氏沼虾GS基因与凡纳滨对虾、斑节对虾和中国明对虾GS聚为一支,氨基酸相似性达到95%。氨基酸多序列比对分析结果显示,罗氏沼虾GS属于无脊椎动物分支的GSⅡ群,有5个保守区域。实验对罗氏沼虾GS蛋白进行表达并制备了多克隆抗体。采用荧光定量PCR技术(qRT-PCR)和免疫印迹(Western blot)对罗氏沼虾蜕壳前后的不同组织GS表达进行检测。qRT-PCR结果显示,GS基因在所检测的8个组织中均有表达;蜕壳前,其相对表达量顺序为:肝胰脏>肌肉>胃>肠>鳃>心脏>脑>血淋巴。蜕壳后和蜕壳前GS基因在组织中的差异表达比较结果显示,除了在肝胰脏表达下调外,其他7个组织都表达升高,其相对表达量的差异顺序为:脑>鳃>胃>肠>肌肉>心脏>血淋巴。Westernblot结果显示,蜕壳后GS蛋白在鳃和肌肉组织表达量上调,与其mRNA表达一致。此外,罗氏沼虾蜕壳后肝胰脏GS酶的活性和谷氨酰胺的含量下调,而其在鳃、肌肉和血淋巴中上调,结果与其基因表达一致。研究表明,GS基因在不同组织中表达的差异可能和罗氏沼虾的能量代谢、渗透压调节有关。 | 卢志杰 叶成凯 Sarath Babu V 张晓君 刘晓丹 赵丽娟 潘淦 林蠡 | 2019 | 水产学报2019，43，3： | 5 |
| 5 | Wound healing activity of aqueous extract of Crotalaria verrucosa in Wistar albino rats显示文摘Objective:To evaluate the wound healing effect of aqueous extract of Crotalaria verrucosa(C. verrucosa) in rats.Methods:Three wound models including incision,excision and dead space wounds were used in this study.The parameters studied were breaking strength in incision models,granulation tissue dry weight,breaking strength and hydroxyproline content in dead space wounds,percentage of wound contraction and period of epithelialization in excision wound model.Results:Two doses of the extract with and without dexamethasone showed significant increases in mean hydroxyproline,total protein content and dry weight of granulation tissue but it was higher with dose 800 mg/kg comparing with the control.The dexamethasone treated group showed a significant(P<0.001) reduction in the wound breaking strength when compared to control group in incision type of wound model.Coadministration of C.verrucosa with dexamethasone significantly(P<0.001) increased the breaking strength compared to the dexamethasone treated only group.In excision wound model,the percentage of the wound contraction was significantly(P<0.01) increased by two doses of test extract on all the days except the lower dose which exhibited only on 12th,16th days of drug treatment and it also reversed the dexamethasone suppressed wound contraction.It significantly(P<0.001) reduced the time required for epithelialization and reversed the epithelialization delaying effect of dexamethasone (P<0.001).Conclusions:C.verrucosa was found to possess significant wound healing property. This was evident by decrease in the period of epithelialization,increase in the rate of wound contraction,skin breaking strength,and granulation tissue dry weight content.Hence C. verrucosa could be a good wound healing agent. | Meena Kumari Eesha BR Mohanbabu Amberkar Sarath babu Rajshekar Neelesh Kumar | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，10： | 3 |
| 6 | Performant implementation of the atomic cluster expansion(PACE)and application to copper and silicon显示文摘The atomic cluster expansion is a general polynomial expansion of the atomic energy in multi-atom basis functions.Here we implement the atomic cluster expansion in the performant C++code PACE that is suitable for use in large-scale atomistic simulations.We briefly review the atomic cluster expansion and give detailed expressions for energies and forces as well as efficient algorithms for their evaluation.We demonstrate that the atomic cluster expansion as implemented in PACE shifts a previously established Pareto front for machine learning interatomic potentials toward faster and more accurate calculations.Moreover,general purpose parameterizations are presented for copper and silicon and evaluated in detail.We show that the Cu and Si potentials significantly improve on the best available potentials for highly accurate large-scale atomistic simulations. | Yury Lysogorskiy Cas van der Oord Anton Bochkarev Sarath Menon Matteo Rinaldi Thomas Hammerschmidt Matous Mrovec Aidan Thompson Gábor Csányi Christoph Ortner Ralf Drautz | 2021 | npj Computational Materials2021，，1： | 3 |
| 7 | Assessment of calcium polysulfide for the remediation of hexavalent chromium in chromite ore processing residue (COPR)显示文摘 | Mahmoud Wazne Santhi Chandra Jagupilla Deok Hyun Moon Sarath Chandra Jagupilla Christos Christodoulatos Min Gyu Kim | 2007 | Journal of Hazardous Materials2007，，3： | 2 |
| 8 | Galvanic corrosion of magnesium alloy AZ91D in contact with an aluminium alloy, steel and zinc显示文摘 | Guangling Song Birgir Johannesson Sarath Hapugoda David StJohn | 2003 | Corrosion Science2003，，4： | 2 |
| 9 | Capacitor Voltage Balancing Strategy Based on Sub-module Capacitor Voltage Estimation for Modular Multilevel Converters显示文摘The modular multilevel converter(MMC)is expected to be used extensively in high-voltage direct current(HVDC)transmission networks because of its superior characteristics over the line-commutated converter(LCC).A key issue of concern is balancing sub-module capacitor voltages in the MMCs,which is critical for the correct operation of these converters.The majority of voltage balancing techniques proposed thus far require that the measurement of the capacitor voltages use a reliable measuring system.This can increase the capital cost of the converters.This paper presents a voltage balancing strategy based on capacitor voltage estimation using the adaptive linear neuron(ADALINE)algorithm.The proposed estimation unit requires only three voltage sensors per phase for the arm reactors and the output phase voltages.Measurements of sub-module capacitor voltages and associated communication links with the central controller are not needed.The proposed strategy can be applied to MMC systems that contain a large number of sub-modules.The method uses PSCAD/EMTDC,with particular focus on dynamic performance under a variety of operating conditions. | Mahmoud Abdelsalam Mostafa Marei Sarath Tennakoon Alison Griffiths | 2016 | CSEE Journal of Power and Energy Systems2016，2，1： | 2 |
| 10 | Development and validation of a HPLC method for the determination of vorieon- azole in pharmaceutical formulation using an experimental de- sign 显示文摘 | Srinubabu G Raju Ch Sarath IV | 2007 | Talanta2007，71，3： | 1 |
| 11 | Investigation of partial discharge activity of single conducting particle in trans- former oil under DC voltages using UHF technique显示文摘 | SARATH R KOPERUNDEVI G | 2009 | IET Science Measurement and Technology2009，3，5： | 1 |
| 12 | Blood compatibility of iron-doped nanosize hydroxyapatite and its drug release显示文摘 | SARATH C V BASKAR G SUGANTHI R V | 2012 | ACS Ap- pl Mater Interfaces2012，4，： | 1 |
| 13 | RInD Reporting Bi- ases and Their Consequences显示文摘 | Lev B Sarath B Sougiannis T | 2005 | Contemporary Ac- counting Research2005，22，4： | 1 |
| 14 | Arsenic causes aortic dysfunc- tion and systemic hypertension in rats: augmentation of angiotensin II signaling显示文摘 | Waghe P Sarath TS Gupta P | 2015 | Chem Biol Interact2015，，237： | 1 |
| 15 | Capability con- straints to mitigate voltage fluctuations from DFIG wind farms when delivering ancillary services to the network 显示文摘 | Lasantha Meegahapola Sarath Perera | 2014 | Electrical Power and Energy Systems2014，，62： | 1 |
| 16 | Ethanol yields and cell wall properties in divergently bred switchgrass genotypes显示文摘 | Sarath G Dien B Sarath A J | 2011 | Bioresource Technology2011，102，： | 1 |
| 17 | Prophylactic antibiotics in open mesh repair of inguinal hernia:a randomized controlled trial 显示文摘 | GOMATHI SHANKAR V SRINIVASAN K SARATH C | 2010 | Int J Surg2010，8，6： | 1 |
| 18 | Two shear deformable finite element models for buckling analysis of skew fiber- reinforced composite and sandwich panels显示文摘 | Sarath Babu C Kant T | 1999 | Com- posite Structures1999，46，2： | 1 |
| 19 | Chitinases from the plant disease biocontrol agent,Stenotrophomonasmaltophilia C3显示文摘 | Zhang Z Yuen G Y Sarath G | 2001 | Phytopathology2001，91，2： | 1 |
| 20 | Biotinylation of K12 in histone I-I4 decreases in response to DNA double- strand breaks in human JAr choriocarcinoma cells 显示文摘 | KOTHAPALLI N SARATH G ZEMPLENI J | 2005 | Journal of Nutrition2005，135，10： | 1 |
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