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| 1 | Study of Helicobacter pylori genotype status in saliva,dental plaques,stool and gastric biopsy samples显示文摘AIM:To compare genotype of Helicobacter pylori(H.pylori) isolated from saliva,dental plaques,gastric biopsy,and stool of each patient in order to evaluate the mode of transmission of H.pylori infection.METHODS:This cross-sectional descriptive study was performed on 300 antral gastric biopsy,saliva,dental plaque and stool samples which were obtained from patients undergoing upper gastrointestinal tract endoscopy referred to endoscopy centre of Hajar hospital of Shahrekord,Iran from March 2010 to February 2011.Initially,H.pylori strains were identified by rapid urease test(RUT) and polymerase chain reaction(PCR) were applied to determine the presence of H.pylori(ureC) and for genotyping of voculating cytotoxin gene A(vacA) and cytotoxin associated gene A(cagA) genesin each specimen.Finally the data were analyzed by using statistical formulas such as Chi-square and Fisher's exact tests to find any significant relationship between these genes and patient's diseases.P < 0.05 was considered statistically significant,RESULTS:Of 300 gastric biopsy samples,77.66% were confirmed to be H.pylori positive by PCR assay while this bacterium were detected in 10.72% of saliva,71.67% of stool samples.We were not able to find it in dental plaque specimens.The prevalence of H.pylori was 90.47% among patients with peptic ulcer disease(PUD),80% among patients with gastric cancer,and 74.13% among patients with none ulcer dyspepsia(NUD) by PCR assay.The evaluation of vacA and cagA genes showed 6 differences between gastric biopsy and saliva specimens and 11 differences between gastric and stool specimens.94.42% of H.pylori positive specimens were cagA positive and all samples had amplified band both for vacA s and m regions.There was significant relationship between vacA s1a/m1a and PUD diseases(P = 0.04),s2/m2 genotype and NUD diseases(P = 0.05).No statically significant relationship was found between cagA status with clinical outcomes and vacA genotypes(P = 0.65).The evaluation of vacA and cagA genes showed 6 differences between gastric biopsy and saliva specimens and 11 differences between gastric and stool specimens,CONCLUSION:Regard to high similarity in genotype of H.pylori isolates from saliva,stomach and stool,this study support the idea which fecal-oral is the main route of H.pylori transmission and oral cavity may serve as a reservoir for H.pylori,however,remarkable genotype diversity among stomach,saliva and stool samples showed that more than one H.pylori genotype may exist in a same patient. | Hassan Momtaz Negar Souod Hossein Dabiri Meysam Sarshar | 2012 | World Journal of Gastroenterology2012，18，17： | 21 |
| 2 | Calculation of HVDC Converter Noncharacteristic Harmonics Using Digital Time Domain Simulation Method显示文摘 | Sarshar A Iravani M R | 1996 | IEEE Trans on Power Delivery1996，11，1： | 1 |
| 3 | Scale-free and stable structures in complex ad hoc networks 显示文摘 | Sarshar N Roychowdhury V | 2004 | Physical Review E2004，69，2： | 1 |
| 4 | Imidazole Libraries on Solid Support 显示文摘 | SARSHAR S SIEV D MJALLI A M M | 1996 | Tetrahedron Letters1996，37，： | 1 |
| 5 | Analysis of harmonic and transient phenomena due to operation of an A-C arc furnace显示文摘 | Sarshar A Sharp M Iravance R M | 1996 | Iron and Steel Engineer1996，73，4： | 1 |
| 6 | On fair and optimal multi- source IP-multicast 显示文摘 | RAHIMI M R BAIS A SARSHAR N | 2012 | Computer Networks2012，56，4： | 1 |
| 7 | Analysis of harmonic and transient phenomena due to operation of an a-c arc fumace显示文摘 | Sarshar A Sharp M Iravane M T | 1996 | Iron and Steel Engineer1996，，： | 1 |
| 8 | Novel oxygen carriers for chemical looping combustion: La1-xCexBO3(B = Co, Mn) perovskitessynthesized by reactive grinding and nanocasting显示文摘 | SARSHAR Z KLEITZ F KALIAGUINE S | 2011 | Energy Environ Sci2011，4，10： | 1 |
| 9 | Multiple power-law structures in heterogeneous complex networks显示文摘 | Sarshar N Roychowdhury V | 2005 | Physical Review E : Statistical Nonlinear and Soft Matter Physics2005，72，26： | 1 |
| 10 | Collaborative spam filtering using E-mail networks显示文摘 | KONG J E REZAEI B A SARSHAR N | 2006 | IEEE Computer2006，39，8： | 1 |
| 11 | Rainbow network flow of multiple description coding显示文摘 | Wu Xiaolin Ma Bin Sarshar N | 2008 | IEEE Transactions on Information Theory2008，54，10： | 1 |
| 12 | The origin of high enantioselectivity in the dihydroxylation of olefins using osmium tetraoxide and cinchona alkaloid catalysts 显示文摘 | Corey E J Noe M C Sarshar S | 1993 | J Am Chem Soc1993，115，9： | 1 |
| 13 | Material and enviromental factors influencing the compressive strength of unsealed cement paste and concrete at high temperature显示文摘 | Sarshar G Khoury A | 1993 | Magazine of concrete research1993，，3： | 1 |
| 14 | Thermal be- havior of a ventilated double skin facade in hot add climate 显示文摘 | Hashemi N Fayaz R Sarshar M | 2010 | Energy and Buildings2010，42，10： | 1 |
| 15 | Collaborative Spam Filtering Using E-mail Networks显示文摘 | Kong J S Rezaei B A Sarshar N | 2006 | IEEE Computer2006，39，08： | 1 |
| 16 | Teterahedron Lett显示文摘 | Sarshar S Siev D Mjalli A M M | 1996 | 37:8351996，37，： | 1 |
| 17 | Collaborative spam filtering using E-mail network显示文摘 | Joseph S Kong Behnam A Rezaei Nima Sarshar | 2006 | IEEE Computer Society2006，39，8： | 1 |
| 18 | Thermal behaviour of a ventilated double skin facade in hot arid climate显示文摘 | N. Hashemi R. Fayaz M. Sarshar | 2010 | Energy & Buildings2010，，10： | 1 |
| 19 | Scale-flee and stable struc- tures in complex ad hoc networks显示文摘 | SARSHAR N ROYCHOWDHURY V | 2004 | Physical Review E2004，69，02： | 1 |
| 20 | Scale-free and stable structures in complex ad hoc networks显示文摘 | SARSHAR N ROYCHOWDHURY V | | 0，，： | 1 |
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