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| 1 | Asynchronous Embryo Transfer in Sheep:Lack of Survival in Progestinized Recipient Ewes显示文摘Synchronization of development between the embryo and uterus is required for successful pregnancy establishment.Transfer of early embryos requires synchrony with the recipient uterus of 2 days or less in sheep,because asynchrony of 3 days or more results in failure of pregnancy recognition signaling for maintenance of corpus luteum (CL) and progesterone (P4) production and/or uterine support of the embryo.The objective was to determine if P4 treatment of recipient ewes would obviate the need for pregnancy recognition signaling and maintain a uterine environment conducive to embryo survival after asynchronous transfer,thereby establishing a universal recipient.Embryos (morulae/blastocysts) were recovered on day 6 from super-ovulated donor ewes.Recipient ewes received 25 mg P4 daily from day 6 post-estrus until 60 days after embryo transfer.Embryos were transferred into recipients on day 6,9,12,18,or 30 post-estrus.The pregnancy rate on day 22 post-transfer was 60% for synchronous transfers to day 6 ewes,44% and 22% for asynchronous transfers to day 9 and 12 ewes,and 0% for asynchronous transfers to day 18 and 30 ewes.On day 39 post-transfer,pregnancy rates remained 60% for day 6 ewes,33% for day 9 ewes,and 0% for day 12,18,and 30 ewes.The P4 treatment did extend the window of uterine receptivity to early embryos in ewes by one day,but did not create a universal recipient.Available results support the idea that a window of uterine receptivity to the conceptus exists in sheep that is independent of pregnancy recognition signaling. | M.Carey Satterfield Thomas E.Spencer | 2011 | Journal of Animal Science and Biotechnology2011，2，1： | 5 |
| 2 | 婴幼儿血管瘤的治疗与管理显示文摘婴幼儿血管瘤(IH)也称为婴幼儿毛细血管瘤、草莓状血管瘤或草莓痣,是儿童中常见的非恶性血管瘤。自然疾病过程通常包括长达1年的生长期,然后在几年内不经治疗而退化,不或少遗留美容或功能性后遗症。 | Satterfield KR Chambers CB 赵泽亮 | 2019 | 中国口腔颌面外科杂志2019，17，2： | 4 |
| 3 | Uterine biology in pigs and sheep显示文摘There is a dialogue between the developing conceptus (embryo-fetus and associated placental membranes) and maternal uterus which must be established during the peri-implantation period for pregnancy recognition signaling, implantation, regulation of gene expression by uterine epithelial and stromal cells, placentation and exchange of nutrients and gases. The uterus provide a microenvironment in which molecules secreted by uterine epithelia or transported into the uterine lumen represent histotroph required for growth and development of the conceptus and receptivity of the uterus to implantation. Pregnancy recognition signaling mechanisms sustain the functional lifespan of the corpora lutea (CL) which produce progesterone, the hormone of pregnancy essential for uterine functions that support implantation and placentation required for a successful outcome of pregnancy. It is within the peri-implantation period that most embryonic deaths occur due to deficiencies attributed to uterine functions or failure of the conceptus to develop appropriately, signal pregnancy recognition and/or undergo implantation and placentation. With proper placentation, the fetal fluids and fetal membranes each have unique functions to ensure hematotrophic and histotrophic nutrition in support of growth and development of the fetus. The endocrine status of the pregnant female and her nutritional status are critical for successful establishment and maintenance of pregnancy. This review addresses the complexity of key mechanisms that are characteristic of successful reproduction in sheep and pigs and gaps in knowledge that must be the subject of research in order to enhance fertility and reproductive health of livestock species. | Fuller W Bazer Gwonhwa Song Jinyoung Kim Kathrin A Dunlap Michael Carey Satterfield Gregory A Johnson Robert C Burghardt Guoyao Wu | 2012 | Journal of Animal Science and Biotechnology2012，3，3： | 3 |
| 4 | Functional roles of ornithine decarboxylase and arginine decarboxylase during the peri-implantation period of pregnancy in sheep显示文摘Background: Polyamines stimulate DNA transcription and m RNA translation for protein synthesis in trophectoderm cells, as well as proliferation and migration of cells; therefore, they are essential for development and survival of conceptuses(embryo/fetus and placenta). The ovine conceptus produces polyamines via classical and non-classical pathways. In the classical pathway, arginine(Arg) is transformed into ornithine, which is then decarboxylated by ornithine decarboxylase(ODC1) to produce putrescine which is the substrate for the production of spermidine and spermine. In the non-classical pathway, Arg is converted to agmatine(Agm) by arginine decarboxylase(ADC), and Agm is converted to putrescine by agmatinase(AGMAT).Methods: Morpholino antisense oligonucleotides(MAOs) were designed and synthesized to inhibit translational initiation of the m RNAs for ODC1 and ADC, in ovine conceptuses.Results: The morphologies of MAO control, MAO-ODC1, and MAO-ADC conceptuses were normal. Double knockdown of ODC1 and ADC(MAO-ODC1:ADC) resulted in two phenotypes of conceptuses; 33% of conceptuses appeared to be morphological y and functional y normal(phenotype a) and 67% of the conceptuses presented an abnormal morphology and functionality(phenotype b). Furthermore, MAO-ODC1:ADC(a) conceptuses had greater tissue concentrations of Agm,putrescine, and spermidine than MAO control conceptuses, while MAO-ODC1:ADC(b) conceptuses only had greater tissue concentrations of Agm. Uterine flushes from ewes with MAO-ODC1:ADC(a) had greater amounts of arginine, aspartate, tyrosine, citrulline, lysine, phenylalanine, isoleucine, leucine, and glutamine, while uterine flushes of ewes with MAO-ODC1:ADC(b) conceptuses had lower amount of putrescine, spermidine, spermine, alanine, aspartate,glutamine, tyrosine, phenylalanine, isoleucine, leucine, and lysine.Conclusions: The double-knockdown of translation of ODC1 and ADC m RNAs was most detrimental to conceptus development and their production of interferon tau(IFNT). Agm, polyamines, amino acids, and adequate secretion of IFNT are critical for establishment and maintenance of pregnancy during the peri-implantation period of gestation in sheep. | Yasser Y.Lenis Gregory A.Johnson Xiaoqiu Wang Wendy W.Tang Kathrin A.Dunlap M.Carey Satterfield Guoyao Wu Thomas R.Hansen Fuller W.Bazer | 2018 | Journal of Animal Science and Biotechnology2018，9，2： | 3 |
| 5 | Product distributions of the Fischer-Tropsch synthesis on precipitated iron catalysts显示文摘 | DONNELLY T J SATTERFIELD C N | 1989 | Appl Catal1989，52，1： | 1 |
| 6 | Catalytic hydrodeoxygenation of dibenzofuran 显示文摘 | Vito La Vopa Charles N Satterfield | 1987 | Energy & Fuels1987，1，4： | 1 |
| 7 | Childhood brain function differences in delinquent and non- delinquent hyperactive boys 显示文摘 | Satterfield J Schell A | 1984 | Electroencephalography Clin Neurophysiol1984，57，： | 1 |
| 8 | Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA-and NF-kappa B-independent mechanisms显示文摘 | Tan KS Nackley AG Satterfield K | 2007 | Cell Signal2007，19，2： | 1 |
| 9 | Topographic study of auditory event-related potentials in normal boys and boys with attention deficit disorder with hyperactivity显示文摘 | Satterfield JH Schell AM Nicholas TW | 1988 | Psychophysiology1988，25，： | 1 |
| 10 | Beta2 adrenergic recep-tor activation stimulates pro-inflammatory cytokine production in mac-rophages via PKA-and NF-kappaB-independent mechanisms显示文摘 | Tan K S Nackley A G Satterfield K | 2007 | Cell Signal2007，19，2： | 1 |
| 11 | Psychosocial aspects of strabismus study显示文摘 | Satterfield D Keltner J L Morrison T L | 1993 | Arch Ophthalmol1993，111，8： | 1 |
| 12 | Poisoning of thiophene hydrodesulfurization by nitrogen compounds显示文摘 | La V V Satterfield C N | | 0，，02： | 1 |
| 13 | Beneficial effects of L-arginine on reducing obesity:potential mechanisms and important implications for human health显示文摘 | McKnight J R Satterfield M C Jobgen W S | 2010 | Amino Acids2010，39，2： | 1 |
| 14 | The power performance curve for engineering analysis of fuel cells显示文摘 | Benziger J B Satterfield M B Hogarth W H J | 2006 | Journal of Power Sources2006，155，2： | 1 |
| 15 | Comparative in vivo activity of gemifloxacin in a rat model of respiratory tract infection 显示文摘 | Berry V Page R Satterfield J | 2000 | J Antimicrob Chemother2000，45，1： | 1 |
| 16 | Intrinsic of the Fischer-Tropsch Synthesis on a Cobalt Catalyst显示文摘 | Yates I C Satterfield C N | 1991 | Energy & Fuels1991，5，： | 1 |
| 17 | Comparative efficacy of gemifloxacin in experimental models of pyelonephritis and wound infection显示文摘 | Berry V Page R Satterfield J | 2000 | J Antimicrob Chemother2000，45，1： | 1 |
| 18 | Trickle-Bed Reactors显示文摘 | C N Satterfield | | 0，，： | 1 |
| 19 | Clinical experience in 82 patients with pancreas divisum:preliminary results of manometry and endoscopic therapy显示文摘 | Satterfield ST McCarthy JH Geenen JE | 1988 | Pancreas1988，3，3： | 1 |
| 20 | Thermodynamic equilibria of selected heterocyclic nitrogen compounds with their hydrogenated derivatives显示文摘 | Cocchetto J F Satterfield C N | | 0，，： | 1 |
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