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8篇 您的检索式：作者名="Saulier"

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		题名	作者	年代	出处	被引量
	1	Comparison between parr and smolt Atlantic salmon (Salmo salar) of subunit gene expression of Na ^+ -K^+ -ATPase in gill tissue 显示文摘	D' COTTA H GMLAIS C SAULIER B	1996	Fish Physiol Biochem1996，15，：	1
	2	Structural lesions in RA:proposition for a new semiquantitative score (ScUSSe:scoring by ultrasound structural erosion)显示文摘	Sommier JP Michel-Batot C Sauliere N	2006	Arthritis Rheum2006，53，：	1
	3	Isolation and partial characterization of feruloylated oilgosaccharides from maize bran显示文摘	Saulier L Vigouroux J Thibault JF	1995	Carbohydr Res1995，272，：	1
	4	Isolation and partial characterization of feruloylated oilgosaccharides from maize bran 显示文摘	Saulier L Vigouroux J Thibault JF	1995	Carbohydr Res1995，272，：	1
	5	Comparing non-enhanced and enhanced sequences in the assessment of effusion and synovitis in knee OA: associations with clinical, macroscopic and microscopic features显示文摘	Loeuille D Sauliere N Champigneulle J	2011	Osteoarthritis Cartilage2011，19，12：	1
	6	Comparing non-enhanced and enhanced sequences in the assessment of effusion and synovitis in knee OA:associations with clinical,macroscopic and microscopic features显示文摘	Loeuille D Sauliere N Champigneulle J		0，，：	1
	7	Structure and function of poly(ADP-ribose) polymerase显示文摘	Gilbert Murcia Valérie Schreiber Miguel Molinete Bénédicte Saulier Olivier Poch Murielle Masson Claude Niedergang Josiane Ménissier Murcia	1994	Molecular and Cellular Biochemistry (-)1994，，1：	1
	8	Physiological and druggable skipping of immunoglobulin variable exons in plasma cells显示文摘The error-prone V(D)J recombination process generates considerable amounts of nonproductive immunoglobulin(Ig)pre-mRNAs.We recently demonstrated that aberrant Ig chains lacking variable(V)domains can be produced after nonsense-associated altered splicing(NAS)events.Remarkably,the expression of these truncated Ig polypeptides heightens endoplasmic reticulum stress and shortens plasma cell(PC)lifespan.Many questions remain regarding the molecular mechanisms underlying this new truncated Ig exclusion(TIE-)checkpoint and its restriction to the ultimate stage of B-cell differentiation.To address these issues,we evaluated the extent of NAS of Ig pre-mRNAs using an Ig heavy chain(IgH)knock-in model that allows for uncoupling of V exon skipping from TIE-induced apoptosis.We found high levels of V exon skipping in PCs compared with B cells,and this skipping was correlated with a biallelic boost in IgH transcription during PC differentiation.Chromatin analysis further revealed that the skipped V exon turned into a pseudo-intron.Finally,we showed that hypertranscription of Ig genes facilitated V exon skipping upon passive administration of splice-switching antisense oligonucleotides(ASOs).Thus,V exon skipping is coupled to transcription and increases as PC differentiation proceeds,likely explaining the late occurrence of the TIE-checkpoint and opening new avenues for ASO-mediated strategies in PC disorders.	Mohamad Omar Ashi Nivine Srour Jean-Marie Lambert Anne Marchalot Ophelie Martin Sandrine Le Noir Eric Pinaud Maria Victoria Ayala Christophe Sirac Jerome Sauliere Jerome Moreaux Michel Cogne Laurent Delpy	2019	Cellular & Molecular Immunology2019，16，10：	0

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