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| 1 | Intestinal epithelial responses to enteric pathogens:effects on the tight junction barrier,ion transport,and inflammation显示文摘 | Berkes J Viswanathan VK Savkovic SD | 2003 | Gut2003，52，3： | 1 |
| 2 | Intestinal epithelial responses to enteric pathogens: ef{ects on the tight junction barrier, ion transport, and in- flammation显示文摘 | Berkes J Viswanathan VK Savkovic SD | 2003 | Gut2003，52，3： | 1 |
| 3 | Intestinal epithelial responses to enteric pathogens:effects on the tight junction barrier,ion transport,and inflammation显示文摘 | Berkes J Viswanathan VK Savkovic SD | | 0，，03： | 1 |
| 4 | Clesterin is protective in pancreatitis through anti-apoptotic and anti-inflammatory properties显示文摘 | Savkovic V Gantzer H Reiser U | | 0，，2： | 1 |
| 5 | In- testinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation显示文摘 | BERKES J VISWANATHANV K SAVKOVIC S D | 2003 | Gut2003，52，3： | 1 |
| 6 | Intestinal microbiome analysis demonstrates azithromycin post-treatment effects improve when combined with lactulose显示文摘Background Next-generation sequencing has revolutionized our perspective on the gut microbiome composition,revealing the true extent of the adverse effects of antibiotics.The impact of antibiotic treatment on gut microbiota must be considered and researched to provide grounds for establishing new treatment strategies that are less devastating on commensal bacteria.This study investigates the impact on gut microbiome when a commonly used antibiotic,azithromycin is administered,as well as uncovers the benefits induced when it is used in combination with lactulose,a prebiotic known to enhance the proliferation of commensal microbes.Methods 16S rRNA gene sequencing analysis of stool samples obtained from 87 children treated with azithromycin in combination with or without lactulose have been determined.Children's gut microbial profile was established at the pre-and post-treatment stage.Results Azithromycin caused an increase in the relative abundance of opportunistic pathogens such as Streptococcus that was evident 60 days after treatment.While few days after treatment,children who also received lactulose started to show a higher relative abundance of saccharolytic bacteria such as Lactobacillus,Enterococcus,Anaerostipes,Blautia and Roseburia,providing a protective role against opportunistic pathogens.In addition,azithromycin-prebiotic combination was able to provide a phylogenetic profile more similar to the pre-treatment stage.Conclusion It is suggested that during azithromycin treatment,lactulose is able to reinstate the microbiome equilibrium much faster as it promotes saccharolytic microbes and provides a homeostatic effect that minimizes the opportunistic pathogen colonization. | Elpiniki Nikolaou Elena Kamilari Dragana Savkov Artemy Sergeev Irina Zakharova Paris Vogazianos Marios Tomazou Athos Antoniades Christos Shammas | 2020 | World Journal of Pediatrics2020，16，2： | 1 |
| 7 | Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation 显示文摘 | BERKES J VISWANATHAN V K SAVKOVIC S D | 2003 | Gut2003，52，3： | 1 |
| 8 | Intestinal epithelial responses to enteric pathogens effects on the tight junction barrier,transport ion and inflammation显示文摘 | Berkes J Viswanathan VK Savkovic SD | 2003 | Gut2003，52，3： | 1 |
| 9 | Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation显示文摘 | Berkes J Viswanathan VK Savkovic SD | 2013 | Gut2013，52，3： | 1 |
| 10 | Activation of NF-kappaB in intestinal epithelial cells by enteropathogenic Escherichia coli显示文摘 | Savkovic SD Koutsouris A Hecht G | 1997 | Am J Physiol1997，273，4： | 1 |
| 11 | Intestinal epithelial re- sponses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation显示文摘 | Berkes J Viswanathan V Savkovic S D | 2003 | Gut2003，52，3： | 1 |
| 12 | Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability 显示文摘 | Yuhan R Koutsouris A Savkovic SD et ai | 1997 | Gastroenterology1997，113，6： | 1 |
| 13 | Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability显示文摘 | YUHAN R KOUTSOURIS A SAVKOVIC S D | 1997 | Gastroenterology1997，113，6： | 1 |
| 14 | Intestinal epithelial responses to enteric pathogens:effects on the tight junction barrier, ion transport,and inflammation 显示文摘 | Berkes J Viswanathan VK Savkovic SD | 2003 | Gut2003，52，3： | 1 |
| 15 | Intestinal epithelial responses to enteric pathogens:effects on the fight junction barrier, ion transport,and inflammation显示文摘 | Berkes J Viswanathan VK Savkovic SD | 2003 | Gut2003，52，3： | 1 |
| 16 | Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation显示文摘 | Berkes J Viswanathan VK Savkovic SD | 2003 | Gut2003，52，： | 1 |
| 17 | Intestinal epithelial responses to enteric pathogens effects on the tight junction barrier,ion transport,and inflammation显示文摘 | Viswanathan VK Savkovic SD | 2003 | Gut2003，52，3： | 1 |
| 18 | Intestinal epithelial responses to enteric pathogens:effects on the tight junction barrier,ion transport,and inflammation显示文摘 | Viswanothan V Savkovic S | 2003 | Gut2003，52，： | 1 |
| 19 | Intestinal epithelial responses to enteric patho- gens:effects on the fight junction barrier, ion trans- port, and inflammation显示文摘 | BERKES J VISWANATHAN V K SAVKOVIC S D | 2003 | Gut2003，52，3： | 1 |
| 20 | Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation 显示文摘 | Berkes J Viswanathan VK Savkovic SD | 2003 | Gut2003，52，3： | 1 |
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