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| 1 | Supplementation of milk formula with galacto-oligosaccharides improves intestinal micro-flora and fermentation in term infants显示文摘Background Oligosaccharides in human milk may protect infants by improving the intestinal micro-flora and fermentation. This study was to investigate effects of infant formula milk consisting of galacto-oligosaccharide (GOS) on intestinal microbial populations and the fermentation characteristics in term infants in comparison with that of human milk. Methods The test formula (Frisolac H,Friesland,Netherland) was supplemented with GOS at a concentration of 0.24 g/dl. Human milk and another formula without oligosaccharides (Frisolac H,Friesland,Netherland) were used as positive and negative control respectively. Growth,stool characteristics,and side effects of the recruited infants were recorded after 3 and 6 months’ follow-up,and the fecal species were collected for the analysis of intestinal micro-flora,short chain fatty acid (SCFA) and pH.Results At the end of 3- and 6-month feeding period,intestinal Bifidobacteria and Lactobacilli were significantly increased in infants fed with GOS supplemented formula and human milk when compared with infants fed with negative control formula; however,there was no statistically significant difference between GOS supplemented formula and human milk groups. Stool characteristics were influenced by the supplement and main fecal SCFA (acetic),and stool frequency were significantly increased in infants fed with GOS supplemented formula and human milk,while the fecal pH was significantly decreased as compared with that of negative control ( P <0.05). Supplementation had no influence on incidence of side effects (including crying,regurgitation and vomiting). Conclusions Supplementing infant formula with GOS at a concentration of 0.24 g/dl stimulates the growth of Bifidobacteria and Lactobacilli in the intestine and stool characteristics are similar to in term infants fed with human milk. | 贲晓明 周晓玉 赵卫华 喻文亮 潘伟 张伟利 吴圣楣 Christien M. Van Beusekom Anne Schaafsma | 2004 | Chinese Medical Journal2004,,6: | 10 |
| 2 | 配方奶添加长链多聚不饱和脂肪酸对足月儿生长发育的影响显示文摘【目的】 拟探讨配方乳添加等量AA与DHA对中国部分地区足月婴儿生长发育的影响。 【方法】 2 71名足月健康新生儿 ,随机分配进入添加AA +DHA配方喂养组 (frisolacadvanced ,FA组 )、未添加AA +DHA配方喂养组 (frisolacH ,FH组 ) ,并选择 2 6名纯母乳喂养儿 (fullybreastfeding ,BF组 )为对照组。所有参与的婴儿在满 3和6个月时邀请入院检测体重、身长、头围、智能发育指数 (MDI) ,运动发育指数 (PDI) ,并采集外周静脉血检测血浆长链多聚不饱和脂肪酸 (LCPUFA)与血红蛋白。 【结果】 尽管两种配方喂养婴儿血清LCPUFA含量差异有显著性 ,但两组配方喂养婴儿在满 3和 6个月时体重、身长、头围、MDI、PDI差异无显著性。然而 ,本研究显示纯母乳喂养婴儿在 6个月时体重和身长低于混合喂养婴儿 (BF组 +FA组 ) ,且BF组婴儿在 6个月时血浆AA、DHA及与血红蛋白低于BF +FA组婴儿。 【结论】 尽管添加AA∶DHA =1∶1的配方可以显著地增加婴儿血浆AA和DHA水平 ,但并不表明对现有的标准婴儿配方乳添加AA +DHA可促进婴儿生长发育。 | 贲晓明 赵卫华 程锐 周晓玉 喻文亮 潘伟 张伟利 吴圣楣 Christien M.VanBeusekom Anne Schaafsma | 2004 | 中国儿童保健杂志2004,12,3: | 3 |
| 3 | Growth and development of term infants fed with milk with long-chain polyunsaturated fatty acid supplementation显示文摘 | 贲晓明 周晓玉 赵卫华 喻文亮 潘伟 张伟利 吴圣楣 Christien M.Van Beusekom Anne Schaafsma | 2004 | Chinese Medical Journal2004,,8: | 3 |
| 4 | Probiotics显示文摘 | F Guarner G.J Schaafsma | 1998 | International Journal of Food Microbiology1998,,3: | 2 |
| 5 | Effects of carob-bean gum thickened formulas on infants' reflux and tolerance indices显示文摘AIM: To examine the effect of carob-bean gum(CBG) thickened-formulas on reflux and tolerance indices in infants with gastro-esophageal reflux(GER). METHODS: Fifty-six eligible infants(1-6 mo old) were randomly allocated to receive for two weeks a formula with either 0.33 g/100 m L(Formula A) or 0.45 g/100 m L(Formula B) of cold soluble CBG galactomannans respectively, or a formula with 0.45 g/100 m L of hot soluble CBG galactomannans(Formula C). No control group receiving standard formula was included in the study. Data on the following indices were obtained both at baseline and follow-up from all study participants: 24 h esophageal p H monitoring indices, anthropometrical indices(i.e., body weight and length) and tolerance indices(i.e., frequency of colics; type and frequency ofdefecations). From the eligible infants, forty seven were included in an intention-to-treat analysis to examine the effects of the two-week trial on esophageal 24 h p H monitoring, growth and tolerance indices. Repeated Measures ANOVA was used to examine the research hypothesis.RESULTS: Regarding changes in 24 h p H monitoring indices, significant decreases from baseline to followup were observed in the 'Boix Ochoa Score'(i.e., an index of esophageal acid exposure), in the total number of visible refluxes and in all symptoms related indices due to acid reflux only for infants provided with Formula A, while no significant changes were observed for infants provided with Formulas B and C. In addition, the significant decreases observed in two symptoms related p H monitoring indices(i.e., 'Symptom index for reflux' and 'Percentage of all reflux') for infants provided with Formula A were also found to differentiate significantly compared to the changes observed in the other two groups(P = 0.048 and P = 0.014 respectively). Concerning changes in anthropometric indices, body weight significantly increased among infants provided with Formulas A and C, but not for infants provided with Formula B. As far as tolerance indices were concerned, the numbers of total and diarrheic defecations increased significantly only in infants provided with Formula B and these changes were significantly higher compared to the decreases observed in infants fed with Formulas A and C(P = 0.003 and P = 0.015 respectively. Lastly the number of colics significantly decreased in all infants, irrespective of the tested formula. CONCLUSION: Formula A(i.e., 0.33 g/100 m L of cold galactomannans) was effective in reducing certain p Hmonitoring indices of uncomplicated GER, increased body weight and was well-tolerated by infants. | Miglena Georgieva Yannis Manios Niya Rasheva Ruzha Pancheva Elena Dimitrova Anne Schaafsma | 2016 | World Journal of Clinical Pediatrics2016,5,1: | 2 |
| 6 | Longterm recurrent subarachnoid hemorrhage after adequate coiling versus clipping of ruptured intracranial aneurysms 显示文摘 | Schaafsma JD Sprengers ME van Rooij W J | 2009 | Strok2009,40,: | 1 |
| 7 | The current and future value of nature-based tourism in the eastern arc mountains of Tanzania显示文摘 | BAYLISS J SCHAAFSMA M BALMFORD A | 2014 | Ecosystem Services2014,8,: | 1 |
| 8 | Fabrication of single-mode chalcogenide optical fiber显示文摘 | Mossadegh R Sanghera J S Schaafsma D | 1998 | Journal of Lightwave Technology1998,16,2: | 1 |
| 9 | Nondigestible oligosaccharides do not interfere with calcium and nonheme-iron absorption in young,healthy men显示文摘 | Heuvel E G Schaafsma G Muys T | 1998 | Am J Clin Nutr1998,67,3: | 1 |
| 10 | Moderate alcohol consumption and platelet aggregation in healthy middleaged men显示文摘 | Van del Pol H Schaafsma G | 1990 | Alcohol1990,7,: | 1 |
| 11 | Three cases of hyperperfusion syn-drome identified by daily transcranial Doppler investigation after ca-rotid surgery显示文摘 | Schaafsma A Veen L Vos JP | 2002 | Ear J Vase Endovase Surg2002,23,1: | 1 |
| 12 | Three cases of hyperperfusion syndrome identified by daily transcranial Doppler investigation after carotid surgery显示文摘 | Schaafsma A Veen L Vos JP | 2002 | Eur J Vasc Endovasc Surg2002,23,1: | 1 |
| 13 | The DONcast model:predicting deoxynivalenol(DON)in wheat显示文摘 | HOOKER D C SCHAAFSMA A W | 2004 | Pathog Epidemiol Dis Forecasting2004,12,2: | 1 |
| 14 | Bladder pressure sensors in an animal model 显示文摘 | Koldewijn EL Van Kerrebroeck PE Schaafsma E | 1994 | J Urol1994,151,5: | 1 |
| 15 | Effect of an EBM Course in Combination with Case Method Learning Sessions: an RCT on Professional Perfor- mance, Job Satisfaction, and Self-effecacy of Occupational Physicians显示文摘 | Hugenhohz N I R Schaafsma F G Nieuwenhuijsen K | 2008 | Int Arch Occup Environ Health2008,82,1: | 1 |
| 16 | Probiotics显示文摘 | Guarmer F Schaafsma GJ | 1998 | International Journal of Food Microbiology1998,39,3: | 1 |
| 17 | Increased numbers of circulating haematopoietic progenitor cells after treatment with highdose interleukin22 cancer patients显示文摘 | Schaafsma MR Fibbe WE Vander HD | 1990 | Br J Haematol1990,76,2: | 1 |
| 18 | Inhalation of the Rhokinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction 显示文摘 | Schaafsma D Bos IS Zuidhof AB | 2006 | Respir Res2006,7,: | 1 |
| 19 | Three cases of hyperperfusion syndrome identified by daily transcranial Doppler investigation after carotid surgery显示文摘 | Schaafsma A Veen L Vos JP | 2002 | Eur J Vasc Endovasc Surg2002,23,1: | 1 |
| 20 | Three cases of hyperperfusion syndrome identified by daily transcranial Doppler investigation after carotid surjery显示文摘 | Schaafsma A Veen L Vos JP | 2002 | Eur J Vase Endovase Surg2002,23,1: | 1 |