维普期刊资源整合服务平台（V6.5）

151篇 您的检索式：作者名="Schultz K M"

选中清除导出查看参考文献查看引证文献引用追踪共8页首页上一页第1页下一页末页 /8 跳转

	题名	作者	年代	出处	被引量
1	星形胶质细胞转录组分析指导的脑卒中靶标鉴定显示文摘星形胶质细胞支持正常的脑功能,但在卒中等病理条件下,星形胶质细胞反应性激活,其也可能参与神经退行性改变。反应性星形胶质细胞增生对机体有益或有害,与环境背景有关,但其分子基础仍未得到充分解释。借助RiboTag技术,我们在特异性地短暂性大脑中动脉闭塞(tMCAO)72h后的小鼠星形胶质细胞中,纯化翻译mRNA,构建卒中特异性星形胶质细胞翻译组数据库。我们发现,与对照组脑组织相比,tMCAO后的反应性星形胶质细胞显示与A2表型相关的转录物的富集,这与神经保护相关。星形胶质细胞也会上调大量潜在的神经毒性基因。我们共鉴定了1003个基因和38个转录因子的差异表达,其中Stat3,Sp1和Spi1变化最明显。为了进一步探索Stat3介导的通路对卒中发病机制的影响,我们选择星形胶质细胞特异性条件性缺失Stat3的小鼠制造tMCAO模型,发现这些小鼠的局灶性缺血卒中体积减少,且梗死72h后小鼠的运动结果改善。综上所述,本研究扩展了新兴的星形胶质细胞特异性靶向卒中治疗数据库,并肯定了星形胶质细胞是脑功能的关键保障细胞。	Rakers C Schleif M Blank N Matu?ková H Ulas T H?ndler K Torres SV Schumacher T Tai K Schultze JL Jackson WS Petzold GC 聂昊	2019	神经损伤与功能重建2019，14，6：	2
2	Biolumines-Cence imaging of vacciniavirus:effects of interfereon on viral replication and spread显示文摘	Luker K Hutchens M Schultz T	2005	Virol2005，341，：	1
3	Demographics and diagnosis of pyridoxinedependent seizures显示文摘	Ebinger M Schultze C K(o)nig S		0，，06：	1
4	The theoretical and numerical determination of the radar cross section of a prolate spheroid显示文摘	Siegel K M Schultz F V	1956	IRE Trans Antennas Propag1956，4，：	1
5	Treatment of cast bronchitis with low-dose oral azithromycin显示文摘	Schultz K D Oerrnarm C M	2003	Pediatr Pulmonol2003，35，2：	1
6	-hydrogenase and models that contain iron-acyl ligation显示文摘	Schultz K M Chen D Hu X	2013	Chem Asian J2013，8，：	1
7	Etiology and incidence of pressure ulcers insurgical patients 显示文摘	Schultz A Bien M Dumond K etal	1999	AORN J1999，70，3：	1
8	Etiology and incidence of pres- sure ulcers in surgical patients显示文摘	Schultz A Bien M Dumond K	1999	Aorn J1999，70，3：	1
9	Expression levels and functional aspects of the hyaluronan receptor CD44 effects of insulin,glucose IGF-I,or growth hormone on human arterial smooth muscle cells显示文摘	SCHULTZ K RASMUSSEN L M LEDET T	2005	Metabol Clin Exp2005，54，3：	1
10	Sediment and nu- trient removal in an established multi species riparian buffer 显示文摘	Lee K H Isenhart T M Schultz R C	2003	Journal of Soil and Water Conservation2003，58，1：	1
11	Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation ininterleukin-10-deficient mice 显示文摘	Sellon R K Tonkonogy S Schultz M	1998	Infect Immun1998，，：	1
12	Resistanceof Chlorpyrifos to Enhanced Biodegradation in Soil显示文摘	RACKE K D LASKOWSKI D A SCHULTZ M R	1990	Journalof Agricultural and Food Chemistry1990，38，6：	1
13	Toward the improvement of aircraft-icing forecasts for the continental United States显示文摘	SCHULTZ P POLITOVICH M K	1992	Weather and Forecasting1992，7，：	1
14	Simvastatin inhibits growth factor expression and modulates profibrogenic markers in lung fibroblasts显示文摘	WATTS K L SAMPSON E M SCHULTZ G S	2005	Am J Respir Cell Mol Biol2005，32，4：	1
15	Pterygia Pathogenesis:Corneal Invasion by Matrix Metalloproteinase Expressioning Altered Limbal Epithelial Basal Cells显示文摘	Dushku N John M K Schultz G S	2002	Arch Ophthalmol2002，120，2：	1
16	Etiology and incidence of pressure ulcers insurgical patients 显示文摘	Schultz A Bien M Dumond K	1999	AORN J1999，70，3：	1
17	Innovativeflowschemes using dividing wall columns显示文摘	SCHULTZ M A BRIEN D E O HOEHN R K	2006	Computer AidedChemical Engineering2006，21，：	1
18	Single-stage antero-posterior decompression and stabilization for complex cervical spine disorder显示文摘	Schultz K D Mclaughlin M R Haid R W	2000	J Neurosurg2000，93，2：	1
19	Etiology and incidence of pres-sure ulcers in surgical patients显示文摘	Schultz A Bien M Dumond K	1999	AORN J1999，70，3：	1
20	Development of windows based on highly insulating aerogei glazings显示文摘	Jensen K I Schultz J M Kristiansen F H	2004	J Non-Cryst Solids2004，，3：	1

返回顶部每页显示：

共8页首页上一页第1页下一页末页 /8 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示