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| 1 | Regulation of the G1 phase of the mammalian cell cycle显示文摘In any multi-cellular organism, the balance between cell division and cell death maintains a constant cell number. Both cell division cycle and cell death are highly regulated events. Whether the cell will proceed through the cycle or not, depends upon whether the conditions required at the checkpoints during the cycle are fulfilled. In higher eucaryotic cells, such as mammalian cells, signals that arrest the cycle usually act at a G1 checkpoint. Cells that pass this restriction point are committed to complete the cycle. Regulation of the GI phase of the cell cycle is extremely complex and involves many different families of proteins such as retinoblastoma family cyclin dependent kinases, cyclins, and cyclic kinase inhibitors. | DONJERKOVIC DUBRRAVKA DAVID W SCOTT (Department of Immunology, Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD) | 2000 | Cell Research2000，10，1： | 18 |
| 2 | Biochar and its importance on nutrient dynamics in soil and plant显示文摘Biochar,an environmentally friendly soil conditioner,is produced using several thermochemical processes.It has unique characteristics like high surface area,porosity,and surface charges.This paper reviews the fertilizer value of biochar,and its effects on soil properties,and nutrient use efficiency of crops.Biochar serves as an important source of plant nutrients,especially nitrogen in biochar produced from manures and wastes at low temperature(≤400℃).The phosphorus,potassium,and other nutrient contents are higher in manure/waste biochars than those in crop residues and woody biochars.The nutrient contents and pH of biochar are positively correlated with pyrolysis temperature,except for nitrogen content.Biochar improves the nutrient retention capacity of soil,which depends on porosity and surface charge of biochar.Biochar increases nitrogen retention in soil by reducing leaching and gaseous loss,and also increases phosphorus availability by decreasing the leaching process in soil.However,for potassium and other nutrients,biochar shows inconsistent(positive and negative)impacts on soil.After addition of biochar,porosity,aggregate stability,and amount of water held in soil increase and bulk density decreases.Mostly,biochar increases soil pH and,thus,influences nutrient availability for plants.Biochar also alters soil biological properties by increasing microbial populations,enzyme activity,soil respiration,and microbial biomass.Finally,nutrient use efficiency and nutrient uptake improve with the application of biochar to soil.Thus,biochar can be a potential nutrient reservoir for plants and a good amendment to improve soil properties. | Md Zahangir Hossain Md Mezbaul Bahar Binoy Sarkar Scott Wilfred Donne Young Sik Ok Kumuduni Niroshika Palansooriya Mary Beth Kirkham Saikat Chowdhury Nanthi Bolan | 2020 | Biochar2020，2，4： | 15 |
| 3 | Activation-induced cell death in B lymphocytes显示文摘Upon encountering the antigen (Ag), the immune system can either develop a specific immune response or enter a specific state of unresponsiveness, tolerance. The response of B cells to their specific Ag can be activation and proliferation, leading to the immune response, or anergy and activation-induced cell death (AICD), leading to tolerance. AICD in B lymphocytes is a highly regulated event initiated by crosslinking of the B cell receptor (BCR). BCR engagement initiates several signaling events such as activation of PLCr, Ras, and PI3K, which generally speaking, lead to survival. However, in the absence of survival signals (CD40 or IL-4R engagement), BCR crosslinking can also promote apoptotic signal transduction pathways such as activation of effector caspases, expression of pro-apoptotic genes, and inhibition of pro-survival genes. The complex interplay between survival and death signals determines the B cell fate and, consequently, the immune response. | DONJERKOVIC DUBRAVKA, DAVID W SCOTT (Department of Immunology, Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD, 20855. USA) | 2000 | Cell Research2000，10，3： | 6 |
| 4 | Extended Preoperative Chemotherapy Does Not Improve Pathologic Response and Increases Postoperative Liver Insufficiency After Hepatic Resection for Colorectal Liver Metastases显示文摘 | Yoji Kishi MD Daria Zorzi MD Carlo M. Contreras MD Dipen M. Maru MD Scott Kopetz MD Dario Ribero MD Manuela Motta MD Nicoletta Ravarino MD Mauro Risio MD Steven A. Curley MD Eddie K. Abdalla MD Lorenzo Capussotti MD Jean-Nicolas Vauthey MD | 2010 | Annals of Surgical Oncology2010，，11： | 3 |
| 5 | Intragastric distribution and gastric emptying of solids and liquids in functional dyspepsia显示文摘 | A. M. Scott FRACP Dr. J. E. Kellow MD FRACP B. Shuter MSc H. Cowan RN A.-M. Corbett NMT J. W. Riley MD FRACP M. R. Lunzer FRCP FRACP R. P. Eckstein FRCPA R. H?schl MD S.-K. Lam MD FRCP FRACP M. P. Jones PhD | 1993 | Digestive Diseases and Sciences1993，，12： | 2 |
| 6 | Aggressive Surgical Management of Peritoneal Carcinomatosis With Low Mortality in a High-Volume Tertiary Cancer Center显示文摘 | Niraj J. Gusani MD Sung W. Cho MD Christos Colovos MD PhD Songwon Seo MS Jan Franko MD PhD Scott D. Richard MD Robert P. Edwards MD Charles K. Brown MD PhD Matthew P. Holtzman MD Herbert J. Zeh MD David L. Bartlett MD | 2008 | Annals of Surgical Oncology2008，，3： | 2 |
| 7 | Thrombocytes respond to lipoolysaccharidethrough Toll - like receptor - 4, and MAP kinase and NF - kappaBpathways leading to expression of interleukin - 6 and cyclooxygen-ase - 2 with production of prostaglandin E2 显示文摘 | Scott T Owens MD | 2008 | Mol Immunol2008，45，4： | 1 |
| 8 | Alpha-and betahaemoglobin chain induced changes in normal erythrocyte deformability:comparison to beta thalassaemia intermedia and Hb H disease显示文摘 | Scott MD Rouyer-Fessard P Ba MS | 1992 | Br J Haematol1992，80，4： | 1 |
| 9 | Mycobacteria other than My- cobaeterium tuberculosis are not present in erythema in duratum/nodu- lar Vaseulitis: A case series and liyerature review of the clinical and histologie findings 显示文摘 | Bayer Gamer IB Cox MD Scott MA | 2005 | J cutaneous patho12005，32，3： | 1 |
| 10 | Computerized axial tomo graphy o f intracerebral and intraventricular hemorrnage显示文摘 | Paul FJ, | 1974 | Radiology1974，112，： | 1 |
| 11 | Toll-like re- ceptor 1 polymorphisms increase susceptibility to can- didemia显示文摘 | Plantinga TS Johnson MD Scott WK | 2012 | J Infect Dis2012，205，6： | 1 |
| 12 | Effect of Candesartan on Cause-Specific Mortality in Heart Failure Patients The Candesartan in Heart failure Assessment of Reduction in Mortality and Morbidity (CHARM) Program显示文摘 | Scott D Solomon MD Duolao Wang phD | 2004 | Circulation2004，110，： | 1 |
| 13 | NADPH,notglutathione,status modulates oxidant sensitivity in normal and glucose phosphate dehydrogenase deficient显示文摘 | Scott MD Zuol Lubin BH | 1991 | Bood1991，77，9： | 1 |
| 14 | H202 injury in beta thalassemic erythrocytes: protective role of catalase and the prooxidant effects of GSH显示文摘 | Scott MD | 2006 | Free Radic Biol Meal2006，40，7： | 1 |
| 15 | Food allergy显示文摘 | Scott H Sicherer MD Hugh A Sampson | 2010 | Journal of Allergy and Clinical Immunology2010，125，2： | 1 |
| 16 | Effect of disc degeneration on lumbar segmental mobility analyzed by kinetic magnetic resonance imaging显示文摘 | Lao L Daubs MD Scott TP | 2015 | Spine (Phila Pa 1976)2015，40，5： | 1 |
| 17 | Marginal mandibular nerve injury during neck dissection and its impact on patient perception of appearance 显示文摘 | Batstone MD Scott B Lowe D | 2009 | Head Neck2009，31，5： | 1 |
| 18 | Beyond the red cell: pegylation of other blood cells and tissues 显示文摘 | Scott MD Chen AM | 2004 | Transfus Clin Biol2004，11，1： | 1 |
| 19 | H202 injury in beta thalassemic erythro- cytes:protective role of catalase and the prooxidant effects of GSH 显示文摘 | Scott MD | 2006 | Free Radic Biol Med2006，40，7： | 1 |
| 20 | Immunocamouflage: prevention of transfusion-induced graft-versus-host disease via polymer grafting of donor cells 显示文摘 | Chen AM Scott MD | 2003 | J Biomed Mater Res A2003，67，2： | 1 |
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