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| 1 | Outcome in obscure gastrointestinal bleeding after capsule endoscopy显示文摘AIM: To investigate the clinical impact of capsule endoscopy(CE) after an obscure gastrointestinal bleeding(OGIB) episode, focusing on diagnostic work-up, followup and predictive factors of rebleeding. METHODS: Patients who were referred to Hospital del Mar(Barcelona, Spain) between 2007 and 2009 for OGIB who underwent a CE were retrospectively analyzed. Demographic data, current treatment with non-steroid antiinflammtory drugs or anticoagulant drugs, hemoglobin levels, transfusion requirements, previous diagnostic tests for the bleeding episode, as well as CE findings(significant or non-significant), work-up and patient out-comes were analyzed from electronic charts. Variables were compared by χ 2 analysis and Student t test. Risk factors of rebleeding were assessed by Log-rank test, Kaplan-Meier curves and Cox regression model. RESULTS: There were 105 patients [45.7% women, median age of 72 years old(interquartile range 56-79)] and a median follow-up of 326 d(interquartile range 123-641) included in this study. The overall diagnostic yield of CE was 58.1%(55.2% and 63.2%, for patients with occult OGIB and overt OGIB, respectively). In 73 patients(69.5%), OGIB was resolved. Multivariate analysis showed that hemoglobin levels lower than 8 g/dL at diagnosis [hazard ratios(HR) = 2.7, 95%CI: 1.9-6.3], patients aged 70 years and above(HR = 2.1, 95%CI: 1.2-6.1) and significant findings in CE(HR = 2.4, 95%CI: 1.1-5.8) were independent predictors of rebleeding. CONCLUSION: One third of the patients presented with rebleeding after CE; risk factors were hemoglobin levels < 8 g/dL, age ≥ 70 years or the presence of significant lesions. | Alex Caas-Ventura Lucia Márque Xavier Bessa Josep Maria DedeuDepartment of Gastroenterology Hospital del Mar Research Institute Pompeu Fabra University Marc Puigvehí Sílvia Delgado-Aros Ines Ana Ibáez Agustin Seoane Luis Barranco Felipe Bory Montserrat Andreu Begoa González-Suárez | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，11： | 4 |
| 2 | A possible role ofneuropeptide Y,agouti-related protein and leptin receptor iso-forms in hypothalamic programming by perinatal feeding in therat显示文摘 | LOPEZ M SEOANE L M TOVAK S | 2005 | Diabetologia2005，48，1： | 1 |
| 3 | Involvement of hidden allergens in food allergic reactions显示文摘 | Anibarro B Seoane F J Mugica M V | 2007 | J Investig Allergol Clin Immonol2007，17，3： | 1 |
| 4 | Limitations of soil enzymes as indicators of soil pollution显示文摘 | Trasar-Cepeda C Lefos M C Seoane S | 2000 | Soil Biology & Biochemistry2000，，32： | 1 |
| 5 | Treatment with fixed thyroxine doses in pregnant women with subclinical hypothyroidism显示文摘 | Seoane Cruz I Penin alvarez M Luna Cano R | 2012 | Endocfinol Nutr2012，59，5： | 1 |
| 6 | Utilization of grass silage by growing cattle:effect of a supplement containing ruminally protected amino acids 显示文摘 | VEIRA D M SEOANE J R PROULX J G | 1991 | Joumai of Animal Science1991，69，12： | 1 |
| 7 | Dependence of mineralization of soil organic matter on temperature and moisture显示文摘 | Leiros M C Trasar-Cepeda C Seoane S | 1999 | Soil Biology and Biochemistry1999，31，： | 1 |
| 8 | A possible role of neuropeptide Y, agouti-related protein and leptin receptor isoforms in hypothalamic programming by perinatal feeding in the rat 显示文摘 | Lopez M Seoane LM Tovar S | 2005 | Diabetologia2005，48，1： | 1 |
| 9 | Influence of endoge- nous leptin tone on the estrous cycle and luteinizing hormone pulsa- tility in female rats 显示文摘 | CARRO E PINILLA L SEOANE L M | 1997 | Neuroendocrinology1997，66，6： | 1 |
| 10 | Crossed aphasia after right anterior temporal lobectomy. A case report显示文摘 | C.P. Múnera C. Lomlomdjian P. Solis N. Medel E. Seoane S. Kochen | 2012 | Epilepsy and Behavior2012，，1： | 1 |
| 11 | Symme- try-breaking analysis for the genellal Helmholtz-Duff- ing oscillator显示文摘 | Cao Hongjun Seoane J M Sanjuan M A F | 2007 | Chaos Solitons & Fractals2007，34，2： | 1 |
| 12 | Hydrode- chlorination of carbon tetrachloride in the liquid phase on a Pd/carbon catalyst: kinetic and mechanistic studies显示文摘 | LUISA M A GOMEZ S L SEOANE A A | 2004 | Appl Catal B: Environ2004，53，2： | 1 |
| 13 | Leptin regulation of prepro-orexin and orexin receptor mRNA levels in the hypothalamus显示文摘 | Lopez M Seoane L Garcla M C | 2000 | Biochem Biophys Res Commun2000，269，1： | 1 |
| 14 | Performance of beef steers fed grass silage with or without supplements of soybean meal, fish meal and barley显示文摘 | Veira D M Proulx J G Seoane J R | 1990 | Can J Anita Sci1990，70，1： | 1 |
| 15 | Dependence of mineralization of soil organic matter on temperature and moisture 显示文摘 | Leirs M C Trasar-Cepeda C Seoane S | 1999 | Soil Biology and Biochemistry1999，31，32： | 1 |
| 16 | Limitations of soil enzymes as indicators of soil pollution 显示文摘 | Trasar-cepeda C Leiros M C Seoane S | 2000 | Soil Biology & Biochemistry2000，，32： | 1 |
| 17 | Dependence of mineralization of soil organic matter on temperature and moisture显示文摘 | Trasar-Cepeda C Seoane S | 1999 | Soil Biology & Biochemistry1999，31，： | 1 |
| 18 | Dependence of mineralization of SOM on temperature and soil moisture 显示文摘 | LEIROS M C TRASAR-CEPEDA SEOANE | 1999 | Soil Biology and Biochemistry1999，31，3： | 1 |
| 19 | The role of the regulatory protein of glucokinase in the glucose sensory mechanism of the hepatocyte显示文摘 | de la Iglesia N Mukhtar M Seoane J | 2000 | J Biol Chem2000，275，10： | 1 |
| 20 | Dependence of mineralization of soil organic matter on temperature and moisture显示文摘 | Leirós M C Trasar-Cepeda C Seoane S | 1999 | Soil Biology & Biochemistry1999，31，： | 1 |
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