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| 1 | Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar. | Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 6 |
| 2 | Heme oxygenase-1 expression in the left atrial myocardium of patients with chronic atrial fibrillation related to mitral valve disease: its regional relationship with structural remodeling 显示文摘 | DOMENICO C M D SERGIO C M D ROBERTA M B | 2008 | Human Pathology2008，39，： | 1 |
| 3 | A model-based direct power control for three-phase power converters显示文摘 | SERGIO V Juan A S Juan M C | | 0，，04： | 1 |
| 4 | Development and application of a capillary electrophoresis based method for the simultaneous screening of six antibiotics in spiked milk samples显示文摘 | Santos Sergio M Henrique's Marilla Duarte Armando C | 2007 | Talanta2007，71，2： | 1 |
| 5 | The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease显示文摘 | Dorothee C Sergio EB Dennis M | 2001 | Science2001，294，： | 1 |
| 6 | Streamtube model for analysis of vertical axis variable pitch turbine for marine currents energy conversion显示文摘 | Sergio M C Vinicio M | 1999 | Energy Conversion & Management1999，41，： | 1 |
| 7 | 查看详情显示文摘 | Aline R B Emilene M B Celine L Maria G R V Sergio L C F Bernhard W | | 0，，： | 1 |
| 8 | Oxidative stress expression status associated to Helicobacter pylori virulence in gastric diseases显示文摘 | Amanda C A Fernanda M Sergio M | 2007 | Clinical Biochemistry2007，40，： | 1 |
| 9 | Alcohol dehydrogenase activitiesand ethanol tolerance in Anastrepha(Diptera,Tephritidae)fruit-fly species and their hybrids显示文摘 | Eneas C Vera N S Sergio R M | 2009 | Genet Mol Biol2009，32，1： | 1 |
| 10 | Blunted nocturnal fall in blood pressure and left ventricular mass in elderly individuals with re- cently diagnosed isolated systolic hypertension 显示文摘 | Paolo C Sergio M Luigi O | 2003 | Am J Hypertens2003，16，11： | 1 |
| 11 | Map-based cloning of a protein kinase gene conferring disease resistance in tomato 显示文摘 | SERGIO H B JULAPARK C | 1993 | Science1993，262，26： | 1 |
| 12 | Structure and population dynamics of Pinus lagunae M F Passini显示文摘 | Sarad Carmen M Sergio A C | 2000 | Forest Ecology and Management2000，13，： | 1 |
| 13 | Impact of diabetes and hy- pertension on left ventricular longitudinal systolic function显示文摘 | Piercarlo B Matteo C Sergio M | 2010 | Di- abetes Research and Clinical Practice2010，90，9： | 1 |
| 14 | 显示文摘 | Jorge M V Claudio F R Sergio C | 2007 | Material Characterization2007，58，： | 1 |
| 15 | Design of a Boost power factor correction converter using optimization techniques 显示文摘 | SERGIO B M CRABBIER J C SCOTT R | 2004 | IEEE Trans on Power Electronics2004，19，6： | 1 |
| 16 | The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease 显示文摘 | DOROTHEE C SERGIO EB DENNIS M | 2001 | Science2001，294，： | 1 |
| 17 | Use of factorial design for optimizationof microwave-assisted digestion of lubricating oil显示文摘 | LETICIA M COSTA SERGIO L C FERREIRA ANARITA A Nogueira | 2005 | BrazChem Soc2005，16，6： | 1 |
| 18 | Toxicity prevention with amifostine in pediatric osteosareoma patients treated with cisplatin and doxorubiein 显示文摘 | SERGIO G C ARMANDO M A ALEJANDRO M B | 2007 | Pediat Hematol Oncol2007，24，6： | 1 |
| 19 | Partial characterization of exopolysaccharides exudated by planktonic diatoms maintained in batch cultures显示文摘 | Sergio M L Maria C G Ivorme D | 2003 | Acta Oecologica2003，，24： | 1 |
| 20 | Reliable low-density DNA array based on allele-specific probes for detection of 118 mutations causing familial hypercholesterolemia 显示文摘 | Diego T Sergio C Pilaf M | 2005 | Clin Chem2005，51，7： | 1 |
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