|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Deep carbon cycles constrained by a large-scale mantle Mg isotope anomaly in eastern China显示文摘Although deep carbon recycling plays an important role in the atmospheric CO_2 budget and climate changes through geological time,the precise mechanisms remain poorly understood.Since recycled sedimentary carbonate through plate subduction is the main light-δ^(26)Mg reservoir within deep-Earth,Mg isotope variation in mantle-derived melts provides a novel perspective when investigating deep carbon cycling.Here,we show that the Late Cretaceous and Cenozoic continental basalts from 13 regions covering the whole of eastern China have low δ^(26)Mg isotopic compositions,while the Early Cretaceous basalts from the same area and the island arc basalts from circum-Paciic subduction zones have mantle-like or heavy Mg isotopic characteristics.hus,a large-scale mantle low δ^(26)Mg anomaly in eastern China has been delineated,suggesting the contribution of sedimentary carbonates recycled into the upper mantle,but limited into the lower mantle.his large-scale spatial and temporal variation of Mg isotopes in the mantle places severe constraints on deep carbon recycling via oceanic subduction. | Shu-Guang Li Wei Yang Shah Ke Xunan Meng Hengci Tian Lijuan Xu Yongsheng He Jian Huang Xuan-Ce Wang Qunke Xia Weidong Sun Xiaoyong Yang Zhong-Yuan Ren Haiquan Wei Yongsheng Liu Fancong Meng Jun Yan | 2017 | National Science Review2017，4，1： | 23 |
| 2 | Object-based classification approach for greenhouse mapping using Landsat-8 imagery显示文摘Suburban greenhouses with intensive agricultural productivity have increasingly influenced the daily diet and vegetable supply in Chinese cities.With their enormous input of fertilizers and pesticides,greenhouses have considerably changed the local soil quality and environmental risk factors.The ability to obtain timely and accurate information regarding the spatial distribution of greenhouses could make an important contribution to local agricultural management and soil protection.This paper attempts to present a practical framework for extracting suburban greenhouses,integrating remote sensing data from Landsat-8 and object-oriented classification.Inheritance classification was implemented,and various properties,including texture and neighborhood features in addition to spectral information,were investigated through the popular random forest technique for feature selection prior to SVM classification to improve the mapping accuracy.The results demonstrated that object-based classification incorporating non-spectral features yielded a significant improvement compared with the classification results obtained using only the spectral information in traditional per-pixel classification.Both the producer’s and user’s accuracy were higher than 85%for greenhouse identification.Although it remained a challenge to completely distinguish greenhouses from sparse plants,the final greenhouse map indicated that the proposed object-based classification scheme,providing multiple feature selections and multi-scale analysis,yielded worthwhile information when applied to a continuous series of the freely available Landsat-8 imagery data. | Wu Chaofan Deng Jinsong Wang Ke Ma Ligang Amir Reza Shah Tahmassebi | 2016 | International Journal of Agricultural and Biological Engineering2016，9，1： | 7 |
| 3 | NDVI-Based Lacunarity Texture for Improving Identification of Torreya Using Object-Oriented Method显示文摘Normalized Difference Vegetation Index(NDVI) is a very useful feature for differentiating vegetation and non-vegetation in remote sensed imagery.In the light of the function of NDVI and the spatial patterns of the vegetation landscapes,we proposed the lacunarity texture derived from NDVI to characterize the spatial patterns of vegetation landscapes concerning the 'gappiness' or 'emptiness' characteristics.The NDVI-based lacunarity texture was incorporated into object-oriented classification for improving the identification of vegetation categories,especially Torreya which was the targeted tree species in the present research.A three-level hierarchical network of image objects was defined and the proposed texture was integrated as potential sources of information in the rules base.A knowledge base of rules created by classifier C5.0 indicated that the texture could potentially be applied in object-oriented classification.It was found that the addition of such texture improved the identification of every vegetation category.The results demonstrated that the texture could characterize the spatial patterns of vegetation structures,which could be a promising approach for vegetation identification. | HAN Ning WU Jing Amir Reza Shah Tahmassebi XU Hong-wei WANG Ke | 2011 | Agricultural Sciences in China2011，10，9： | 5 |
| 4 | Enhancement of Cd Solubility and Bioavailability Induced by Straw Incorporation in Cd-Polluted Rice Soil显示文摘 | Yuhua Shah Haitao Zhao Xiaozhi Wang Ke Feng | 2012 | Journal of Environmental Science and Engineering(A)2012，1，4： | 2 |
| 5 | Structural Comparison and Drug Screening of Spike Proteins of Ten SARS-CoV-2 Variants显示文摘SARS-CoV-2(severe acute respiratory syndrome coronavirus 2)has evolved many variants with stronger infectivity and immune evasion than the original strain,including Alpha,Beta,Gamma,Delta,Epsilon,Kappa,lota,Lambda,and 21H strains.Amino acid mutations are enriched in the spike protein of SARS CoV-2.which plays a crucial role in cell infetion.However,the impact of these mutations on protein structure and function is unclear.Understanding the pathophysiology and pandemic feaures of these SARS-CoV-2 variants requires knowledge of the spike protein structures.Here,we obtained the spike protein structures of 10 main globally endemic SARS CoV-2 strains using AlphaFold2.The clustering analysis based on structural similarity revealed the unique features of the mainly pandemic SARS CoV-2 Delta variants.indicating that structural clusters can reflect the current characteristics of the epidemic more accurately than those based on the protein sequence.The analysis of the binding afinities of ACE2-RBD,antibody-NTD,and antibody-RBD complexes in the different variants revealed that the recognition of antibodies against SI NTD and RBD was decreased in the variants,especally the Delta variant compared with the original strain,which may induce the immune evasion of SARS-CoV-2 variants.Furthermore,by virtual screening the ZINC database against a high-accuracy predicted structure of Delta spike protein and experimental validation,we identified multiple compounds that target S1 NTD and RBD,which might contribute towards the development of clinical anti-SARS-CoV-2 medicines.Our findings provided a basic foundation for future in vitro and in vivo investigations that might speed up the development of potential therapies for the SARS-CoV-2 va riants. | Qiangzhen Yang Xuemin Jian Ali Alamdar Shah Syed Aamir Fahira Chenxiang Zheng zijia Zhu Ke Wang Jinmai Zhang Yangin Wen Zhiqiang Li Dun Pan Tingting Lu Zhuo Wang Yongyong Shi | 2022 | Research2022，，2： | 2 |
| 6 | Synthesis of surface imprinted polymers based on wrinkled flower-like magnetic graphene microspheres with favorable recognition ability for BSA显示文摘Nowadays,the employing of molecular imprinting technique in the analysis and separation of proteins from complex biological samples has been widely favored by researchers.To enrich the types of surface protein imprinted materials and expand the application fields of graphene materials,novel surface molecular imprinted polymers(MIPs)based on magnetic graphene microspheres Fe_(3)O_(4)@r GO@MIPs are first synthesized in this paper.Fe_(3)O_(4)@r GO@MIPs are prepared by oxidative self-polymerization of dopamine on the surface of magnetic graphene(Fe_(3)O_(4)@r GO)composite microspheres.Bovine serum albumin(BSA)is selected as protein template.Fe_(3)O_(4)@r GO microspheres with wrinkled flower-like structure are obtained by compounding Fe_(3)O_(4)and graphene oxide in an appropriate ratio via the method of high-temperature reduction self-assembly.The microspheres exhibit promising dispersibility,high external surface area,rich pore structure,and sufficient magnetic properties.These advantages not only prevent the agglomeration of imprinted microspheres in the aqueous phase,which is conducive to contact and static adsorption,but also increase the amount of protein imprinting.Additionally,sufficient magnetic properties ensure fast and effective separation of the adsorbents.While the adsorption capacity is increased,the separation procedure becomes simple.The binding capacity of Fe_(3)O_(4)@r GO@MIPs for BSA can reach 317.58 mg/g within 60 min,and the imprinting factor(IF)is 4.24.More importantly,Fe_(3)O_(4)@r GO@MIPs can specifically recognize the target BSA from the mixed proteins and the actual sample.There is no significant decrease in the adsorption amount,IF,and magnetic properties after eight runs.It is promising to be used in the separation of proteins from the actual biological samples. | Zuoting Yang Ke Yang Yuhong Cui Tariq Shah Mudasir Ahmad Qiuyu Zhang Baoliang Zhang | 2021 | Journal of Materials Science & Technology2021，，15： | 2 |
| 7 | Advanced gastric cancer-slow but steady progTess显示文摘 | Power DG Ke|sen DP Shah MA | 2010 | Cancer Treat Rev2010，56，5： | 1 |
| 8 | Manganese superoxide dis- mutase protects mouse cortical neurons from chronic inter- mittent hypoxia-mediated oxidative damage显示文摘 | Shah X Chi L Ke Y | 2007 | Neurobiol Dis2007，28，2： | 1 |
| 9 | Different responses of insulin,C-peptide, and testosterone to an oral glucose tolerance test in two groups of women with polycystic ovarian syndrome 显示文摘 | Ke WX Shah GQ Hua SY | 1996 | Acta Obstet Gynecol Scand1996，75，2： | 1 |
| 10 | Nitrate application affects root morphology by altering hormonal status and gene expression patterns in B9 apple rootstock nursery plants显示文摘Lateral roots(LRs)are critical for absorbing water,minerals,and nutrients.Nitrate is a vital signaling molecule for regulating LR growth.However,understanding how nitrate interacts with endogenous hormones and genes to coordinate LR development is a bottleneck.In this study,B9 apple rootstock nursery plants were cultured hydroponically and treated with different nitrate treatments(Control;T1,2.25 mM L^(−1);T2,9 mM L^(−1);T3,18 mM L^(−1);T4,36 mM L^(−1);and T5,72 mM L^(−1)),where T5 outperformed the other treatments.Nursery plants were subsequently treated with control and T5 to explore the underlying physiological and molecular mechanisms by which nitrate promoted LR growth.Plant height,stem diameter,root morphological parameters,endogenous hormones,and gene expression levels were measured.Results showed that T5 promoted LR growth by increasing the endogenous contents of indole-3-acetic acid(IAA)and gibberellic acid(GA),and by decreasing the contents of abscisic acid(ABA),jasmonic acid(JA),and zeatin riboside(ZR)at most time points.Furthermore,the relative expression levels of nitrate transporter genes were upregulated in the control group,and nitrate assimilation genes were upregulated in T5 nursery plants at various time points.In addition,the transcript abundances of auxin-related genes were higher in T5 nursery plants,which increased auxin contents.MdSHR,MdGATA1,and MdSCR1 expressions were induced,hence increasing LR growth.In contrast,higher auxin content raised MdWOX11 expression,which enhanced the MdLBD16 and MdLBD29 expression levels,thus prompting the transcripts of cell cycle-related genes:MdCYCD1;1 and MdCYCP4;1.Overall,the changes in hormonal content and gene expression levels followed superior LR growth by T5. | Muhammad Mobeen Tahir Xiaoyun Zhang Kamran Shah Faisal Hayat Shaohuan Li Jiangping Mao ke Li Yu Liu Yun Shao Dong Zhang | 2021 | Fruit Research2021，1，1： | 1 |
| 11 | Novel transcatheter closure of an iatrogenic perimembranous ventricular septal defect显示文摘 | Retzer EM Dill KE Shah AP | 2015 | Catheter Cardiovasc Interv2015，85，： | 1 |
| 12 | The effect of angio- tensin-blocking agents on liver fibrosis in patients with hepatitis C显示文摘 | Corey KE Shah N Misdraji J | 2009 | Liver Int2009，29，5： | 1 |
| 13 | Androgen excess contrib, utes to altered growth hormone/insulin-like growth factor - 1 axis in nonobese women with policystic ovary syndrome显示文摘 | Kirsimarja Sallinen Xiao - ke Wu Shah - ying Zhou | 2000 | Fertility and Sterility2000，73，4： | 1 |
| 14 | A child with Erysipelothrix-beware of the little known显示文摘Erysipelothrix rhusiopathiaeis an established animal pathogen while the zoonotic infections in humans are rarely reported. Infections occur after exposure to animals or animal products that are mostly occupational in adults. Here we report in a child for the first time septic arthritis and osteomyelitis without an identifiable risk factor. A 5-year-old male child was admitted with pain in the left hip joint and inability to bear weight on the limb. Clinical examination followed by radiological and magnetic resonance imaging was suggestive of septic arthritis.Erysipelothrix rhusiopathiaegrew from peroperative joint specimen. The infection was resolved following arthrotomy, joint lavage and antibiotic therapy. | Chiranjay Mukhopadhyay Hitesh Shah KE Vandana Frenil Munim Sandeep Vijayan | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，6： | 1 |
| 15 | The effects of thermo-mechanical control process on microstructure and mechanical properties of a commercial pipeline stee 显示文摘 | Ming-Chun Zhao Ke YarN Yi-Ying Shah | 2002 | Materials Science and Engineering2002，335，： | 1 |
| 16 | Immunity-and-matrix-regulatory cells enhance cartilage regeneration for meniscus injuries: a phase I dose-escalation trial显示文摘Immunity-and-matrix-regulatory cells(IMRCs)derived from human embryonic stem cells have unique abilities in modulating immunity and regulating the extracellular matrix,which could be mass-produced with stable biological properties.Despite resemblance to mesenchymal stem cells(MSCs)in terms of self-renew and tri-lineage differentiation,the ability of IMRCs to repair the meniscus and the underlying mechanism remains undetermined.Here,we showed that IMRCs demonstrated stronger immunomodulatory and pro-regenerative potential than umbilical cord MSCs when stimulated by synovial fluid from patients with meniscus injury.Following injection into the knees of rabbits with meniscal injury,IMRCs enhanced endogenous fibrocartilage regeneration.In the dose-escalating phase I clinical trial(NCT03839238)with eighteen patients recruited,we found that intra-articular IMRCs injection in patients was safe over 12 months post-grafting.Furthermore,the effective results of magnetic resonance imaging(MRI)of meniscus repair and knee functional scores suggested that 5×107 cells are optimal for meniscus injury treatment.In summary,we present the first report of a phase I clinical trial using IMRCs to treat meniscus injury.Our results demonstrated that intra-articular injection of IMRCs is a safe and effective therapy by providing a permissive niche for cartilage regeneration. | Liangjiang Huang Song Zhang Jun Wu Baojie Guo Tingting Gao Sayed Zulfiqar Ali Shah Bo Huang Yajie Li Bo Zhu Jiaqi Fan Liu Wang Yani Xiao Wenjing Liu Yao Tian Zhengyu Fang Yingying Lv Lingfeng Xie Sheng Yao Gaotan Ke Xiaolin Huang Ying Huang Yujuan Li Yi Jia Zhongwen Li Guihai Feng Yan Huo Wei Li Qi Zhou Jie Hao Baoyang Hu Hong Chen | 2023 | Signal Transduction and Targeted Therapy2023，8，12： | 0 |
| 17 | 体内选择性内皮细胞胰岛素敏感性增强:一种新的促使动脉粥样硬化的信号通路显示文摘在内皮中,胰岛素刺激内皮型一氧化氮合酶(endothelial nitric oxide synthase,eNOS)以产生抗动脉粥样硬化信号的自由基——一氧化氮。2型糖尿病患者可利用的一氧化氮减少,导致动脉粥样硬化改变。内皮细胞胰岛素敏感性增加对一氧化氮合成的影响尚不清楚。为了回答这个问题,该研究使用Tie2启动子增强子构建内皮细胞特异性过表达人类胰岛素受体(endothelial cell-specific over-expression of the human insulin receptor, hlRECO)的小鼠模型。 | 刘莉 叶鹏 Viswambharan H Yuldasheva NY Sengupta A Imrie H Gage MC Haywood NJ Walker AM Skromna A Makova N Galloway SL Shah P Sukumar P Porter KE Grant PJ Shah AM Santos CX Li J Beech DJ Wheatcroft S Cubbon RM Kearney MT | 2016 | 中华高血压杂志2016，24，12： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员