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| 1 | Discovery of potent, selective and orally bioavailable triaryl -sul- fonamide based PTP1B inhibitors 显示文摘 | Dipam Patel Mukul Jain Shailesh R | 2012 | Med Chem Lett2012，22，： | 1 |
| 2 | Cataplasm-based controlled drug delivery: Development and optimization of a novel formulation显示文摘 | Vikas A Shailesh K S Indra K R | 1999 | Drug Dev Ind Pharm1999，25，5： | 1 |
| 3 | Quality of life and oral potentially malignant disorders: Critical appraisal and prospects显示文摘Quality of life(QoL) is a vital and often required health outcome measure that is relevant to patient care. A healthy oral cavity enables person to perform daily activities without any limitations. However, any disturbance may result in impaired QoL. The oral health-remains an essential element of people's health and well-being. In recent years, the tradition of clinical practice and research has been changed by incorporating QoL assessment, as it helps in assessment of patients' needs and monitoring treatment responses. Oral potentially malignant disorders(OPMDs) are a group of chronic disorders including oral leukoplakia(OL), oral lichen planus and oral submucous fibrosis(OSF). It is evident that patients with OPMDs experience significant health-related symptoms, functional limitations and psycho-social impairment, compromising their Qo L. Moreover, the worsening of Qo L has been associated with advanced stages of OPMDs. Despite of increasing number of OPMD cases in recent decades, limited literature is available regarding QoL in this population. Although, there is higher prevalence of habit-related OPMDs, particularly OSF and OL in Southern Asian countries, only a few studies have been performed in these populations. Moreover, these studies administered generic Qo L instruments, which offer less sensitivity to clinical changes. However, condition-specific instruments are more sensitive and allows better measurement of QoL. As the impacts of different conditions on OHRQoL may vary, the development and validation of a QoL instrument specific to each clinical entity of OPMDs is currently needed. | Shailesh M Gondivkar Rahul R Bhowate Amol R Gadbail Sachin C Sarode Shankargouda Patil | 2018 | World Journal of Clinical Oncology2018，9，4： | 1 |
| 4 | Acidic ionic liquid immo-bilized on cellulose ; An efficient and recyclable heterogeneous catalystfor the solventfree synthesis of hydroxylated trisubstituted pyridines显示文摘 | SHAILESH P S’PIYUSH N K DIPAK K R | 2013 | RSC Advances2013，3，： | 1 |
| 5 | On the Trade-offs between Risk Pooling and Logistics Costs in a Multi-plant Network with Commonality显示文摘 | MICHAEL J M AMITABH S R | 2005 | IIE Transactions2005，37，3： | 1 |
| 6 | Group effect on driven piles under lateral load 显示文摘 | Gandhi Shailesh R | 1997 | Journal of Geoteehnical and Geoenvironmental Engi- neering1997，123，8： | 1 |
| 7 | Purification and characterization of an extraeellular antifungal chitinase from Penicilliura ochrochloron MTCC 517 and its application in protoplast formation 显示文摘 | Nilambari S P Shailesh R W Jyoti P J | 2013 | Process Biochemistry2013，48，1： | 1 |
| 8 | Pancreatic Anasto- moses after Pancreaticoduodenectomy: Do We Need Further Studies?显示文摘 | Shailesh VS Sajid SQ Nanda R | 2005 | World J Surg2005，29，： | 1 |
| 9 | A compara- tive study of approaches used to improve solubility of rox- ithromycin显示文摘 | Shailesh V B Arpana R P Guditi V S | 2006 | Powder Technology2006，169，1： | 1 |
| 10 | A comparison of the properties of porous silicon formed on polished and textured (100) Si: High resolution XRD and PL studies 显示文摘 | Bhagavannarayana G Shailesh N S Sharma R K | 2006 | Materials Chemistry and Physics2006，97，： | 1 |
| 11 | A comparative study of approaches used to improve solubility of roxithromycin显示文摘 | Shailesh V B Arpana R P Guditi V S | 2006 | Powder Technology2006，169，1： | 1 |
| 12 | Rescue from complications after pancreaticoduodenectomies at a low-volume Caribbean center:Value of tailored peri-pancreatectomy protocols显示文摘BACKGROUND Pancreaticoduodenectomy(PD)is a technically complex operation,with a re-latively high risk for complications.The ability to rescue patients from post-PD complications is as a recognized quality measure.Tailored protocols were instituted at our low volume facility in the year 2013.AIM To document the rate of rescue from post-PD complications with tailored protocols in place as a measure of quality.METHODS A retrospective audit was performed to collect data from patients who experienced major post-PD complications at a low volume pancreatic surgery unit in Trinidad and Tobago between January 1,2013 and June 30,2023.Stan-dardized definitions from the International Study Group of Pancreatic Surgery were used to define post-PD complications,and the modified Clavien-Dindo classification was used to classify post-PD complications.RESULTS Over the study period,113 patients at a mean age of 57.5 years(standard deviation[SD]±9.23;range:30-90;median:56)underwent PDs at this facility.Major complications were recorded in 33(29.2%)patients at a mean age of 53.8 years(SD:±7.9).Twenty-nine(87.9%)patients who experienced major morbidity were salvaged after aggre-ssive treatment of their complication.Four(3.5%)died from bleeding pseudoaneurysm(1),septic shock secondary to a bile leak(1),anastomotic leak(1),and myocardial infarction(1).There was a significantly greater salvage rate in patients with American Society of Anesthesiologists scores≤2(93.3%vs 25%;P=0.0024).CONCLUSION This paper adds to the growing body of evidence that volume alone should not be used as a marker of quality for patients requiring PD.Despite low volumes at our facility,we demonstrated that 87.9%of patients were rescued from major complications.We attributed this to several factors including development of rescue protocols,the competence of the pancreatic surgery teams and continuous,and adaptive learning by the entire institution,cul-minating in the development of tailored peri-pancreatectomy protocols. | Shamir O Cawich Elijah Dixon Parul J Shukla Shailesh V Shrikhande Rahul R Deshpande Fawwaz Mohammed Neil W Pearce Wesley Francis Shaneeta Johnson Johann Bujhawan | 2024 | World Journal of Gastrointestinal Surgery2024，16，3： | 0 |
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