|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Annexin A2 as a biomarker for hepatocellular carcinoma in Egyptian patients显示文摘AIM To investigate the clinical utility of serum annexin A2(ANXA2) as a diagnostic marker for early hepatocellular carcinoma(HCC).METHODS This study was performed in HCC Clinic of Ain Shams University Hospitals, Cairo, Egypt and included: Group 1: Fifty patients with early stage HCC(Barcelona Clinic Liver Cancer stage A); Group 2: Twenty five patients with chronic liver disease; and Control Group: Fifteen healthy, age-and sex-matched subjects who were seronegative for viral hepatitis markers. The followinglaboratory investigations were done: Viral hepatitis markers [hepatitis B surface antigen and hepatitis C virus(HCV) antibodies], HCV RNA in HCV antibody-positive patients, serum alpha fetoprotein(AFP), and serum ANXA2 levels.RESULTS In this study, 88% of HCC patients(n = 44) were HCVpositive, while HBV infection represented only 8% of all HCC patients(n = 4); and two patients were negative for both viral markers. A highly significant difference was found between patients with HCC and chronic liver disease as well as controls with regard to serum ANXA2 levels(130, IQR 15-240; 15, IQR 15-17; and 17, IQR 15-30 ng/m L, respectively). The area under the curve of ANXA2 was 0.865; the cut-off value was established to be 18 ng/mL with a diagnostic sensitivity of 74% and a specificity of 88%, while the sensitivity and specificity of AFP at the cut-off value of 200 ng/dL were 20% and 100%, respectively.CONCLUSION Serum ANXA2 may serve as a biomarker for the early detection of HCC. | Mohamed K Shaker Hanzada I Abdel Fattah Ghada S Sabbour Iman F Montasser Sara M Abdelhakam Eman El Hadidy Rehab Yousry Ahmed K El Dorry | 2017 | World Journal of Hepatology2017，9，9： | 4 |
| 2 | Application of high-resolution Stereo satellite images to detailed landslide hazard assessment 显示文摘 | Nichl J E Shaker A Wong M S | 2006 | GeogTaphology2006，76，12： | 1 |
| 3 | Momparler,preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza 2-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells显示文摘 | Shaker S Bernstein M Momparler L F | 2003 | Leuk Res2003，27，5： | 1 |
| 4 | Deposition of heavy metals on green leafy vegetable sold on roadside of Riyadh city,Saudi Arabia显示文摘 | M S Jassir A Shaker M A Khaliq | | 0，，： | 1 |
| 5 | Application of high-resolution stereo satellite images to detailed landslide hazard assessment显示文摘 | Nichol J E Shaker A Wong M S | 2006 | Geomorphology2006，76，12： | 1 |
| 6 | The c 2 reactive protein显示文摘 | C lyne B Ol shaker J S | 1999 | JEmerg Med1999，17，6： | 1 |
| 7 | Durability of styrene-butadiene latex modified concrete显示文摘 | Ei-Dieb A S Reda M M | 1997 | Cement and Concrete Research1997，27，4： | 1 |
| 8 | Activation of expression of p15,p73 and E-cadherin in leukemic cells by different concentrations of 5-aza-2'-deoxycytidine (Decitabine)显示文摘 | Farinha NJ Shaker S Lemaire M | 2004 | Anticancer Res2004，24，1： | 1 |
| 9 | Quantitative Analysis of Pulmonary Emphysema Using Local Binary Patterns 显示文摘 | SORENSEN L SHAKER S B de BRUIJNE M | 2010 | IEEE Transactions on Medical Imaging2010，29，2： | 1 |
| 10 | Primary nocturnal en- uresis :a new approach to conditioning treatment 显示文摘 | El - Anany F G Maghraby H A Shaker S E | 1999 | Urology1999，，02： | 1 |
| 11 | Antioxidative effect of extracts from red grape seed and peel on lipid oxidation in oils of sunflower显示文摘 | Shaker E S | 2006 | LWT- Food Sci Technol2006，39，： | 1 |
| 12 | New CMOS fully - differential transconductor and application to a fully differential gm - c filter显示文摘 | SHAKER M O MAHMOUD S A SOLIMAN A M | 2006 | ETRL Journal2006，28，： | 1 |
| 13 | The role of structural chemistry in the inhibitive performance of some aminopyrimidines on the corrosion of steel显示文摘 | MASOUD M S AWAD M K SHAKER M A | 2010 | Corrosion Science2010，52，： | 1 |
| 14 | Defiant dysphagia: small-caliber esophagus and refractory benign esophageal strictures 显示文摘 | Vasilopoulos S Shaker R | 2001 | Curr Gastroenterol Rep2001，3，： | 1 |
| 15 | Detection of myxovirus resistance protein A in lichen planus lesions and its relationship to hepatitis C virus显示文摘 | Shaker OG Hantar N El-Tahlawi S | 2009 | Br J Dermatol2009，160，5： | 1 |
| 16 | Durability of styrene butadiene latex modified concrete 显示文摘 | Shaker F A Ei-Dieb A S Reda M M | 1997 | Cement and Concrete Research1997，27，5： | 1 |
| 17 | Predictors and financial outcomes of corporate entrepreneurship : an exploratory study 显示文摘 | Zahra S A Shaker A | 1991 | Journal of Business Venturing1991，6，4： | 1 |
| 18 | Primary nocturnal enuresis:a new approach to conditioning treatment显示文摘 | Maghraby H A Shaker S E | 1999 | Urology1999，53，2： | 1 |
| 19 | Sacral root neuromodulation: an effective treatment for refractory urge incontinence显示文摘 | Shaker H S Hassotma M | 1998 | J Urol1998，159，5： | 1 |
| 20 | The Early FeedingSkills Assessment for Preterm Fnfants显示文摘 | Thoyre S M Shaker C S Pridham K F | 2005 | Neonatal Netw2005，24，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员