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| 1 | 基于数值仿真的全箭动特性获取技术显示文摘and then in the absence of test data to establish the dynamic model.The issue was,how to accurately obtain the mode data of LM-8 with numerical simulations which directly affects the control reliability of flight.In this paper,various approaches to obtain the dynamic characteristics of LM-8 are described from the perspective of refined dynamic modeling and simulating,mode slope prediction,vertical modal test,etc.The numerical simulations were found to be in good agreement with the experimental data,and satisfied the requirements for the engineering application,which effectively supported the successful maiden flight mission of LM-8. | YANG Shutao YUAN He XU Shanshu WU Yitian SONG Zhengyu | 2021 | Aerospace China2021，22，2： | 2 |
| 2 | Lipoxygenase inhibitors suppressed carrageenan-induced Fos-expression and inflammatory pain responses in the rat显示文摘 | Sungjae Yoo Shanshu Han Young Shin Park Jang-Hern Lee Uhtaek Oh Sun Wook Hwang | 2009 | Molecules and Cells2009，，4： | 1 |
| 3 | Hybrid continuum/DSMC computation of rocket mode lightcraft flow in near space with high temperature and rarefaction effect显示文摘 | Xu Shanshu Wu Ziniu Li Qian | 2009 | Computers and Fluids2009，38，7： | 1 |
| 4 | Protective effect of melatonin on neurons after oxidative-stress injury显示文摘BACKGROUND: It has been suggested that melatonin(MT) can protect secondary neuronal injury.However,the protective effect of MT on neuronal injury in ischemia/reperfusion models in vitro still has not been proved.OBJECTIVE:To investigate the protective effect of MT on central ischemic injury of nerve cells and analyze its possible mechanism.DESIGN: Contrast observational study.SETTING: Department of Biochemistry and Molecular Biology,Tongji Medical College,Huazhong University of Science and Technology.MATERIALS: Rats aged 7-8 days and weighing 10-12g were provided by Medical Experimental Animal Center,Tongji Medical College,Huazhong University of Science and Technology,MT was provided by Sigma Company,USA.METHODS:The experiment was carried out in the Laboratory of Biochemistry and Molecular Biology,Tongji Hospital,Huazhong University of Science and Technology from October 2002 to March 2004.The effects of MT on the neurodegeneration induced by oxygen-glucose-deprivation (OGD) were tested in cultured rat cerebellar granule cells.Neuron damage was quantitatively assessed by Typan Blue exclusion and MTT assay at different time points after oxygen-glucose-deprivation(90 minutes).DNA gel electrophoresis and acridine orange stain were performed to determine the nature of cell damage.And fluorescence spectrophotometer was used for quantification of intracellular malondialdehyde(MDA)at various time intervals.MAIN OUTCOME MEASURES: Correlation between degrees of neuronal injury and reperfusion times,apoptosis,and production of MDA in cells.RESULTS:①The neuron injury was aggravated with reperfusion time.②The protective effect of MT was time-and dose-dependent when its concentration was not higher than 10 μmol/L.⑧When neurons were exposed to OGD for 90 minutes.part of the cells exhibited typical features of apoptosis:internucleosomal DNA condensation and DNA ladder on agarose gel electrophoresis.MT added to cells recovering from OGD exerted neuroprotective action against OGD-induced apoptosis.④In OGD exposed cultures,the production of MDA burst 12 hours after OGD,while MT significantly decreased the generation of MDA(P<0.05)in a time-dependent manner.CONCLUSION: MT may have therapeutic potential in the prevention and treatment of ischemic/hypoxic neuronal damage,and this neuroprotective action may contribute to the antioxidant nature of MT. | Ximing Wang Zhiqiang Lu Qiuhong Duan Tao Lu Shanshu He | 2006 | Neural Regeneration Research2006，1，7： | 0 |
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