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486篇 您的检索式:作者名="Sharma R H"
    题名 作者 年代 出处 被引量
12018加拿大心境障碍与焦虑障碍治疗协作组/国际双相障碍学会指南:双相障碍的管理显示文摘加拿大心境障碍与焦虑障碍治疗协作组(Canadian Network for Mood and Anxiety Treatments,CANMAT)曾于2005年发布了第1版双相障碍管理指南,并分别于2007、2009和2013年对该指南进行了更新,其中最近的2次更新是与国际双相障碍学会(International Society for Bipolar Disorders,ISBD)合作完成。2018版CANMAT/ISBD双相障碍治疗指南(以下简称指南)反映了自2005年首版指南发表以来本领域取得的重大进展,包括疾病诊断与疾病管理的更新以及药物治疗与心理治疗的近期研究进展。这些前沿进展中综合考虑了循证证据的级别,并基于治疗疗效、临床实践经验、安全性、耐受性和药物导致的转相风险等,对一线、二线及三线治疗方案进行了简明而清晰的推荐。本指南中新增内容涵盖了双相Ⅰ型障碍(BD-Ⅰ)的躁狂发作急性期、抑郁发作急性期和双相障碍维持期的一线及二线治疗推荐等级划分。这种对治疗推荐等级的划分综合考虑了治疗方法对双相障碍不同时相的影响,将进一步帮助临床医生做出基于循证证据的治疗决策。锂盐、喹硫平、双丙戊酸盐、阿塞那平、阿立哌唑、帕利哌酮、利培酮和卡利拉嗪单药或联合使用被推荐为躁狂发作急性期的一线治疗选择。BD-Ⅰ抑郁期的一线治疗选择包括喹硫平、鲁拉西酮、锂盐、拉莫三嗪单药,鲁拉西酮联合锂盐或双丙戊酸盐或拉莫三嗪辅助治疗。尽管急性期治疗有效的药物通常应继续用于BD-Ⅰ的维持期治疗,但也存在一些特殊情况(例如抗抑郁药)。现有数据表明,锂盐、喹硫平、双丙戊酸盐、拉莫三嗪、阿塞那平和阿立哌唑单药或联合治疗应被视为维持治疗的初始或更换治疗方案时的一线选择。除了探讨BD-Ⅰ的相关问题外,本指南中还对双相Ⅱ型障碍(BD-Ⅱ)的临床管理进行了系统回顾并给予治疗推荐,同时针对特殊人群也有相关推荐,如处于各个生殖周期的女性、儿童、青少年和老年人。此外,本指南中还讨论了特定精神疾病及共病(如物质滥用、焦虑障碍和代谢性疾病)的影响。最后,本指南中概述了安全性和药物监测的相关问题。CANMAT/ISBD工作组希望本指南能够成为全球临床医生的实用工具。Lakshmi N Yatham Sidney H Kennedy Sagar V Parikh Ayal Sehaffer David J Bond Benicio N Frey Verinder Sharma Benjamin I Goldstein Soham Rej Serge Beaulieu Martin Alda Glenda MaeQueen Roumen V Milev Arun Ravindran Claire O'Donovan Diane Mclntosh Raymond W Lam Gustavo Vazquez Flavio Kapczinski Roger S Melntyre Jan Kozicky Shigenobu Kanba Beny Lafer Trisha Suppes Joseph R Calabrese Eduard Vieta Gin Malhi Robert M Post Michael Berk 胡晨(译) 王刚(译) 2019中华精神科杂志2019,52,1:25
2具有低动脉粥样硬化风险特征的专业耐力运动员的亚临床冠状动脉疾病发病率显示文摘研究表明,具有冠状动脉疾病(coronary artery disease,CAD)危险因素的中老年(健将)运动员比久坐个体冠状动脉钙化(coronary artery calcium,CAC)评分更高。尚没有研究评估具有低动脉粥样硬化风险特征的专业运动员的CAD患病率。刘莉 叶鹏 Merghani A Maestrini V Rosmini S Cox AT Dhutia H Bastiaenen R David S Yeo TJ Narain R Malhotra A Papadakis M Wilson MG Tome M AlFakih K Moon JC Sharma S 2017中华高血压杂志2017,25,6:8
3Transurethral prostate re- section and bleeding:a randomized, placebo controlled trial of role of finasteride for decreasing operative blood loss显示文摘Donohue JF Sharma H Abraham R 2002J Urol2002,168,5:1
4Visual interpretation of hand gestures for human-computer interaction: a review显示文摘Pavlovic V I Sharma R Huang H S 1997IEEE Transactions on Pattern Analysis and Machine Learning1997,19,7:1
5Mutation in OsLMS, a gene encoding a protein with two double-stranded RNA binding motifs, causes lesion mimic phenotype and early senescence in rice ( Oryza sativa )显示文摘Undan J Tamiru M Abe A Yoshida K Kosugi S Takagi H Yoshida K Kanzaki H Saitoh H Fekih R Sharma S Undan J Yano M Terauchi R 2012Genes Genetic System2012,87,3:1
6Effect of wheat cultivar mixtures on spot blotch (Bipolaris sorokiniana) and grain yield 显示文摘SHARMA R C DUBIN H J 1996Field Crops Research1996,48,23:1
7Studies on pendimethalin and fluchloralin residues in soil and onion 显示文摘Sharma R Mehta H M 1989Indian J Agron1989,34,2:1
8Three-Di- mensional Analysis of Microstruetures in Titanium显示文摘Sharma H Van Bohemen S M C Petrov R H 2010Acta Ma- terialia2010,58,7:1
9Growth and characterization of carbon-supported MnO2 nanorods for super capacitor electrode显示文摘SHARMA R K OH H S SHUL Y G KIM H 0,,:1
10Antimicrobial activity of human beta-defensin 4 analogs: insights into the role of disulfide linkages in modulating activity显示文摘Sharma H Nagaraj R 2012Peptides2012,38,2:1
11Economic evaluation of ecosystem goods and services under different landscape management scenarios 显示文摘BARAL H KEENAN R J SHARMA S K 2014Land Use Policy2014,39,:1
12显示文摘Pramod K Sharma Jilavi M H Nass R 1999Journal of Luminescence1999,82,:1
13Role of dynamic flow in relationships between suction head and degree of saturation显示文摘MOHAMED M H A SHARMA R S 2007Journal of GeotechnicalandGeoenvironmentalEngineering2007,133,3:1
14Synthesis and physi- cal properties of isostearic acids and their esters 显示文摘Ngo H L Dunn R O Sharma B 2011Euro- pean Journal of Lipid Science and Technology2011,113,2:1
15Spinal cord and spinal nerve root involvement (myeloradiculopathy) in tuberculous meningitis显示文摘GUPTA R GARG R K JAIN A MALHOTRA H S VERMA R SHARMA P K 2015Medicine (Baltimore)2015,94,:1
16Electroless nickel plating on magnesium ahoy 显示文摘Sharma A K Suresh M R Bhojraj H 1998Metal Finishing1998,43,3:1
17Heavy metal induced accumulation of free proline in a metal-tolerant and a nontolerunt ecotype of Silene vulgaris显示文摘Schat H Sharmas S Voous R 1997Physiologic Plant1997,101,:1
18An experimental investigation of LNAPL migration in an unsaturated/saturated sand显示文摘Sharma R S Mohamed H A 2003Engineering Geology2003,70,:1
19Transuretheral pros- tate resection and bleeding: a randomized, placebo con- trolled trim of the role of finaste-ride for decreasing op- erative blood loss显示文摘Donahue JF Sharma H Abraham R 2002J Urol2002,168,:1
20Standard endoscopy with random biopsies versus narrow hand imaging targeted biopsies in Barrett's esophagus: a prospective, international, randomised controlled trial 显示文摘Sharma P Hawes R H Bansal A 2013Gut2013,62,1:1
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