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| 1 | White matter hyperintensity progression is associated with incident probable dementia or mild cognitive impairment显示文摘Background White matter hyperintensity(WMH)on brain MRI is associated with developing dementia or mild cognitive impairment(MCI),but WMH progression over time has not been fully investigated as an independent risk factor.Methods We performed a post hoc analysis of the Systolic Blood Pressure Intervention Trial-Memory and Cognition in Decreased Hypertension(SPRINT MIND)trial.The primary outcome was incident probable dementia or MCI(dementia/MCI)before the follow-up MRI at 48 months from enrolment.The primary predictor was WMH progression,defined as the Z score difference between the follow-up and baseline WMH volumes.The secondary predictor was a binary WMH progression threshold(≥1.4 mL vs<1.4 mL).Results Among the 433 included patients,33(7.6%)developed dementia/MCI.There were 156(36.0%)patients who met the WMH progression threshold of≥1.4 mL,in whom the rate of dementia/MCI was 12.8%(20/156)vs 4.7%(13/277)of patients with<1.4 mL WMH progression(p=0.002).In multivariable logistic regression,the Z score of WMH progression was associated with dementia/MCI(OR 1.51,95%CI 1.12 to 2.04,p=0.007)as was the WMH progression threshold of≥1.4 mL(OR 2.89,95%CI 1.23 to 6.81,p=0.015).Conclusions In this post hoc analysis of SPRINT MIND,WMH progression over 48 months was associated with the development of probable dementia or MCI. | Adam de Havenon Kevin N Sheth Sharon D Yeatts Tanya N Turan Shyam Prabhakaran | 2022 | Stroke & Vascular Neurology2022，7，4： | 2 |
| 2 | X-linked retinitis pigmentosa: mutation spectrum of the RPGR and RP2 genes and correlation with visual function显示文摘 | Sharon D Bruns GAP McGee TL Sandberg MA Berson EL Dryja TP | 2000 | Invest Ophthalmol Vis Sci2000，41，9： | 1 |
| 3 | Reactive-power definitions and power-fact or improvement in nonlinear systems显示文摘 | Sharon D | 1973 | Proceedings of the Institution of Electrical Engineers1973，120，6： | 1 |
| 4 | Factors Contrib- uting to Anxious Driving Behavior:The Role of Stress History and Accident Severity 显示文摘 | Joshua DC Shira AO Sharon D | 2011 | Journal of Anxiety Disorders2011，25，4： | 1 |
| 5 | Preventing the Sex-ual Transmission of HIV-1 with Topical Microbicides:Another Piece of the Equation显示文摘 | Lisa C R Sharon L H Charlene S D | 2007 | EDITORIAL COM-MENTARY2007，96，： | 1 |
| 6 | Vitamin D metabolites and analogs induce lipoxygenase mRNA expression and activity as well as reactive oxygen species (ROS) production in human bone cell line显示文摘 | Somjen D Katzburg S Grafi-Cohen M Knoll E Sharon O Posner GH | 2011 | J Steroid Biochem Mol Biol2011，123，12： | 1 |
| 7 | Hierarchy and adaptivity in segmenting visual scenes 显示文摘 | SHARON E GALUN M SHARON D | 2006 | Nature2006，442，7104： | 1 |
| 8 | Macro/micro manipulator: An improved architecture for robot control显示文摘 | SHARON A HOGAN N HARDT D E | 1993 | Robotics and Computer-Integrated Manufacturing1993，10，3： | 1 |
| 9 | Retinitis pigmentosa and allied diseases: numerous diseases, genes, and inheritance patterns显示文摘 | Rivolta C Sharon D Deangelis M M | 2002 | Hum Mol Genet2002，11，10： | 1 |
| 10 | Vitamin D analogs induce lipoxygenase mRNA expression and activity as well as reactive oxygen species (ROS) production in human bone cells显示文摘 | Somjen D Katzburg S Knoll E Sharon O Posner GH Stern N | 2010 | J Steroid Biochem Mol Biol2010，121，12： | 1 |
| 11 | Oxidation of dimethyl sulfoxide solutions by electrochemical reduction of oxygen 显示文摘 | Sharon D Afri M Noked M | 2013 | The Journal of Physical Chemistry Letters2013，4，18： | 1 |
| 12 | The distribution of wind - driven rainfall in a small valley: an empirical basis for numerical model verification显示文摘 | Sharon D Arazi A | 1997 | Hydrol1997，201，： | 1 |
| 13 | Adherence of Escherichia coli to human mucosal cells mediated by mannose receptors显示文摘 | Ofek I Mirelman D Sharon N | 1977 | Nature1977，265，： | 1 |
| 14 | Retinitis pigmentosa and allied diseases:numerous diseases,genes,and inheritance patterns显示文摘 | RIVOLTA C SHARON D DEANGELIS M M | 2002 | Hum Mol Genet2002，11，10： | 1 |
| 15 | Anti-adhesion therapy of bacterial diseases:prospects and problems显示文摘 | OFEK I HASTY D L SHARON N | 2003 | FEMS Immunol Med Microbiol2003，38，： | 1 |
| 16 | One-leg balance is an important predictor of injurious falls in older persons显示文摘 | BRUNO J VELLAS M D SHARON J | 1997 | J Am Geriatr Soc1997，45，6： | 1 |
| 17 | Trends in antibiotic use in massachusetts children, 2000-2009显示文摘 | Sharon K Greene Kenneth P Kleinman Matthew D | 2012 | Pediatrics2012，130，7： | 1 |
| 18 | Retinitis pigmentosa and allied diseases:numerous diseases,genes,and inheritance patterns显示文摘 | Rivolta C Sharon D DeAngelis MM | | 0，，10： | 1 |
| 19 | Anti-adhesion therapy of bacterial diseases:prospects and problems显示文摘 | Ofek I Hasty D L Sharon N | 2003 | FEMS Immunol Med Microbiol2003，38，： | 1 |
| 20 | Aqueous shunt devices compared with trabeculectomy with Mitomycin-C for children in the first two years of life显示文摘 | Allen D Beck Sharon Freedman Jeffrey Kammer Jing Jin | 2003 | American Journal of Ophthalmology2003，，6： | 1 |
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