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| 1 | Mandibular lateral incisor with four root canals: A unique case of double tooth diagnosed using multidetector computed tomography显示文摘 | Gupta Sunil Kumar GuptaJaya Acharya Shashi Rashmi Ather Amber | 2013 | Imaging science in dentistry2013，43，06： | 1 |
| 2 | Andrographolide inhibits chikungunya virus infection by up-regulating host innate immune pathways显示文摘Objective: To investigate the therapeutic efficacy of andrographolide, a plant derived compound, against chikungunya virus(CHIKV) infection. Methods: Using flow cytometry and immunoblotting assay, in vitro viral protein expression was studied in THP-1 cells line. In Balb/c mouse neonates, viral RNA copy number was determined by real time PCR. Results:The results showed reduced CHIKV protein expression on andrographolide treatment in CHIKV-infected human peripheral blood mononuclear cells, Vero cells and THP-I cell line.In vivo, andrographolide treatment to CHIKV-infected neonates reduced viral RNA copy number. Further. andrographolide also increased cytotoxic T lymphocytes both in vitro and in vivo. Andrographolide also activated host innate immune pathways, viz., protein kinase R.phosphorylated eukaryotic initiation factor 2 α, retinoic acid inducible gene-Ⅰ and interferon regulatory factor 3/7, thereby increasing IFN-a secretion. CHIKV-induced nuclear factor κlight chain enhancer of activated B cells and tumor necrosis factor-a was also reduced on andrographolide treatment. Conclusion: Andrographolide inhibits CHIKV by suppressing viral protein expression and up-regulating host innate immunity and hence could be an effective therapeutic agent against CHIKV infection. | Swati Gupta Kamla Prasad Mishra Paban Kumar Dash Manmohan Parida Lilly Ganju Shashi Bala Singh | 2018 | Asian Pacific Journal of Tropical Medicine2018，11，3： | 1 |
| 3 | Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy显示文摘 | Bang Claudia Batkai Sandor Dangwal Seema Gupta Shashi Kumar Foinquinos Ariana Holzmann Angelika Just Annette Remke Janet Zimmer Karina Zeug Andre Ponimaskin Evgeni Schmiedl Andreas Yin Xiaoke Mayr Manuel Halder Rashi Fischer Andre Engelhar | 2014 | Journal of Clinical Investigation2014，，： | 1 |
| 4 | Needs of Green Buildings Innovation and Implementation Flexibility for Prompt Effectiveness in Developing Countries显示文摘The construction concept is upgrading every year and major concern is given to the environment and human health.People’s activities for the sophistication has really degraded the component of environment which has impact in global warming,heat island effect and other hazardous effect causing negative impact to human health as well as environment.Now this trend need be changed and any construction work must be in collaboration with environment which is also coined as Green Building concept.In spite of many organizations’s effort this technology is being limited to some developed countries and no major progress is concluded in specially developing countries.Lack of awareness and misconception about the green building is limiting this concept.In order to make the green world very soon the system must be commenced from the government level itself.Government of every country should make grounds rules making basic green building categories and should register those building which have fulfilled the basic categories and certification must be given from government level itself evaluating the categories(Sustainable site development,Water saving,Energy efficiency,Material Selection,Indoor Environmental quality and Design)and innovation.Innovative design and implementation of engineering concept for every category must be given high priority.This paper forwards the concept of green buildings and basic categories which can be followed by government and basic planning design for everyone who can’t afford export which can be amend and implemented as per the context. | Shashi Kumar Gupta | 2023 | Journal of Civil Engineering and Architecture2023，17，7： | 0 |
| 5 | Geographic patterns of genetic diversity and fertility restoration ability of Asian and African origin pearl millet populations显示文摘A set of 45 diverse Asian and African origin/bred populations of pearl millet were investigated multi-locationally for morphological traits including grain yield and assessed for their fertility restoration ability on three cytoplasmic male sterility(CMS) systems in two contrasting seasons. Significant genetic variation was found for all the yield linked traits. Multivariate analysis for grain yield and its component traits grouped these populations into five clusters. Most of the Asian origin populations grouped into single cluster(Cluster III) and separated from the rest of the African origin populations indicating the presence of correspondence between clustering pattern and geographical origin of the populations. Clusters dominated with Asian populations(As-As) had linkages with early flowering, short plant height, more number of tillers, small and thin panicles, small seeded and low grain yield compared to the clusters dominated by African populations(Af-Af) or African origin and Asian bred(Af-As) populations.Genetically related populations having common parentage were found grouped in same clusters.Fertility restoration/maintainer frequency of 45 populations on three diverse CMS systems revealed that overall fertility restoration frequency was highest for A1(86%) followed by A4(37%) and for A5(7%) CMS system. Five populations were identified as potential sources for developing maintainer lines for all three CMS systems and eight populations were identified specifically for A;and A;CMS systems. A set of 11 and four populations were identified for restorer line development exclusively for A;and A;CMS system,respectively. Six populations were identified for the development of dual restorers for both A;and A;CMS system. | K.Sudarshan Patil Shashi Kumar Gupta | 2022 | The Crop Journal2022，10，2： | 0 |
| 6 | Phenotypic and molecular diversity-based prediction of heterosis in pearl millet(Pennisetum glaucum L.(R.)Br.)显示文摘Genetic distances between hybrid parents based on phenotypic traits and molecular markers were investigated to assess their relationship with heterosis for grain and stover yield and other traits in pearl millet(Pennisetum glaucum [L.] R. Br.). Fifty-one hybrids developed using 101 hybrid parents(B and R lines) and showing a wide range of genetic distance between their parents based on eight phenotypic traits and 28–38 SSRs were evaluated in two sets for two seasons. The correlation between Euclidean distance(phenotypic distance, ED) and simple matching distance(molecular distance, SM) for parents of both sets was low but positive and significant(r = 0.2, P < 0.001).The correlation of ED in parents with better-parent heterosis for grain yield was similar in both sets(r =0.38, P < 0.05). SM was not correlated with heterosis for grain yield in either set of hybrids.The results showed that phenotypic distance could be a better predictor of heterosis than molecular distance. The correlation between phenotypic distance and heterosis was not strong enough to permit the use of phenotypic diversity among parents as a major selection criterion for selection of parental lines displaying high levels of heterosis for grain and stover yield in pearl millet. | Shashi Kumar Gupta Thirunavukkarasu Nepolean Chinna Ghouse Shaikh Kedarnath Rai Charles Thomas Hash Roma Rani Das Abhishek Rathore | 2018 | The Crop Journal2018，6，3： | 0 |
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