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| 1 | Reactive mesoporous silica nanoparticles loaded with limonene for improving physical and mental health of mice at simulated microgravity condition显示文摘Astronauts are under high stress for a long time because of the microgravity condition,which leads to anxiety,affects their learning and memory abilities,and seriously impairs the health of astronauts.Aromatherapy can improve the physical and mental health of astronauts in a way that moisturizes them softly and silently.However,the strong volatility of fragrances and inconvenience of aroma treatment greatly limit their application in the field of spaceflight.In this study,reactive mesoporous silica nanoparticles were prepared to encapsulate and slowly release limonene.The limonene loaded nanoparticles were named limonene@mesoporous silica nanoparticles-cyanuric chloride(LE@MSNs-CYC).LE@MSNs-CYC were then applied to wallpaper to improve the convenience of aromatherapy.LE@MSNs-CYC could chemically react with the wallpaper,thus firmly adsorbed on the wallpaper.In the following,the mice were treated with hindlimb unloading(HU)to simulate a microgravity environment.The results showed that 28-day HU led to an increase in the level of anxiety and declines in learning,memory,and physical health in mice.LE@MSNs-CYC showed significant relief effects on anxiety,learning,memory,and physical health of HU treated mice.Subsequently,the molecular mechanisms were explored by hypothalamic-pituitary-adrenal axis related hormones,immune-related cytokines,learning,and memory-related neurotransmitters and proteins. | Zhiguo Lu Jianze Wang Lina Qu Guanghan Kan Tianlu Zhang Jie Shen Yan Li Jun Yang Yunwei Niu Zuobing Xiao Yinghui Li Xin Zhang | 2020 | Bioactive Materials2020，5，4： | 5 |
| 2 | High-temperature ultra-strength of dual-phase Re_(0.5)MoNbW(TaC)_(0.5) high-entropy alloy matrix composite显示文摘The dual-phase Re_(0.5)MoNbW(TaC)_(0.5) composite,consisting of refractory body-centered cubic(BCC)highentropy alloy and carbide with many fine eutectic structures,was successfully synthesized by arc melting.The phase stability,high-temperature mechanical properties and strengthening mechanism of the ascast composite were studied.The microstructure of the composite remained stable after annealing at 1300℃for 168 h.It exhibited remarkably high-temperature strength,yield strength~901 MPa,and true ultimate compressive strength~1186 MPa at 1200℃.The BCC phase and carbide exhibited a semi-coherent interface with good bonding after severe deformation at 1200℃.The dipolar dislocation walls in BCC phase,restricted dynamic interaction between defects in carbide,and the pinning effect of semi-coherent interface offered effective strengthening effects. | Qinqin Wei Guoqiang Luo RongTu Jian Zhang Qiang Shen Yujie Cui Yunwei Gui Akihiko Chiba | 2021 | Journal of Materials Science & Technology2021，，25： | 4 |
| 3 | Consumer Psychology Based Optimal Portfolio Design for Demand Response Aggregators显示文摘Demand response(DR)has received much attention for its ability to balance the changing power supply and demand with flexibility.DR aggregators play an important role in aggregating flexible loads that are too small to participate in electricity markets.In this work,a DR operation framework is presented to enable local management of customers to participate in electricity market.A novel optimization model is proposed for the DR aggregator with multiple objectives.On one hand,it attempts to obtain the optimal design of different DR contracts as well as the portfolio management so that the DR aggregator can maximize its profit.On the other hand,the customers’welfare should be maximized to incentivize users to enroll in DR programs which ensure the effective and flexible load control.The consumer psychology is introduced to model the consumers’behavior during contract signing.Several simulation studies are performed to demonstrate the feasibility of the proposed model.The results illustrate that the proposed model can ensure the profit of the DR aggregator whereas the customers’welfare is considered. | Yunwei Shen Yang Li Qiwei Zhang Fangxing Li Zhe Wang | 2021 | Journal of Modern Power Systems and Clean Energy2021，9，2： | 2 |
| 4 | Preparations of organobentonite using nonionic sur-factants显示文摘 | Shen Yunwei | 2001 | Chemosphere2001，44，5： | 1 |
| 5 | Removal of Chloride From Electric Arc Furnace Dust显示文摘 | Chen Weisheng Shen Yunwei Tsai M S | 2011 | Journal of Hazardous Materials2011，190，13： | 1 |
| 6 | Mesoporous silica nanospheres with the ability of photo-driven releasing sandela 803 for the application to wallpaper显示文摘Fragrances are widely used in our daily life and have made great contributions to creating a clean and fresh healthy air environment. However, the rapid volatilization severely influences their storage,application and quality. Therefore, it is necessary and urgent to develop approaches to controllably release the odorants as demanded. In this study, photo-driven mesoporous silica nanospheres loaded with sandela 803 was designed, prepared and named as S803@MS-S. S803@MS-S possessed ordered mesoporous, large specific surface area and pore volume. After adsorption of sandela 803, the S803@MSS was added into wallpaper to prepare fragrant wallpaper S803@MS-S-W. And this wallpaper exhibited excellent sustained and controlled release performances stimulated by light. | Weihong Ji Tianlu Zhang Zhiguo Lu Jie Shen Jing Hu Yunwei Niu Zuobing Xiao Xin Zhang | 2019 | Chinese Chemical Letters2019，30，3： | 1 |
| 7 | Preparation of hollow mesoporous silica nanorods for encapsulating and slowly releasing eugenol显示文摘Fragrances are widely used in many aspects of our lives.They cannot only make people happy,but also treat many diseases.However,excessively fast evaporation rate is one of the main obstacles to the use of spices.In this study,mesoporous silica nanorods(MSNRs)and hollow mesoporous silica nanorods(HMSNRs)were prepared to encapsulate eugenol.These two nano-fragrances were named eugenol@MSNRs and eugenol@HMSNRs,respectively.The morphologies,size,interior structures and pore performances of MSNRs and HMSNRs.Besides,the performances of encapsulation and fragrance release of eugenol@MSNRs and eugenol@HMSNRs were compared and analyzed.The results showed that eugenol@HMSNRs encapsulated more fragrance and were faster to encapsulate compared with eugenol@MSNRs.Both the release rates of eugenol from eugenol@MSNRs and eugenol@HMSNRs were slow.But the eugenol was released from eugenol@MSNRs more slowly. | Tianlu Zhang Zhiguo Lu Luyao Zhang Yan Li Jun Yang Jie Shen Jianze Wang Yunwei Niu Zuobing Xiao Lei Chen Xin Zhang | 2020 | Chinese Chemical Letters2020，31，12： | 0 |
| 8 | Cationic and temperature-sensitive liposomes loaded with eugenol for the application to silk显示文摘Silk has been widely used in the clothing industry due to their soft and smooth features,good biocompatibility,good heat dissipation,warmth and ultraviolet resistance.The application of fragrance to silk can significantly improve the performance of silk.However,there are two key scientific problems that need to be solved:slowing down the release rate of fragrances and increasing the scent lasting time of silk.In this study,cationic and temperature-sensitive liposomes were designed and prepared to encapsulate eugenol.These fragrance-loaded liposomes significantly slowed down the release rate of the fragrance and controlled the release rate of the fragrance in a thermo-sensitive manner.The liposomes adhered to the silk through electrostatic adsorption interaction.The positive charge on the fragranceloaded liposomes neutralized much negative charge on silk and thereby increasing the adhesion efficiency. | Zhiguo Lu Xiangyu Wang Tianlu Zhang Luyao Zhang Jun Yang Yan Li Jie Shen Jianze Wang Yunwei Niu Zuobing Xiao Guiying Liu Xin Zhang | 2020 | Chinese Chemical Letters2020，31，12： | 0 |
| 9 | Reactive nano-essential oils for sustained release of essential oils and application to wallpaper显示文摘Essential oils are a volatile and aromatic substance with a variety of active biological activities.However,the excessive volatility and inconvenience of the use of essential oils limit their applications.In this study,we developed a reactive mesoporous silica nanoparticle(rMSNs)based on cyanuric chloride modification for essential oil encapsulation and commodity adhesion.The large pore volume and specific surface area of rMSNs facilitate the nanoparticles adhering to a large amount of essential oil and achieve the sustained release of essential oil,thus prolonging the fragrance retention time of essential oils.The reactive nanoessential oils can form covalent bonds with the wallpaper,thereby remarkably improving the adhesion of the reactive nano-essential oils on the wallpaper and preventing the reactive nano-essential oil from deadhering from the wallpaper.The active nano essential oil simultaneously overcomes the intense volatility of the essential oil and inconvenience in use,has a simple preparation process and low cost,and has great application potential. | Qiulian Hao Huan Peng Ruichen Zhao Jianze Wang Zhiguo Lu Jingwen Wang Jie Shen Yunwei Niu Zuobing Xiao Guiying Liu Jifu Hao Xin Zhang | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 10 | Preparation of mesoporous silica nanoparticle with tunable pore diameters for encapsulating and slowly releasing eugenol显示文摘Fragrances are frequently added to a variety of products,including food,cosmetics and health products.However,the high volatility and instability of essence limit its application in some fields.In this study,mesoporous silica nanoparticles(MSNs) were prepared to encapsulate eugenol,which could reduce the volatilization of the fragrance molecules.A facile approach was presented to synthesize MSNs with three different pore diameters for encapsulating eugenol.In addition,the properties of MSNs including mean particle size,morphology,encapsulating efficiency and release tendency were charac terized.Results showed that the larger the pore diameters of MSNs,the more aromatic molecules were adsorbed.Furthermore,the release mechanism was described as the smaller the pore diameters of MSNs,the slower the release of eugenol. | Tianlu Zhang Zhiguo Lu Jianze Wang Jie Shen Qiulian Hao Yan Li Jun Yang Yunwei Niu Zuobing Xiao Lei Chen Xin Zhang | 2021 | Chinese Chemical Letters2021，32，5： | 0 |
| 11 | CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes显示文摘In this study,we identified that a conserved circular RNA(circRNA)DICAR,which was downregulated in diabetic mouse hearts.DICAR had an inhibitory effect on diabetic cardiomyopathy(DCM),as the spontaneous cardiac dysfunction,cardiac cell hypertrophy,and cardiac fibrosis occurred in DICAR deficiency(DICAR+/−)mice,whereas the DCM was alleviated in DICARoverexpressed DICARTg mice.At the cellular level,we found that overexpression of DICAR inhibited,but knockdown of DICAR enhanced the diabetic cardiomyocyte pyroptosis.At the molecular level,we identified that DICAR-VCP-Med12 degradation could be the underlying molecular mechanism in DICAR-mediated effects.The synthesized DICAR junction part(DICAR-JP)exhibited a similar effect to the entire DICAR.In addition,the expression of DICAR in circulating blood cells and plasma from diabetic patients was lower than that from health controls,which was consistent with the decreased DICAR expression in diabetic hearts.DICAR and the synthesized DICAR-JP may be drug candidates for DCM. | Qiong Yuan Yunwei Sun Fan Yang Dan Yan Meihua Shen Zhigang Jin Lin Zhan Guangqi Liu Ling Yang Qianyi Zhou Zhijun Yu Xiangyu Zhou Yang Yu Yong Xu Qingming Wu Jianfang Luo Xiamin Hu Chunxiang Zhang | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 0 |
| 12 | Zwitterionic comb-like lipid polymers encapsulating linalool for increasing the fragrance retention time显示文摘Fragrances are widely used in cosmetics,apparel and detergents.However,the rapid evaporation of the aro ma shortens the useful life of the aromatic product.Therefore,improving the fragrance retention time of aromatic products and prolonging the service life of aromatic products are the key scientific problems that need to be solved in current aromatic products.In this study,zwitterionic comb-like lipid polymers were synthesized to encapsulate the fragrance molecule linalool.The results showed that the zwitterionic comb lipid molecules were capable of encapsulating more linalool than linear lipid molecules.At the same time,the zwitterionic comb-like lipid molecules also limited the slow release rate of the aroma,thereby increasing the fragrance retention time of the nano-fragrance. | Tianlu Zhang Zhiguo Lu Xiangyu Wang Jie Shen Jianze Wang Yunwei Niu Zuobing Xiao Xin Zhang | 2021 | Chinese Chemical Letters2021，32，1： | 0 |
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