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| 1 | Common SNPs of APM1 Gene Are Not Associated With Hypertension or Obesity in Chinese Population显示文摘Objective To investigate whether the common variants 45T/G and 276G/T in APM1 gene were associated with hypertension combined with obesity (HO) and related clinical features in Chinese Han population. Methods A case-control study design was applied. Common polymorphisms of 45T/G and 276G/T were genotyped by PCR product sequencing in 484 cases with HO and 502 controls with normal blood presure and BMI < 25. Results The genotype and allele frequencies of 45T/G, 276G/T, and haplotype defined by the two variants in cases did not differ from those in controls. The means of blood pressure, BMI and waist-hip ratio did not differ among genotypes of the two polymorphisms and haplotypes. Among lipid profiles, only serum high-density lipoprotein cholesterol (HDL-C) levels were significantly lower in T allele carriers than that in non-T carriers after adjusting possible confounding factors (1.21 vs 1.32 mmol/L, P=0.0001). Conclusion Polymorphisms of 45T/G and 276G/T in APM1 gene are not associated with hypertension or obesity, or their clinical features in Chinese Han population. Common polymorphism of 45T/G might be associated with serum HDL-C levels in Chinese. | WEI-LI YAN SHU-FENG CHEN JIAN-FENG HUANG YAN SHENA BO-QIN QIANG DONG-HAI LIU DONG-FENG GU | 2006 | Biomedical and Environmental Sciences2006，19，3： | 13 |
| 2 | Engineering of drug nanoparticles by HGCP for pharmaceutical applications显示文摘This paper reviews our work on the fundamental principles of high gravity controlled precipitation (HGCP) technology, and its applications in the production of drug nanoparticles, which was carried out in a rotating packed bed (RPB). Several kinds of drug nanoparticles with narrow particle size distributions (PSDs) were successfully prepared via HGCP, including the 300-nm Cefuroxime Axetil (CFA) particles, 200–400-nm cephradine particles, 500-nm salbutamol sulfate (SS) particles (100 nm in width), and 850-nm beclomethasone dipropionate (BDP) particles, etc. Compared to drugs available in the current market, all the drug nanoparticles produced by HGCP exhibited advantages in both formulation and drug delivery, thus improving the bioavailability of drugs. HGCP is essentially a platform technology for the preparation of poorly water-soluble drug nanoparticles for oral and injection delivery, and of inhalable drugs for pulmonary delivery. Consequently, HGCP offers potential applications in the pharmaceutical industry due to its cost-effectiveness, efficient processing and the ease of scaling-up. | Ting-Ting Hua, Jie-Xin Wanga, Zhi-Gang Shena, Jian-Feng Chena,b, a Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, China b Research Center of Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, Beijing 100029, China | 2008 | Particuology2008，6，4： | 7 |
| 3 | Role of Non O-histone interaction in TNFα-suppressed prolyl-4-hydroxylaseα1显示文摘 | Zhang C Zhanga M X Shena Y H | 2008 | Biochim Biophys Acta2008，1783，8： | 1 |
| 4 | The Library as an Agency of Social Communication显示文摘 | Shena J H | 1965 | Journal of Documentation1965，，4： | 1 |
| 5 | Reverse micelles extraction of nattokinase from fermentation broth 显示文摘 | Liu Jun-Guo Xing Jian-Min Rui Shena | 2004 | Biochemical Engineering Journal2004，21，3： | 1 |
| 6 | Learning multi-label scene classification显示文摘 | Boutella M R Luo J Shena X | 2004 | Pattern Recognition2004，37，9： | 1 |
| 7 | Organizational approaches to the implementation of simultaneous engineering 显示文摘 | Shenas D G Derakhshan S | 1994 | International Journal of Operations & Production Management1994，14，： | 1 |
| 8 | Organizational approaches to the implementation of simultaneous engineering 显示文摘 | Shenas D G Derakhshan S | 1994 | International Journal of Operations & Production Management1994，14，： | 1 |
| 9 | Overview of DNA chip technology显示文摘 | Lemieux B Aharoni A Shena M | 1998 | Molecular Breeding1998，4，： | 1 |
| 10 | A hybrid selection model for emerging technology显示文摘 | SHENA YUNG-CHI CHANG SHU-HSUAN LINA G | 2010 | Technologieal Forecasting & Social Change2010，77，1： | 1 |
| 11 | Forecasting stock indices using radial basis function neural networks optimized by artificial fish swarm algorithm显示文摘 | Wei Shena Xiaopen Guoa | | 0，，03： | 1 |
| 12 | A rhodamine-appended water-soluble conjugated polymer:an efficient ratiometric fluorescence sensing platform for intracellular metal-ion probing显示文摘 | Wu Y X Li J B Zhang X B Tan W H Shena G L Yua R Q | 2014 | Chemical Communications2014，50，16： | 1 |
| 13 | Simulation of wave propagation over a submerged bar using the VOF method with a two-equation k-ε turbulence modeling显示文摘 | Shena Y M Ngb C O Zhengc Y H | | 0，，01： | 1 |
| 14 | Multivariate statistical study of heavy metal enrichment in sediments of the Pearl River Estuary显示文摘 | Liu W X Lia X D Shena Z G | 2003 | Environmental Pollution2003，21，： | 1 |
| 15 | Gene silencing by adenovims-delivered siRNA 显示文摘 | SHENA C X BUCKA A K LIUA K W | 2003 | FEBS Letters2003，539，： | 1 |
| 16 | The thermal performance of the polysaccharides extracted from hardwood: Cellulose and hemicellulose 显示文摘 | D K SHENA S GUA A V BRIDGWATER | 2010 | Carbohy- drate Polymers2010，82，1： | 1 |
| 17 | Using fire dynamic simulation (FDS) to reconstruct an arson fire seene显示文摘 | Tzu Sheng Shena Yu Hsiang Huangb Shen Wen Chien | 2008 | Building and Environment2008，43，： | 1 |
| 18 | Effects of particle size on the fast pyrolysis of oil mallee woody biomass显示文摘 | Jun Shena Xiao-Shan Wanga Manuel Garcia-Pereza Daniel Mouranta Martin J Rhodesa and Chun-Zhu Lia | 2009 | Fuel2009，10，88： | 1 |
| 19 | Photo-induced Alignment Behavior of Azobenzene-containing Polymer Films with Different Cross-linking Degree显示文摘与各种各样的取代者和交叉连接的某些数量包含偶氮苯组的非结晶的共聚物的三个系列有能力的丙烯酸的组被准备。cross-linked 聚合物电影被丙烯酸的组的热聚合在共聚物,由控制 cross-linking 反应的时间,这些电影能与不同 cross-linking 度在期间被做获得(从 0 ~ 32% ,它被英尺红外系列测量监视) 。这些电影的导致相片的排列过程在 442 nm 与线性地极化的光在照耀下面被执行,并且导致相片的排列率上的 cross-linking 度的效果被调查。导致相片的排列的动力学与双性人一起被分析指数的曲线试穿。因为 cross-linking,导致相片的排列率和这些电影的最大的发射度减少了。为 cross-linked 样品,在重复了“写”并且“擦掉”周期以后,而且,他们发射度的浸透的价值保持不变,这被发现。调查结果表明电影罐头的 cross-linking 有效地由极化的光在照耀期间制止偶氮的聚合物的趋光性的集体运输。在 cross-linking 度和偶氮的聚合物的导致相片的排列行为之间的关系详细被讨论。 | Jing Shena Jin-tang Huang Yan-hua Luoa Qi-jin Zhang Ke-yi Wang | 2008 | Chinese Journal of Chemical Physics2008，21，5： | 1 |
| 20 | Applying rough sets to market timing decisions显示文摘 | Lixiang Shena Han Tong Loh | 2004 | Decision Support Systems2004，37，： | 1 |
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