| 1 | Sinorhizobium meliloti NtrX interacts with different regions of the visN promoter显示文摘The bacterial flagellum is a motile organelle consisting of a transmembrane multi-protein apparatus composed of the flagellins, the flagellin export complex, and the basal body with motor proteins. Flagellum biosynthesis is regulated by a hierarchical system in Escherichia coli [1]. Different from E. coli, Sinorhizobium meliloti, as a plant-symbiotic soil bacterium, induces the formation of nitrogen-fixing root nodules on the host plant alfalfa when combined nitrogen is limited. Sinorhizobium meliloti contains a ‘flagellum regulon’ that consists of 41 genes, including 10 chemotaxis (che) genes, 4 motor (mot) genes, 15 flg, flh, and fli genes encoding the components of the protein export complex and the basal body, 4 flagellin (fla) genes, and 4 unknown genes [1]. Similar to E. coli, flagellum biosynthesis in S. meliloti depends on a hierarchical system that is composed of the Class IA regulators, VisN and VisR, the Class IB regulator, Rem, Class II FliM, MotABC, and Class III flagellin and chemotaxis proteins [2]. Recently, several other regulators involved in flagellum biosynthesis have been reported, including the tow-component regulatory system ExoS/ChvI with the suppressor ExoR and the LuxR regulator ExpR in S. meliloti [3,4]. | Shuang Zeng Shenghui Xing Fang An Xinwei Yang Junhui Yan Liangliang Yu Li Luo | 2020 | Acta Biochimica et Biophysica Sinica2020，52，8： | 0 |
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