|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Impact of topical nonsteroidal anti-inflammatory drugs in prevention of macular edema following cataract surgery in diabetic patients显示文摘AIM: To evaluate the efficacy of prophylactic administration of topical non-steroidal anti-inflammatory drugs(NSAIDs) on macular edema following cataract surgery in diabetic patients, and to compare between types of NSAIDs(ketorolac tromethamine 0.4% and nepafenac 0.1%). METHODS: Group 1(control) received artificial tears substitute as a placebo group, group 2(nepafenac) received topical nepafenac 0.1%, and group 3(ketorolac) received topical ketorolac tromethamine 0.4%. Patients were examined postoperatively after completing one week, one month, two months and three months' intervals for evaluating cystoid macular edema(CME) development. The main study outcomes were achieving the best corrected visual acuity(BCVA) and change in the central macular thickness(CMT) measured with optical coherence topography(OCT).RESULTS: Eighty eyes of 76 patients were included in this study. BCVA showed a statistically significant difference at the third month postoperative follow up between the control group and the NSAIDs groups(P=0.04). There was an increase in the CMT in all cases starting from postoperative first week until third month. CMT showed a statistically significant difference between control group and NSAIDs groups from postoperative first month until third month(P=0.008, 0.027, 0.004). There was no statistically significant difference between nepafenac and ketorolac groups in BCVA and OCT CMT. CONCLUSION: Prophylactic preoperative and postoperative NSAIDs may have a role in reducing the frequency and severity of CME in diabetic eyes following cataract surgery. | Ahmed A.Alnagdy Hossam Y.Abouelkheir Sherief E.El-Khouly Sahar M.Tarshouby | 2018 | International Journal of Ophthalmology(English edition)2018，11，4： | 13 |
| 2 | Idiopathic fistula-in-ano显示文摘Fistula-in-ano is the most common form of perineal sepsis.Typically,a fistula includes an internal opening,a track,and an external opening.The external opening might acutely appear following infection and/or an abscess,or more insiduously in a chronic manner.Management includes control of infection,assessment of the fistulous track in relation to the anal sphincter muscle,and finally,definitive treatment of the fistula.Fistulotomy was the most commonly used mode of management,but concerns about post-fistulotomy incontinence prompted the use of sphincter preserving techniques such as advancement flaps,fibrin glue,collagen fistula plug,ligation of the intersphincteric fistula track,and stem cells.Many descriptive and comparative studies have evaluated these different techniques with variable outcomes.The lack of consistent results,level I evidence,or long-term follow-up,as well as the heterogeneity of fistula pathology has prevented a definitive treatment algorithm.This article will review the most commonly available modalities and techniques for managing idiopathic fistula-in-ano. | Sherief Shawki Steven D Wexner | 2011 | World Journal of Gastroenterology2011，17，28： | 7 |
| 3 | Helicobacter pylori may be an initiating factor in newly diagnosed ulcerative colitis patients: A pilot study显示文摘AIM To directly visualize Helicobacter pylori(H. pylori) by the highly sensitive and specific technique of immunohistochemical staining in colonic tissue from patients newly diagnosed with ulcerative colitis(UC).METHODS Colonoscopic biopsies from thirty patients with newly diagnosed UC and thirty controls were stained with Giemsa stain and immunohistochemical stain for detection of H. pylori in the colonic tissue. Results were confirmed by testing H. pylori Ag in the stool then infected patients were randomized to receive either anti H. pylori treatment or placebo.RESULTS Twelve/30(40%) of the UC patients were positive for H. pylori by Giemsa, and 17/30(56.6%) by immunohistochemistry stain. Among the control group 4/30(13.3%) and 6/30(20 %) were positive for H. pylori by Giemsa and immunohistochemistry staining respectively. H. pylori was significantly higher in UC than in controls(P = 0.04 and 0.007). All Giemsa positive patients and controls were positive by immunohistochemical stain. Four cases of the control group positive for H. pylori also showed microscopic features consistent with early UC.CONCLUSION H. pylori can be detected in colonic mucosa of patients with UC and patients with histological superficial ulcerations and mild infiltration consistent with early UC. There seems to be an association between UC and presence of H. pylori in the colonic tissue. Whether this is a causal relationship or not remains to be discovered. | Loai Mansour Ferial El-Kalla Abdelrahman Kobtan Sherief Abd-Elsalam Mohamed Yousef Samah Soliman Lobna Abo Ali Walaa Elkhalawany Ibrahim Amer Heba Harras Maha M Hagras Mohamed Elhendawy | 2018 | World Journal of Clinical Cases2018，6，13： | 4 |
| 4 | Challenges in COVID-19 drug treatment in patients with advanced liver diseases:A hepatology perspective显示文摘The global incidence of coronavirus disease 2019(COVID-19)continues to increase despite health care efforts.The disease is caused by coronavirus 2 with high transmission and mortality rates.Little is known about the management of COVID-19 in advanced liver disease.The aim of work was to propose a plan for management of this drastic disease in case of this specific population with review of medications that could be suitable for advanced liver disease.All the guidelines and medications available for treatment of COVID-19 were reviewed with selection of the less toxic medications that could be used in advanced liver disease.Drugs suitable to manage COVID-19 in patients with liver disease might include remdesivir intravenously,nitazoxanide+sofosbuvir,ivermectin,tocilizumab,convalescent plasma,and low molecular weight heparin in certain situations.Advanced liver disease is associated with portal hypertension and splenomegaly with reduction of blood elements and immune dysfunction and impaired T cell function.Thus,when confronted by cytokine storm as an immune response to COVID-19,there may be an increase in the mortality rate of these patients.Through this review,a plan to treat COVID-19 in this special group of patients with advanced cirrhosis is proposed. | Amr Shaaban Hanafy Sherief Abd-Elsalam | 2020 | World Journal of Gastroenterology2020，26，46： | 4 |
| 5 | Functional and anatomical evaluation of the effect of nepafenac in prevention of macular edema after phacoemulsification in diabetic patients显示文摘AIM: To evaluate the effect of prophylactic administration of nepafenac in prevention of macular edema occurring in diabetic patients after phacoemulsification and to investigate the correlation between optical coherence tomography(OCT) foveal thickness and multifocal electroretinogram(MF-ERG) parameters.METHODS: The study included two groups. Group 1 included 50 diabetic patients with senile cataract(50 eyes, 30 females, 20 males, aged 55±7 y) received nepafenac 0.1% eye drop. Group 2 included another 50 diabetic patients with senile cataract(50 eyes, 22 female, 28 males, aged 53.8±8 y) did not receive nepafenac. All patients were followed up for 3 mo postoperatively. OCT and MF-ERG were done preoperative and at 1 wk, 1, 2 and 3 mo.RESULTS: The mean foveal thickness was statistically significantly lower in Group 1. Five eyes in Group 2 developed clinical cystoid macular oedema(CMO)(10%), and no patients in Group 1 developed central macular thickening more than 50 μm. There were insignificant differences in MF-ERG amplitudes and latencies between the two groups except in the five eyes that developed CMO, there statistically significant reduction of MF-ERG amplitude with increase in foveal thickness. CONCLUSION: Perioperative nepafenac reduces the incidence of CMO following uncomplicated phacoemulsification significantly. Nepafenac has no side effects. | Tharwat Mokbel Sameh Saleh Mona Abdelkader Sherief E.El-khouly Waleed Abou Samra Mohamed Mamdouh | 2019 | International Journal of Ophthalmology(English edition)2019，12，3： | 3 |
| 6 | Visual performance after implantation of two types of phakic foldable intraocular lenses for correction of high myopia显示文摘AIM: To compare Visian lens(model V4 c) and Artiflex lens regarding quality(contrast sensitivity) and quantity(efficacy, predictability, safety and stability) of vision in correcting high myopia with recording and analysis of complications. METHODS: The comparative prospective study included 39 eyes of 23 patients with high myopia, 19 eyes had Visian lens implantation(model V4 c) and 20 eyes had Artiflex lens implantation. The inclusion criteria were high myopia(higher than 6.0 D) and stable refraction(<0.5 D change over one year). Outcomes included assessment of safety and efficacy indices, predictability, stability, contrast sensitivity and analysis of complications at postoperative 1 d, 1 wk and 1, 3, 6 and 12 mo. Selection of the type of phakic intraocular lens for patients was based on surgeons' preferences, which was no specific selection criteria. RESULTS: After 12 mo of follow up, difference in uncorrected and corrected distant visual acuity(CDVA) between both groups was statistically insignificant(UDVA for VisianV4 c and Artiflex lens were 0.33±0.2 logMAR and 0.37±0.2 logMAR respectively, P=0.59, CDVA for VisianV4 c and Artiflex lens were 0.155±0.1 logMAR and 0.147± 0.1 logMAR respectively, P=0.87). The efficacy index was 1.25 for VisianV4 c lens and 0.8 for Artiflex lens, 78.9% of eyes were within one diopter spherical equivalent in Visian V4 c lens group compared to 70% in the Artiflex lens group. No eye lost lines of CVDA proving a good safety index for both lenses(safety index was 1.67 for VisianV4 c lens and 1.34 for Artiflex lens). Difference in contrast sensitivity between both groups was statistically insignificant(P=0.15, 0.88, 0.27, 0.32 and 0.82 at five spatial frequencies). CONCLUSION: Both Visian ICL V4 c and Artiflex lensesare safe and effective with stable and predictable refraction and they have comparable contrast sensitivity outcomes with no vision threatening complications. | Islam M.Rizk Abd-Almonem A.Al-hessy Sherief E.El-Khouly Ashraf M.Sewelam | 2019 | International Journal of Ophthalmology(English edition)2019，12，2： | 3 |
| 7 | In vitro and in vivo effects of ferulic acid on gastrointestinal motility:Inhibition of cisplatin-induced delay in gastric emptying in rats显示文摘AIM: To study the effects of ferulic acid on gastrointe-stinal motility both in vitro and in vivo.METHODS: Ferulic acid induced concentration-dependent stimulation of the basal tone of isolated guinea pig ileum (2-20 μmol/L) and isolated rat fundus (0.05-0.4 mmol/L). RESULTS: Ferulic acid significantly accelerated the gastrointestinal transit and gastric emptying in rats in a dose-dependent manner (50-200 mg/kg, po). Cisplatin (2.5-20 mg/kg, ip) induced a dose-dependent delay in gastric emptying in rats. Pretreatment with ferulic acid dose-dependently, significantly reversed the cisplatin-induced delay in gastric emptying. CONCLUSION: The endogenous prostaglandins (PGs) are involved in mediating the stimulant effects of ferulic acid. This effect of dietary ferulic acid may help improve other accompanying gastrointestinal symptoms such as abdominal discomfort and also may protect against emesis induced by cytotoxic drugs. | Osama A Badary Azza S Awad Mohey A Sherief Farid MA Hamada | 2006 | World Journal of Gastroenterology2006，12，33： | 2 |
| 8 | Towards hepatitis C virus elimination:Egyptian experience,achievements and limitations显示文摘Worldwide, more than one million people die each year from hepatitis C virus(HCV) related diseases, and over 300 million people are chronically infected with hepatitis B or C. Egypt used to be on the top of the countries with heavy HCV burden. Some countries are making advances in elimination of HCV, yet multiple factors preventing progress; remain for the majority. These factors include lack of global funding sources for treatment, late diagnosis, poor data, and inadequate screening. Treatment of HCV in Egypt has become one of the top national priorities since 2007. Egypt started a national treatment program intending to provide cure for Egyptian HCV-infected patients. Mass HCV treatment program had started using Pegylated interferon and ribavirin between 2007 and 2014. Yet, with the development of highly-effective direct acting antivirals(DAAs) for HCV, elimination of viral hepatitis has become a real possibility. The Egyptian National Committee for the Control of Viral Hepatitis did its best to provide Egyptian HCV patients with DAAs. Egypt adopted a strategy that represents a model of care that could help other countries with high HCV prevalence rate in their battle against HCV. This review covers the effects of HCV management in Egyptian real life settings and the outcome of different treatment protocols. Also, it deals with the current and future strategies for HCV prevention and screening as well as the challenges facing HCV elimination and the prospect of future eradication of HCV. | Dalia Omran Mohamed Alboraie Rania A Zayed Mohamed-Naguib Wifi Mervat Naguib Mohamed Eltabbakh Mohamed Abdellah Ahmed Fouad Sherief Sahar Maklad Heba Hamdy Eldemellawy Omar Khalid Saad Doaa Mohamed Khamiss Mohamed El Kassas | 2018 | World Journal of Gastroenterology2018，24，38： | 2 |
| 9 | Photophysics and dynamics of coumarin laser dyes and their analytical implications显示文摘 | M S A Abdel-Mottaleb M S Antonious M M Abo Ali L F M Ismail B A El-Sayed A M K Sherief | 1992 | Proceedings of the Indian Academy of Sciences - Chemical Sciences1992，，2： | 1 |
| 10 | A two-dimensional thermoelasticity problem for a half space subjected to heat sources显示文摘 | Sherief H H Megahed F A | 1999 | Internat J Solids and Structures1999，36，9： | 1 |
| 11 | Biomarkers and early detection of late onset ant hracycline-induced cardiotoxicity in children显示文摘 | Sherief LM Kamal AG Khalek EA | 2012 | Hematology2012，17，3： | 1 |
| 12 | Cinacalcet in pediatric and adolescent chronic kidney disease显示文摘 | Alharthi AA Kamal NM Sherief LM | 2013 | Medicine(Baltimore)2013，94，2： | 1 |
| 13 | Lisfranc injury:how frequently does it get missed? And how can we improve?显示文摘 | Sherief TI Mucci B Greiss M | 2007 | Injury2007，38，7： | 1 |
| 14 | A periodic structure in the 'pen' chitin of the squid Loligo vulgaris 显示文摘 | HUNT S SHERIEF A E L | 1990 | Tissue and Cell1990，22，2： | 1 |
| 15 | Nt-probnp as early marker of subclinical late cardiotoxicity after doxorubicin therapy and medi- astinal irradiation in childhood cancer survivors 显示文摘 | Zidan A Sherief LM El-sheikh A | 2015 | Disease mark- ers2015，2015，： | 1 |
| 16 | Biomarkers and early detection of late onset anthracycline-induced cardiotoxicity in children显示文摘 | Sherief LM Kamal AG Khalek EA | 2012 | Hematology2012，17，3： | 1 |
| 17 | Fractional order theory of thermoelasticity 显示文摘 | Sherief H H E1-Sayed A M A Abd E1-Latief A M | 2010 | International Journal of Solids and Structures2010，47，2： | 1 |
| 18 | Fludamental solution of the generalized thermoelastic problem for short times 显示文摘 | Sherief H H | 1986 | J Thermal Stresses1986，9，2： | 1 |
| 19 | Lisfranc injury:how frequently does it get missed? And how can we improve显示文摘 | Sherief TI Mucci B Greiss M | | 0，，： | 1 |
| 20 | Biomarkers and early detection of late onset anthracycline-induced car- diotoxicity in children显示文摘 | SHERIEF LM KAMAL AG KHALEK EA | 2012 | Hematology2012，17，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员