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12篇 您的检索式:作者名="Sherif AM"
    题名 作者 年代 出处 被引量
1Ghrelin attenuates gastrointestinal epithelial damage induced by doxorubicin显示文摘AIM:To examine the influence of ghrelin on the regenerative potential of gastrointestinal(GI)epithelium.METHODS:Damage to GI epithelium was induced in mice by two intravenous injections of doxorubicin(10 and 6 mg/kg).Some of the doxorubicin-treated mice received a continuous subcutaneous infusion of ghrelin(1.25μg/h)for 10 d via implanted mini-osmotic pumps.To label dividing stem cells in the S-phase of the cell cycle,all mice received a single intraperitoneal injection of 5'-bromo-2'-deoxyuridine(BrdU)one hour before sacrifice.The stomach along with the duodenum were then removed and processed for histological examination and immunohistochemistry using anti-BrdU antibody.RESULTS:The results showed dramatic damage to the GI epithelium 3 d after administration of chemotherapy which began to recover by day 10.In ghrelintreated mice,attenuation of GI mucosal damage was evident in the tissues examined postchemotherapy.Immunohistochemical analysis showed an increase in the number of BrdUlabeled cells and an alteration in their distribution along the epithelial lining in response to damage by doxorubicin.In mice treated with both doxorubicin and ghrelin,the number of BrdUlabeled cells was reduced when compared with mice treated with doxorubicin alone.CONCLUSION:The present study suggests that ghrelin enhances the regenerative potential of the GI epithelium in doxorubicintreated mice,at least in part,by modulating cell proliferation.Mohamed A Fahim Hazem Kataya Rkia El-Kharrag Dena AM Amer Basel al-Ramadi Sherif M Karam 2011World Journal of Gastroenterology2011,17,33:3
2Quantitive a-nalysis of IL -10 and IFN -mRNA levels in normal cer-vix and human papillomavirous type 16 associated cervical precancer显示文摘EI -Sherif AM Seth R Tigher PJ 2001J Pathol2001,195,2:1
3Quantitative analysis of IL-10 and IFN-gamma mRNA levels in normal cervix and human papillomavirus type 16 associated cervical precancer 显示文摘El Sherif AM Seth R Tighe PJ 2001J Pathol2001,195,2:1
4Serum TGF-β,serum MMP-1,and HOMA-IR as non-invasive predictors of fibrosis in Egyptian patients with NAFLD显示文摘ADEL AM AMAL SB SHERIF SS 2012Saudi J Gastroenterol2012,18,5:1
5Quantitative assessment of the peritoneal vessel density and vasculopathy in CAPD patients显示文摘Sherif AM Nakayama M Maruyama Y 2006Nephrol Dial Transplant2006,21,6:1
6Basic aspects of GABA transmission in alcoholism,with particttlar refer- ence to GABA transaminase 显示文摘Sherif FM Tawati AM Ahmed SS 1997Eur Neuropsychopharma-col1997,7,1:1
7Quantitative analysis of IL-10 and IFN-gamma mRNA levels in normal cervix and human papillomavirus type 16 associated cervical precancet 显示文摘El Sherif AM Seth R Tighe PJ 2001J Pathol2001,195,2:1
8Instrumented forceps for measurement of nerve compression forces显示文摘Nawwar AM Sherif MF Barakat NG 1995J Biomech Eng1995,117,1:1
9Elucidation of the effects of a high fat diet on trace dements in rabbit tissues using atomic absorption spectroscopy显示文摘Mohamed AK Hisham AA Sherif AM 2010Lipids in Health and Disease2010,9,2:1
10Quanitative analysis of IL-10 and IFN-garnma mRNA levels in norman cervix and human papilloma virus type 16 associated cervical precancer 显示文摘EI Sherif AM Seth R Tighe PJ 2001J Pathol2001,195,2:1
11Low - molecular weight heparin in patients with recurrent early miscarriages of unknown aetiology 显示文摘Badawy AM Khiary M Sherif LS 2008J Obstet Gynaecol2008,28,:1
12Determination of cetifizine dihydrochlorlde, related impurities and preservatives in oral solution and tablet dosage forms using HPLC 显示文摘Jaber AM M Sherife HA M Omaro MM 2004Pharm Biomed Anal2004,36,2:1
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