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| 1 | Ag-specific CD4 T cells promote innate immune responses in liver ischemia reperfusion injury显示文摘Our previous studies have documented the unique enrichment of activated CD4 T cells in the liver.Blocking de novo T cell activation did not interfere with their function in ischemia reperfusion injury(IRI).1 We also demonstrated that the CD154-CD40 pathway,but not IFN-γ,was critical for IRI in the liver.Interestingly,alloimmune-primed hosts had significantly more severe IRI in their own livers,which was mediated mainly by CD4 T cells.2 These data prompted us to propose that pre-existing activated CD4 T cells in a host participate in the liver innate immune response against IRI.However,whether these activated/memory T cells require Ag stimulation to function in liver IRI remains unclear.In this report,we addressed this question by utilizing OT II(RAG−/−)T cell receptor transgenic CD4 T cells in a murine liver IRI model. | Jianhua Rao Feng Cheng Shikun Yang Yuan Zhai Ling Lu | 2019 | Cellular & Molecular Immunology2019，16，1： | 2 |
| 2 | Online measurement of alkalinity in anaerobic co-digestion using linear regression method显示文摘Alkalinity is a reliable indicator of process stability in anaerobic digestion system.Total alkalinity(TA)and partial alkalinity(PA)are usually monitored offline as indicators for the status of anaerobic digestion process.In order to online monitor TA and PA,the linear regression method was used as estimator to predict alkalinity via software sensor method.Parameters,namely,pH,oxidation and reduction potential(ORP),and electrical conductivity(EC),were used as input variables.EC was the most significant parameter with TA and PA.Multiple linear regression(MLR)models and simple linear regression models with EC were constructed to predict TA and PA in anaerobic co-digestion system.On the basis of the evaluation of prediction accuracy,the applications of linear regression models were better for monitoring PA than TA.MLR models provided higher accuracy for alkalinity prediction than simple linear regression models.The two MLR models based on single-phase anaerobic digestion system were also feasible to predict TA in anaerobic co-digestion systems.However,the accuracy of these models should be improved by calibrating for broad applications of linear regression method in online alkalinity measurement. | Bai Xue Li Zifu Wang Xuemei He Xi Cheng Shikun Bai Xiaofeng Gao Ruiling | 2017 | International Journal of Agricultural and Biological Engineering2017，10，1： | 1 |
| 3 | Utilization of MSWI fly ash as partial cement or sand substitute with focus on cementing efficiency and health risk assessment显示文摘The strength of cement substituted mortar decreases with the increase in fly ash amount,whereas the strength increases when the fly ash is blended as sand substitute.A mortar with highest strength(compressive strength=30.2 Mpa;flexural strength=7.0 Mpa)was obtained when the sand replacement ratio was 0.75%.The k value(cementing efficiency)of fly ash varied between 0.36 and 0.15 for the fly ash fraction in binder between 5%and 25%.The k values of fly ash used for sand replacement were all significantly above that used for cement substitution.The macropores assigned to the gaps between particles decreased when the fly ash was used as sand replacement,providing an explanation for the strength enhancement.The waste-extraction procedure(toxicity-sulphuric acid and nitric acid method(HJ/T 299-2007))was used to evaluate metal leaching,indicating the reuse possibility of fly ash blended mortar.For the mortar with the mass ratio of fly ash to binder of 0.5%,the carcinogenic risks(CR)and non-carcinogenic hazard quotient(HQ)in sensitive scenario for blended mortar utilization were 9.66 x 10 and 0.06,respectively;these results were both lower than the threshold values,showing an acceptable health risk.The CR(9.89 x 105)and HQ(3.89)of the nonsensitive scenario for fly ash treatment exceeded the acceptable threshold values,indicating health risks to onsite workers.The main contributor to the carcinogenic and non-carcinogenic risk is Cr and Cd,respectively.The CR and HQ from inhalation was the main route of heavy metal exposure. | Lei Zheng Xingbao Gao Wei Wang Zifu Li Lingling Zhang Shikun Cheng | 2020 | Frontiers of Environmental Science & Engineering2020，14，1： | 0 |
| 4 | Research progress of siloxane removal from biogas显示文摘Siloxanes in biogas are detrimental to engine,turbine,fuel cell,etc.,thus it is necessary to remove siloxanes from biogas before biogas high-value utilization.At present,there are few domestic researches and related reports in view of siloxanes removal from biogas.This paper introduces the property of siloxanes as well as sampling and analysis method,and then presents the research progress of siloxanes removal from biogas.Three commercial technologies overseas are adsorption,absorption and cryogenic condensation.Among them,adsorption on activated carbon is the most widely used method.Other technologies,such as biological removal,catalytic processes,membranes,source controlling,etc.are under exploration and development.At last,this paper summarizes the advantages and disadvantages of siloxanes removal technologies as well as the applicability and analyzes the future research trend and emphasis.This paper could provide a reference in the field of biogas high-value utilization. | Gao Ruiling Cheng Shikun Li Zifu | 2017 | International Journal of Agricultural and Biological Engineering2017，10，1： | 0 |
| 5 | Assessment of two faecal sludge treatment plants in urban areas:Case study in Beijing显示文摘Every day,human beings produce excreta all over the world,and the sludge that accumulates in waste disposal systems is referred to as the‘faecal sludge(FS)’.FS can cause serious environmental pollution in urban areas if it cannot be disposed of properly.A complete FS management system must include onsite sanitation technologies,FS collection and transport,a treatment plant,and resource recovery or disposal of the treatment end-products.Focusing on the treatment and reuse/disposal step of a FS complete service chain,this research presents two cases of FS treatment in Beijing.In Case 1,FS biogas plant adopts anaerobic digestion(AD)to treat FS,and the digestate can be used as biofertilizer in the surrounding greenhouse.In Case 2,several technologies including solid-liquid separation,dewatering,pyrolysis,AD and co-composting are integrated to find innovative solutions for FS treatment.A comprehensive assessment including the aspects of technology,economy and environment is conducted for further SWOT(Strengths,Weaknesses,Opportunities and Threats)analysis.Then,critical strategies are developed,which include(1)selecting project site for optimized transportation,maximum waste reuse,minimum environmental impact and convenient final effluent disposal;(2)planning technical options at a feasible study stage,considering resource recovery,secondary pollution prevention and fire protection;(3)exploring market channels for by-products sale to increase profitability;(4)guaranteeing engineering quality and service life for the purpose of sustainable operation;(5)minimizing health risks to persons exposed to the untreated FS;and(6)providing necessary training for hygiene protection.The cases in Beijing can provide valuable lessons for urban areas in developing countries and the strategies can provide a reference for stakeholders and decision-makers who intend to develop FS treatment projects. | Cheng Shikun Zheng Lei Zhao Mingyue Bai Xue Li Zifu Heinz-Peter Mang | 2017 | International Journal of Agricultural and Biological Engineering2017，10，3： | 0 |
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