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您的检索式：作者名="Shiming Duan"
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| 1 | Predicting wall drag coefficient and settling velocity of particle in parallel plates filled with Newtonian fluids显示文摘The hindrance of boundary to particle transport exists widely in various industrial applications.In this study,the wall drag force of parallel plates on settling particles was revealed through settling experiment.High-speed camera was used to record and analyze the settling process of particles in parallel plates that are filled with Newtonian fluids.A total of 600 experiments were carried out,involving the range of relative diameter and particle Reynolds number of 0.01-0.95 and 0.004-14.30,respectively.The wall drag coefficient was defined to quantitatively analyze the wall drag force of the parallel plates.The influence of relative diameter,particle properties,rheological properties,and the settling dynamic process on the wall drag coefficient was revealed,and the wall drag coefficient model with mean relative error of 5.90% was established.Furthermore,an explicit settling velocity model with mean relative error of 8.96% for the particle in parallel plates was developed by introducing a dimensionless variable independent of settling velocity,the Archimedes number.Finally,a calculation example was provided to clarify the using process of the explicit model.This research is expected to provide guidance for optimizing water hydraulic fracturing in the oil and gas industry. | Zhaopeng Zhu Xianzhi Song Gensheng Li Zhengming Xu Silin Jing Xiaozhou Qin Shiming Duan | 2021 | Particuology2021，19，5： | 0 |
| 2 | Effects of intracerebroventricular NMDA and non-NMDA receptor agonists or antagonists on general anesthesia of propofol in mice显示文摘The effects of intracerebroventricular(icv)agonists and antagonists of N-methyl-D-aspartate(NMDA)and alpha-amino-3-hydroxy–5-methyl-4-isoxazole-propionic acid(AMPA)receptors on the general anesthesia of propofol were studied.A total of 144 Kunming mice,male and female with body mass of(22P3)g,were used.Part One of the Experiment:a total of 104 Kunming mice,male and female,were randomly divided into 13 groups.Intracerebroventricular artificial cerebral fluid(aCSF)or different doses of NMDA,AMPA,MK-801 or NBQX was injected immediately after intravenously administered propofol 25 mg/kg and the recovery time following the loss of righting reflex(LORR)was recorded.Part Two of the Experiment:a total of 40 Kunming female mice were divided randomly into 5 groups and injected with icv aCSF or NMDA,AMPA,MK-801 or NBQX after intraperitoneally administered propofol 50 mg/kg.The pain threshold of the mice was then investigated by hot-plate test(HPPT).NMDA(0.05 or 0.075μg,icv)or AMPA(0.05μg,icv)exhibited no effects on the LORR,but NMDA(0.1μg,icv)or AMPA(0.075 or 0.1μg,icv)prolonged the LORR significantly compared with the aCSF group(P<0.05,P<0.01).The LORR of the 2μg MK-801 group had no changes,while those of the 4 or 8μg MK-801 groups were prolonged significantly.The LORR of the 0.5,2 or 4μg NBQX groups were all prolonged significantly.NMDA 0.05μg or AMPA 0.05μg decreased the pain threshold slightly but did not differ in effect compared with the aCSF group;2μg MK-801 or 0.5μg NBQX both increased the pain threshold significantly.Our results indicate that propofol produces general anesthesia partly through an interaction with brain NMDA and AMPA receptors in mice. | XU Aijun DUAN Shiming TIAN Yuke | 2007 | Frontiers of Medicine2007，1，2： | 0 |
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