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| 1 | Current status of intravenous tissue plasminogen activator dosage for acute ischaemic stroke:an updated systematic review显示文摘The optimal dose of recombinant tissue plasminogen activator(rtPA)for acute ischaemic stroke(AIS)remains controversial,especially in Asian countries.We aimed to update the evidence regarding the use of low-dose versus standard-dose rtPA.We performed a systematic literature search across MEDLINE,Embase,Cochrane Central Register of Controlled Trials(CENTRAL),PsycINFO and Cumulative Index to Nursing and Allied Health Literature(CINAHL)from inception to 22 August 2016 to identify all related studies.The outcomes were death or disability(defined by modified Rankin Scale 2-6),death,and symptomatic intracerebral haemorrhage(sICH).Where possible,data were pooled for meta-analysis with ORs and corresponding 95% CIs by means of random-effects or fixed-effects meta-analysis.We included 26 observational studies and 1 randomised controlled trial with a total of 23210 patients.Variable doses of rtPA were used for thrombolysis of AIS in Asia.Meta-analysis shows that low-dose rtPA was not associated with increased risk of death or disability(OR 1.13,95% CI 0.95 to 1.33),or death(OR 0.86,95% CI 0.74 to 1.01),or decreased risk of sICH(OR 1.06,95% CI 0.65 to 1.72).The results remained consistent when sensitivity analyses were performed including only low-dose and standard-dose rtPA or only Asian studies.Our review shows small difference between the outcomes or the risk profile in the studies using low-dose and/or standard-dose rtPA for AIS.Low-dose rtPA was not associated with lower risk of death or disability,death alone,or sICH. | Xia Wang Shoujiang You Shoichiro Sato Jie Yang Cheryl Carcel Danni Zheng Sohei Yoshimura Craig S Anderson Else Charlotte Sandset Thompson Robinson John Chalmers Vijay K Sharma | 2018 | Stroke & Vascular Neurology2018，3，1： | 10 |
| 2 | Cathode properties of phospho-olivine LiMPO4 for lithium secondary batteries显示文摘 | SHIGETO O SHOICHIRO S MINATO E | 2001 | J Power Sources2001，9798，： | 1 |
| 3 | Sex i- dentification of pigs using polymerase chain reaction am- plification of the amelogenin gene显示文摘 | Shoichiro S Shun- ichi S Dai -ichiro F | 2008 | J Zygote2008，16，11： | 1 |
| 4 | A prospective study of the significance of the gene and chromosome alteration as prognostic indicators of breast cancer patients with lymphnode metastases显示文摘 | Hitoshi T Chinami S Shoichiro T | 1998 | Breast cancer Res Treat1998，48，1： | 1 |
| 5 | An adult bimaxillary protrusion treated with corticotomy-facilitated orthodontics and titanium miniplates显示文摘 | Shoichiro L Sumio S Shouichi M | 2006 | Angle Orthod2006，76，6： | 1 |
| 6 | A prospective study of the significance of the gene and chromosome alteration as prognostic indicators of breast cancer patients with lymph node metastases显示文摘 | Chinami S Shoichiro T | 1998 | Breast Cancer Res Treat1998，48，1： | 1 |
| 7 | A Prospective study of the significance of the gene and chromosome alteration as prognostic indicators of breast cancer patients with lymph node metastases显示文摘 | HITOSHI T CHINAMI S SHOICHIRO T | 1998 | Breast Cancer Res Treat1998，48，1： | 1 |
| 8 | Cathode properties of phospho-olivine LiMPO4 for lithium secondary batteries显示文摘 | Shigeto O Shoichiro S Monato E | 2001 | Journal of Power Sources2001，9798，： | 1 |
| 9 | Cathode properties of phospho-olivine LiMPO4 for lithium secondary batteries 显示文摘 | SHIGETO O SHOICHIRO S MINATO E | 2001 | J Power Sources2001，9798，： | 1 |
| 10 | Optimization of seed-blanket type fuel assembly for reduced-moderation water reactor显示文摘 | AFROZA S SHOICHIRO S TERUHIKO K | 2003 | Nuclear Engineering and Design2003，224，： | 1 |
| 11 | A prospective study of the significance of the gene and chromosomal alteration as prognostic indicators of breast cancer patients with lymph node metastasis 显示文摘 | Hitoshi T Chinami S Shoichiro T | 1998 | Breast Cancer Res Treat1998，48，1： | 1 |
| 12 | Endogenous decoy receptor 3 bolcks the groth inhibition signals mediated by Fas ligand in human pancreatic adenocarcinoma显示文摘 | Shoichiro Tsuji Hosotani R Yonehara S | 2003 | Int J Cancer2003，106，： | 1 |
| 13 | High thermal stable thermoplastic-thermosetting polyimide film by use of asymmetric dianhydride(a-BPDA) 显示文摘 | Takeshi S Hiroyuki M Shoichiro Y | 2005 | Polymer2005，46，18： | 1 |
| 14 | Cathode properties of phospho-olivine LiMPO4 for lithium secondary batteries显示文摘 | Shigeto O Shoichiro S Monato E | 2001 | Journal of Power Sources2001，9798，： | 1 |
| 15 | Cathode properties of phosphor - olivine LiMPO4 for lithium secondary batteries 显示文摘 | Shigeto O Shoichiro S Minato E | 2001 | J Power Sources2001，9798，： | 1 |
| 16 | An aduh bimaxillary protru- sion treated with corticotomy-faccilitated orthodontics and titanium miniplates 显示文摘 | Shoichiro L Sumio S Shouiehi M | 2006 | Angel Orthod2006，76，6： | 1 |
| 17 | Spalling test methods for graphite containing nozzles 显示文摘 | Shoichiro F Hiroshi S Toshiaki K | 1983 | Taikabutsu Overseas1983，3，3： | 1 |
| 18 | Effect of carotid endarterectomy on chronic ocular ischemic syndrome due to internal carotid artery stenosis 显示文摘 | Shoichiro K Shuzo O Toshisuke S | 2001 | Neurosurgery2001，48，5： | 1 |
| 19 | Aprospective study of the significance of the gene and chromosome alteration as prog- nostic in dicators of breast cancer patients with lymphnode me- tastases显示文摘 | Hitoshi T Chinami S Shoichiro T | 1998 | Breast Cancer Res Treat1998，48，1： | 1 |
| 20 | A prospective study of the significance of the gene and chromosome alteration as prog- nostic indicators of breast cancer patients with lymphnode metas- tases显示文摘 | Hitoshi T Chinami S Shoichiro T | 1998 | Breast Cancer Res Treat1998，48，1： | 1 |
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