2篇
您的检索式：作者名="Shoukui He"
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| 1 | Cross-protective effect of acid adaptation on ethanol tolerance in Salmonella Enteritidis显示文摘Cross protection can undermine the effectiveness of control measures on foodborne pathogens,and therefore brings major implications for food safety.In this work,the capacity of Salmonella Enteritidis to mount ethanol tolerance following acid adaptation was characterized by analysis of cell viability and cell membrane property.It was observed that preadaptation to pH 4.5 significantly(P<0.05)increased the tolerance of log-phase cells to ethanol;in contrast,stationary-phase cells displayed reduced ethanol tolerance after acid adaptation.However,acid adaptation did not cause cell leakage and morphological change in both log-phase and stationary-phase S.Enteritidis.Fatty acid analysis further revealed that the amount of C_(14:0),C_(17:0 cyclo) and C_(19:0 cyclo) fatty acids was increased,while that of C_(16:1ω7c) and C_(18:1ω7c) fatty acids was decreased,respectively,in response to acid adaptation,regardless of bacterial growth phase.Notably,acid adaptation significantly(P<0.05)increased the proportion of C_(16:0) fatty acid in log-phase cells,but this effect did not occur in stationary-phase cells.Moreover,exogenous addition of C_(16:0) fatty acid to stationary-phase acid-adapted cultures was able to enhance bacterial ethanol tolerance.Taken together,C_(16:0) fatty acid is involved in the growth-phase-dependent protective effect of acid adaptation on ethanol tolerance in S.Enteritidis. | Shoukui He Beining Ye Zengfeng Zhang Yan Cui Siyun Wang Xianming Shi | 2023 | Food Science and Human Wellness2023，12，4： | 0 |
| 2 | Association of SOST gene polymorphisms with peak bone mineral density in Chinese nuclear families with male-offspring显示文摘Peak bone mineral density(BMD)achieved during early adulthood is a highly heritable trait and a strong determinant of subsequent osteoporotic fracture risk.Evidence has already suggested that 50–80% of the variance in peak BMD is genetically determined [1].Human SOST gene comprises three exons and two introns,mapping to chromosomal region 17q12–q21.It inhibits osteoblastic bone formation by inhibiting the Wnt signaling pathway,which is critically important for the development and function of osteoblasts [2].Our previous study in large samples of postmenopausal Chinese women showed that the polymorphisms in the SOST gene are associated with BMD of the lumbar spine [3],but little is known in men.Thus,the objective of this study was to investigate whether polymorphisms in the SOST gene are associated with variations of peak BMD in Chinese nuclear families with male-offspring. | Luyue Qi Shoukui Xiang Li Li Jinwei He Wenzhen Fu Yujuan Liu Yunqiu Hu Zhenlin Zhang | 2019 | Acta Biochimica et Biophysica Sinica2019，51，3： | 0 |
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