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59篇 您的检索式:作者名="Showe M"
    题名 作者 年代 出处 被引量
1The relationship between affect expression and affect recognition in shchizophrenia显示文摘Show RJ Dong M Urn KO 1999Schizophrenia Research1999,37,:1
2显示文摘Show Y Matsuoka F Hayashi M 1998Appl Phys1998,84,:1
3Hypokalemia in Chinese peritoneal diaysis patients:prevalence and prognostic implication 显示文摘Szeto C C Show K M Kwan B C 2005Am J Kidney Dis2005,46,1:1
4Indolopyrido quinazoline al- kaloids with antiplatelet aggregation activity from zanthoxlum in- tergrifoliolum 显示文摘Show W S Tsai IL Teng C M 1996Phytochemistr1996,62,2:1
5The Geological Implication of Steady- State Meehanisms in Catastrophe Theory 显示文摘John M Cubitt Brian show 1976Mathematical Geology1976,8,6:1
6Electrochemical performance of diamond thin-film electrodes from different commercial sources 显示文摘FISHER A E SHOW Y SWAIN G M 2004Anal Chem2004,76,:1
7Thiopurine use associated with reduced B and natural killer cells in inflammatory bowel disease显示文摘AIM To identify which blood and mucosal lymphocyte populations are specifically depleted by thiopurine use in vivo.METHODS The thiopurines azathioprine and 6-mercaptopurine have been a mainstay of inflammatory bowel disease(IBD) therapy for decades, but their mechanism of action in vivo remains obscure. Although thiopurines are lymphotoxic at high doses, and have been reported to cause T cell apoptosis in vitro, their ability to control IBD at lower doses suggests that they may selectively deplete particular lymphocyte populations. Blood cells from 19 IBD patients on a thiopurine, 19 IBD patients not on a thiopurine, and 38 matched healthy control subjects were analyzed by multiple multi-color flow cytometry panels to quantify the immune cell subsets contained therein, both as a percent of cells, and as an absolute cell count. Similar analyses were performed on colon biopsies from 17 IBD patients on a thiopurine, 17 IBD patients not on a thiopurine, and 49 healthy screening colonoscopy recipients.RESULTS Complete blood counts revealed lower lymphocyte, but not monocyte or granulocyte, counts in IBD patients who were taking thiopurines at the timeof sampling. This reduction was restricted to CD3-negative lymphocytes, wherein both natural killer(NK) and B cells were significantly reduced among thiopurine recipients. Among CD19+ B cells, the transitional B cells were particularly depleted, being nearly absent in both blood and colon biopsies of thiopurine recipients. No differences were associated with thiopurine use in CD8+ T cells, mucosa-associated invariant T(MAIT) cells, invariant natural killer T(i NKT) cells, gamma/delta T cells, Th1, Th17, regulatory T cells(Tregs) or na?ve CD4+ T cells. However, patients with IBD had significantly more circulating FOXP3+, Helios+ Tregs and fewer iN KT and MAIT cells than healthy controls. CONCLUSION Thiopurine use is associated with reduced B and NK cell, but not T cell, subpopulations in the blood of IBD patients.James D Lord Donna M Shows 2017World Journal of Gastroenterology2017,23,18:1
8A study of microRNAs insilico and in vivo:bioinformatics approaches to microRNAdiscovery and target identification显示文摘Yousef M Showe L Showe M 2009FEBS J2009,276,8:1
9He-parin and heparan sulfate bind interleukin-10 and modulate its activity 显示文摘ARRAND J R SHOW D MACKETT M 2000Blood2000,96,5:1
10Predicting the depth of insertion of left - sided double - lumen endobronehial - tubes显示文摘Show M Y Gob M H Ti L K 2002Cardiothorac Vasc Anesth2002,16,2:1
11E arly growth response-1 regulates lipopolysaccharide-induced suppressor of cytokine signaling-1 transcription显示文摘M osteck i J Show alter BM Rothm an PB 2005J B iol Chom2005,280,:1
12Increased in output power from fuel cell used metal bipolar plate coated with a-C film 显示文摘Show Y Miki M Nakamura T 2007Diamond Relat Mater2007,16,47:1
13IFN-γ mediated a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression显示文摘SEDGER L M SHOWS D M BLANTON R A 1999J Immunol1999,163,2:1
14An evidence-based appraisal of retlux disease management-The Genval Workshop Report显示文摘Dent J Fendrick AM Fennerty MB Janssens J Kahrilas PJ Lauristen K Reynolds JC Show M Tally NJ 1999Gut1999,44,12:1
15Increased metallothionein gene expression,zinc,and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia显示文摘Raymond A D Gekonge B Giri M S Hancock A Papasavvas E Chehimi J Kossenkov A V Nicols C YousefM Mounzer K Shull J Kostman J Showe L Montaner L J 0,,03:1
16Cloning and structural characterization of a human non-erytheroid band 3-like protein显示文摘Denuth DR Showe IC Ballantle M 1986EMBO J1986,5,:1
17Form- determining function of the genes required for the assembly of the head of bacteriophage T4显示文摘Laemmli U K Molbert E Showe M 0,,01:1
18Influence of width of fertilized band of soil burley tobacco to nitrogen and phosphorus 显示文摘Whitty B E McCants M Show L 1966Tobacco Science1966,,10:1
19Shock State from Initially Liquid Oxygen-Nitrogen System显示文摘Scholl G L Show M S Johnson J D 1985J Chem Phys1985,82,9:1
20Influence of width of fertilized band of soil burley tobacco to nitrogen and phosphorus 显示文摘WhittY B E McCants M Show L 1966Tobacco Science1966,,10:1
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