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| 1 | Long-Term Oral Treatment with Nicorandil Prevents the Progression of Left Ventricular Hypertrophy and Preserves Viability显示文摘 | Simon Schalla Charles B Higgins Maythem Saeed | 2005 | Journal of Cardiovascular Pharmacology2005，，4： | 2 |
| 2 | Quantifying heterogeneity in a Meta-analysis显示文摘 | JULIAN P T Higgins THOMPSON Simon G | 2002 | Statistics in Mdieine Med2002，21，： | 1 |
| 3 | A small mole- cule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage显示文摘 | Simone TM Higgins SP Archambeault J | 2015 | Cell Signal2015，27，5： | 1 |
| 4 | Epidemiology and 12-Month Outcomes From Traumatic Brain Injury in Australia and New Zealand显示文摘 | John A. Myburgh D James Cooper Simon R. Finfer Balasubramanian Venkatesh Daryl Jones Alisa Higgins Nicole Bishop Tracey Higlett | 2008 | The Journal of Trauma: Injury, Infection, and Critical Care2008，，： | 1 |
| 5 | An ellipsometric study of polypyrrole films on platinum显示文摘 | Andrew Hamnett Simon J Higgins Peter R Fisk | 1989 | Journal of Electroanalytical Chemistry1989，270，12： | 1 |
| 6 | Chemical an- tagonists of plasminogen activator inhibitor-1 : mechanisms of action and therapeutic potential in vascular disease显示文摘 | Simone TM Higgins SP Higgins CE | 2014 | J Mol Genet Med2014，8，： | 1 |
| 7 | Antithetie fault linkages in a deep water fold and thrust belt 显示文摘 | Simon Higgins Richard J Davies Benjamin Clarke | 2007 | Journal of Structural Geology2007，29，： | 1 |
| 8 | 吡嗪酰胺对人体单核细胞培养分化的巨噬细胞内的结核分支杆菌无抗菌作用显示文摘地点:克罗拉多州,丹佛,国家犹太人医学和研究中心微生物学实验室。 目的:评价吡嗪酰胺对人体单核细胞培养分化的正常和激活的巨噬细胞中结核分支杆菌的抗菌作用。 设计:将人体血中分离的单核细胞在塑料平皿中培养7天使其衍化成巨噬细胞单层。使用TNF-α或IFN-γ激活或未经过处理的巨噬细胞感染结核分支杆菌。次日加入不同浓度的吡嗪酰胺(PZA)、吗啉酰胺(MZA)或异烟肼(INH),并于第0、4、8天记数细胞内的活菌数。 结果:不论其浓度大小均未发现吡嗪酰胺的抑菌作用,而在同一实验模型中则观察到了随着MZA和异烟肼剂量增加其抑菌和杀菌作用也增加。 结论:PZA对人体单核细胞培养分化的巨噬细胞内滞留或繁殖的结核分支杆菌既无抑菌作用又无杀菌作用,关于人们所知道的该药对结核病人的效力可能与所推测的该药对细胞内菌群的抗菌作用无关。 | L Heifets M. Higgins B. Simon 贺晓新 | 2001 | 国际结核病与肺部疾病杂志2001，，3： | 0 |
| 9 | Short Sleep Duration is Associated with Central Arterial Stiffness in Children Independent of Other Lifestyle Behaviors显示文摘Purpose Children require 9-11 h sleep to ensure adequate growth and development by optimizing the efficiency of a number of biological systems,including the cardiovascular system.The study aim was to determine whether short sleep duration(<9 h)is associated with elevated aortic arterial stiffness in children aged 9-11 years,independent of other lifestyle behav-iors,including physical activity,sedentary behaviour and dietary patterns.Methods This cross-sectional study included 421 children(51%female)aged 9-11 years.Aortic arterial stiffness was measured using carotid-femoral pulse wave velocity(cfPWV),sleep duration,time spent sedentary,and moderate-vigorous physical activity were measured using wrist actigraphy,and dietary patterns using a food frequency questionnaire.Associa-tions between short sleep duration and cfPWV were examined using mixed effects regression.Results There was a positive[unadjusted]association between short sleep duration and cfPWV(β=0.245,95%CI 0.093-0.396).This association persisted following adjustment for demographic factors and was strengthened following adjustment for lifestyle behaviors(β=0.331,95%CI 0.109-0.553).Conclusions Short sleepers(<9 h)had a clinically meaningful elevated aortic arterial stiffness in comparison to those sleeping the recommended daily 9-11 h.Sleep duration may be important for cardiovascular health independent of other lifestyle behaviors. | Lee Stoner Simon Higgins Katherine Black Kim Boggess Michelle L.Meyer Andrea Chou Barbara Galland Jillian J.Haszard Kim Meredith-Jones Pouya Saeedi Sheila Skeaff Paula M.L.Skidmore | 2020 | Journal of Science in Sport and Exercise2020，2，3： | 0 |
| 10 | AB053.Oscillatory activity specific to peripheral emotional treatment induced by a visual steady state显示文摘Background:Research suggests that the analysis of facial expressions by a healthy brain would take place approximately 170 ms after the presentation of a facial expression in the superior temporal sulcus and the fusiform gyrus,mostly in the right hemisphere.Some researchers argue that a fast pathway through the amygdala would allow automatic and early emotional treatment around 90 ms after stimulation.This treatment would be done subconsciously,even before this stimulus is perceived and could be approximated by presenting the stimuli quickly on the periphery of the fovea.The present study aimed to identify the neural correlates of a peripheral and simultaneous presentation of emotional expressions through a frequency tagging paradigm.Methods:The presentation of emotional facial expressions at a specific frequency induces in the visual cortex a stable and precise response to the presentation frequency[i.e.,a steady-state visual evoked potential(ssVEP)]that can be used as a frequency tag(i.e.,a frequency-tag to follow the cortical treatment of this stimulus.Here,the use of different specific stimulation frequencies allowed us to label the different facial expressions presented simultaneously and to obtain a reliable cortical response being associated with(I)each of the emotions and(II)the different times of presentations repeated(1/0.170 ms=~5.8 Hz,1/0.090 ms=~10.8 Hz).To identify the regions involved in emotional discrimination,we subtracted the brain activity induced by the rapid presentation of six emotional expressions of the activity induced by the presentation of the same emotion(reduced by neural adaptation).The results were compared to the hemisphere in which attention was sought,emotion and frequency of stimulation.Results:The signal-to-noise ratio of the cerebral oscillations referring to the treatment of the expression of fear was stronger in the regions specific to the emotional treatment when they were presented in the subjects peripheral vision,unbeknownst to them.In addition,the peripheral emotional treatment of fear at 10.8 Hz was associated with greater activation within the Gamma 1 and 2 frequency bands in the expected regions(frontotemporal and T6),as well as desynchronization in the Alpha frequency bands for the temporal regions.This modulation of the spectral power is independent of the attentional request.Conclusions:These results suggest that the emotional stimulation of fear presented in the peripheral vision and outside the attentional framework elicit an increase in brain activity,especially in the temporal lobe.The localization of this activity as well as the optimal stimulation frequency found for this facial expression suggests that it is treated by the fast pathway of the magnocellular layers. | Caroline Grand-Maître Vanessa Hadid Michèle W.MacLean Marie-Charlotte Higgins Simon Faghel Soubeyrand Franco Lepore | 2018 | Annals of Eye Science2018，，1： | 0 |
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