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| 1 | Efficacy and safety of tenofovir disoproxil fumarate in pregnancy for the prevention of vertical transmission of HBV infection显示文摘AIM:To evaluate the effects of tenofovir disoproxil fumarate(TDF)use during late pregnancy to reduce hepatitis B virus(HBV)transmission in highly viremic mothers.METHODS:This retrospective study included 45 pregnant patients with hepatitis B e antigen(+)chronic hepatitis B and HBV DNA levels>107copies/mL who received TDF 300 mg/d from week 18 to 27 of gestation(n=21).Untreated pregnant patients served as controls(n =24).All infants received 200 IU of hepatitis B immune globulin(HBIG)within 24 h postpartum and 20μg of recombinant HBV vaccine at 4,8,and 24 wk.Perinatal transmission rate was determined by hepatitis B surface antigen and HBV DNA results in infants at week 28.RESULTS:At week 28,none of the infants of TDFtreated mothers had immunoprophylaxis failure,whereas2(8.3%)of the infants of control mothers had immunoprophylaxis failure(P=0.022).There were no differences between the groups in terms of adverse events in mothers or congenital deformities,gestational age,height,or weight in infants.At postpartum week 28,significantly more TDF-treated mothers had levels of HBV DNA<250 copies/mL and normalized alanine aminotransferase compared with controls(62%vs none,P<0.001;82%vs 61%,P=0.012,respectively).CONCLUSION:TDF therapy during the second or third trimester reduced perinatal transmission rates of HBV and no adverse events were observed in mothers or infants. | Mustafa Kemal Celen Duygu Mert Müzeyyen Ay Tuba Dal Safak Kaya Necmettin Yildirim Serda Gulsun Tunga Barcin Sevgi Kalkanli Mehmet Sinan Dal Celal Ayaz | 2013 | World Journal of Gastroenterology2013，19，48： | 26 |
| 2 | Percutaneous coblation nucleoplasty in patients with contained lumbar disc pro- lapse: 1 year follow-up in a prospective case series 显示文摘 | Sinan T Sheikh M Burie J | 2011 | Acta Neurochir Suppl2011，108，： | 1 |
| 3 | Percutaneous coblation nucleoplasty in patients with contained lumbar disc prolapse: 1 year follow-up in a prospective case series显示文摘 | Sinan T Sheikh M Buric J | 2011 | Acta Neurochir Suppl2011，108，： | 1 |
| 4 | Determination of efficiency of flat-plate solar collectors using neural network approach 显示文摘 | ADNAN S TAYFUN M SINAN U | 2008 | Expert Systems with Applications2008，35，4： | 1 |
| 5 | CT features in abdominal tuberculosis: 20 years experience显示文摘 | Sinan T Sheikh M Ramadan S | 2002 | BMC Med Imaging2002，2，1： | 1 |
| 6 | Giant cell tumor of the temporal bone:case report and review of the literature显示文摘 | Sheilch M Chisti FA Sinan T | 1999 | Australasian Radiology1999，43，： | 1 |
| 7 | On baseline corrections and uncertainty in response spectra for baseline variations commonly encountered in digital accelerograph records显示文摘 | Sinan Akkar and David M Boore | 2009 | Bulletin of the Seismological Society of America2009，99，3： | 1 |
| 8 | CT features in abdominal tubereulosis : 20 years experience 显示文摘 | Sinan T Sheikh M Ramadan S | 2002 | BMC Med Imaging2002，2，1： | 1 |
| 9 | COD fractions of leachate from aerobic and anaerobic pilot scale landfill reactors显示文摘 | Sinan B M Demir A Ebru A | 2008 | J Hazard Mater2008，158，1： | 1 |
| 10 | Diam device for low back pain in degenerative disc disease:24 months follow-up显示文摘 | Buric J Pulidori M Sinan T | | 0，，： | 1 |
| 11 | CT features in abdominal tuberculosis:20 years experience显示文摘 | Sinan T Sheikh M Ramadan S | 2002 | BMC Med Imaging2002，2，1： | 1 |
| 12 | An Extension to the DRAS- TIC Model to Assess Groundwater Vulnerability to Pollution : Application to the Haouz Aquifer of Marra- kech ( Morocco ) 显示文摘 | SINAN M RAZACK M | 2009 | Environmental Geology2009，57，2： | 1 |
| 13 | Spinal tuberculosis: CT and MRI features显示文摘 | Sinan T AL-khawari H Ismail M | 2004 | Ann Saudi Med2004，24，6： | 1 |
| 14 | Distributed mobile sink routing for wireless sensor networks:A survey显示文摘 | Tunca Can Sinan Isik Donmez M Yunus | 2014 | IEEE Communications Surveys&Tutorials2014，16，： | 1 |
| 15 | CT Features in Ab- dominal Tuberculosis : 20 Years Experience 显示文摘 | Sinan T Sheikh M Ramadan S | 2002 | BMC Med Imaging2002，2，1： | 1 |
| 16 | Spinal tuberculosis: CT and MRI feature 显示文摘 | Sinan T A1-Khawari H Ismail M | 2004 | Ann Saudi Med2004，24，6： | 1 |
| 17 | Adsorption of 4-chlorophenol from aqueous solutions by xad-4 resin:Isotherm,kinetic and thermodynamic analysis显示文摘 | SINAN BILGILI M | | 0，，01： | 1 |
| 18 | Mechanics of the tapered interference fit in dental implants 显示文摘 | Bozkaya D Sinan M | 2003 | Journal of Biomechanics2003，36，： | 1 |
| 19 | Spinal tuberculosis: CT and MRI feature显示文摘 | Sinan T Al-Khawari H Ismail M | 2004 | Ann Saudi Med2004，24，6： | 1 |
| 20 | CT features in abdominal tuberculosis:20 years experience显示文摘 | Sinan T Sheikh M Ramadan S | 2002 | BMC Med Imaging2002，2，1： | 1 |
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