|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 曲马多治疗糖尿病性神经疼痛的双盲随机试验显示文摘目的 :本研究旨在评价曲马多治疗糖尿病性神经痛的有效性和安全性。背景 :糖尿病性神经痛是糖尿病患者的主要症状 ,其治疗和其他的末梢神经病变一样 ,不能令人满意。曲马多是作用于中枢的镇痛剂 ,用于治疗中到重度疼痛。方法 :多中心、门诊病例、随机、双盲、安慰剂做对照、设置平行组的研究 ,包括清洗期 (在此期间停用所有镇痛剂 )和一个为期 42天的双盲治疗期。总共有 1 31名患糖尿病性神经痛的患者按每日 4次接受了曲马多 (n =65)或看上去与曲马多相同的安慰剂胶囊治疗 (n =66)。 42天的治疗结束后或治疗中断后比较曲马多组和安慰剂组平均疼痛强度评分作出主要有效性分析 ;次要有效性分析为疼痛缓解率评分和根据日常活动和睡眠状况作出的对生活质量的评估。结果 :曲马多平均剂量为 2 1 0mg/天 ,治疗糖尿病性神经痛较安慰剂有显著疗效 (P≤ 0 .0 0 1 )。曲马多组患者生理(P =0 .0 2 )和社会功能 (P =0 .0 4 )的评分显著优于安慰剂组。未发现对睡眠有显著治疗作用。曲马多最常见的不良反应是恶心 ,便秘 ,头疼和嗜睡。结论 | Harati Y Gooch C Swenson M Green D Raskin P Donofrio P Cornblath D Sachdeo R Siu CO Kamin M | 2001 | 中国疼痛医学杂志2001，7，1： | 2 |
| 2 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 3 | Ultra - early surgery for aneurysmal subaraehnoid hemorrhage: outcomes for a consecutive series of 391 patients not selected by grade or age显示文摘 | Laidlaw J D Siu K H | 2002 | J Neurosurg2002，97，： | 1 |
| 4 | Risk and predictors forpregnancy-related complications in women with heart disease 显示文摘 | Siu S C Sermer M Harrison D A | 1997 | Circulation1997，96，9： | 1 |
| 5 | The influence of visual perception of self-motion on locomotor adaptation to unilateral limb loading显示文摘 | Mukherjee M Siu KC Katsavelis D | 2011 | J Mot Behav2011，43，2： | 1 |
| 6 | Nicotine self-administration in mice is associated with rates of nicotine inactivation by CYP2A5显示文摘 | Siu E C Wildenauer D B Tyndale R F | 2006 | Psychopharmacology (Berl)2006，，184： | 1 |
| 7 | Representing Context, Cognition, and Crew Performance in a Shutdown Risk Assessment 显示文摘 | Gertman D I Haney L N Siu N O | 1996 | Reliability Engineering and System Safety1996，52，4： | 1 |
| 8 | DNA binding and cyto- toxicity of ruthenium(II) and rhenium(I) complexes of 2 -Amino-4-phenylamino-6- (2-pyridyl) - 1,3,5 -triazine 显示文摘 | Ma D L Che C M Siu F M | 2007 | Inorg Chem2007，46，： | 1 |
| 9 | The Chinese version of the Social Prob-lem-solving Inventory:some initial results on reliability andvalidity显示文摘 | Siu A M Shek D T | 2005 | J Clin Psychol2005，61，3： | 1 |
| 10 | The anatomy and functional axes of the femur显示文摘 | Yoshioka Y Siu D Cooke TD | 1987 | J Bone Joint Surg Am1987，69，： | 1 |
| 11 | Denoising by Singularity Detection显示文摘 | Hsung T C Lun D P K Siu Wanehi | 1999 | IEEE Transactions on Signal Processing1999，47，11： | 1 |
| 12 | Poor - grade aneurysmal subarachnoid hemor- rhage: outcome after treatment with urgent surgery显示文摘 | Laidlaw J D Siu KH | 2003 | Neurosur- gery2003，53，6： | 1 |
| 13 | A study of family support,friend- ship,and psychological well-being among older women in Hong Kong显示文摘 | Siu O L Phillips D R | 2002 | Int J Aging Hum Dev2002，55，4： | 1 |
| 14 | Denoising by singularity detection显示文摘 | HSUNG T C LUN D P K SIU W C | 1999 | IEEE Transactions on Signal Processing1999，47，11： | 1 |
| 15 | Adhering junction dynamics in the testis are regulated by an interplay of betal- integrin and focal adhesion complex-associated proteins 显示文摘 | Siu M K Mruk D D Lee W M | 2003 | Endocrinology2003，144，5： | 1 |
| 16 | Ion Chromatographic Determination of Nitrate and Nitrite in Meat Products显示文摘 | Siu D C Henshall A Dasgupta P K | 1998 | Journal of Chromatography A1998，804，12： | 1 |
| 17 | The anatomy and functional axes of the femur显示文摘 | Yoshioka Y Siu D Cooke TD | 1987 | J Bone Joint Surg( Am )1987，6，： | 1 |
| 18 | Molecularly targeted oncology therapeutics and prolongation of the QT interval 显示文摘 | Strevel EL Ing D J Siu LL | 2007 | J Clin Oncol2007，25，22： | 1 |
| 19 | Aging influences cellu lar and molecular responses of apoptosis to skeletal muscle unloading显示文摘 | Siu P M Pistiili E E Butler D C et 01 | 2005 | Am J Physiol Cell Physiol2005，288，2： | 1 |
| 20 | Assessing Regional Virtual Water Flows and Water Footprints in the Yellow River Basin, China: A Consumption Based Approach 显示文摘 | Feng K S Siu Y L Guan D B | 2012 | Applied Geography2012，32，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员