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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Cetylpyridinium chloride ( CPC ) treatment on poultry skin to reduce attached Salmonella 显示文摘 | Kim J W Slavik M F | 1996 | Journal of Food Protection1996，59，3： | 1 |
| 3 | Ultrafast alloptical differentiators显示文摘 | Slavik R Park Y Kulishov M Morandotti R Aza(n)ia J | | 0，，22： | 1 |
| 4 | Identification and enumeration of salmonella on sample slides of poultry wash water using image analysis with fluorescent microscopy显示文摘 | Huang J Li Y Slavik M F | 1999 | Transactions of the ASAE1999，42，1： | 1 |
| 5 | Removal of phtbalates from aqueous solution by different adsorbents: a short review 显示文摘 | Julinov M Slavik R | 2012 | Journal of Environmental Management2012，94，1： | 1 |
| 6 | CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28显示文摘 | SLAVIK J M FIUTCHCROFT J E BIERER B E | 1999 | J Biol Chem1999，274，5： | 1 |
| 7 | Paclitaxel (Taxol) : a review of its antitumor activity in clinical studiesMinireview 显示文摘 | Hajek R Vorlicek J Slavik M | 2006 | Neoplasma2006，43，3： | 1 |
| 8 | Isolation, partial purification and characterization of a baeteriocin produced by a newly isolated Bacillus subtilis strain 显示文摘 | Zheng G Slavik M | 1999 | Lett Appl Bacteriol1999，28，5： | 1 |
| 9 | On the convergence of a combined finite volume-finite element methods for nonlinear convection-diffusion problems explicit schemes,numerical method for partioal differential equations显示文摘 | Feistauer M Slavik J Stupka P | 1999 | International Journal For Numerical Methods In Engineering1999，13，2： | 1 |
| 10 | Detection of Campylobacter jejuni in poultry samples using an enzyme-linked immunoassay coupled with an enzyme electrode显示文摘 | Che Y Li Y Slavik M | 2001 | Biosens Bioelectrons2001，16，： | 1 |
| 11 | Paclitaxel (Taxol):a review of its antitumor activity in clinical studies minireview显示文摘 | Hajek R Vorlicek J Slavik M | 1996 | Neoplasma1996，43，3： | 1 |
| 12 | Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with cntinuous 5-fluorouracil infusion显示文摘 | Fabian CJ Molina R Slavik M | 1990 | Invest New Drugs1990，8，： | 1 |
| 13 | 5-Azacytidine(NSC 102816): a new anticancer drug with effectiveness in acute myelogenous leukemia 显示文摘 | Von Hoff DD Slavik M Muggia FM | 1976 | Ann Intern Med1976，85，： | 1 |
| 14 | Isolation,partial purification and characterization of a bacteriocin produced by a newly isolated Bacillus subtilis strain显示文摘 | Zheng G Slavik M F | 1999 | Applied Microbiology1999，28，： | 1 |
| 15 | Pyridoxine therapy for palmarplantar erythrodysesthesia associated with continuous 5-fluorouracil infusion显示文摘 | Fabian C J Molina R Slavik M | 1990 | Invest New Drugs1990，8，： | 1 |
| 16 | Can automatedblood film analysis replace the manual differential?Anevaluation of the CellaVision DM96 automated imageanalysis system显示文摘 | Briggs C Longair I Slavik M | 2009 | Int J Lab Hematol2009，31，1： | 1 |
| 17 | DREZ(dorsal root entry zone)surgery for the treatment of the postherpetic intercostal neuralgia显示文摘 | Spaic M Ivanovic S Slavik E | 2004 | Acta Chir Iugosl2004，51，4： | 1 |
| 18 | Paclitaxel(Taxol):a review of its antitumor activity in clinical studies Minireview显示文摘 | Vorlicek J Slavik M | 1996 | Neoplasma1996，43，3： | 1 |
| 19 | Picosecond and sub-picosecond flat-top pulse generation using uniform long-period fiber gratings 显示文摘 | PARKL Y KULISHOV M SLAVIK R | 2006 | Optics Express2006，14，12： | 1 |
| 20 | Rapid detection of Listeria monocytogenes using quantum dots and nanobeads-based optical biosensor显示文摘 | Wang H Li Y B Slavik M | 2007 | Rapid Methods & Automation in Microbiology2007，15，1： | 1 |
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