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| 1 | Cellular and molecular aspects of gastric cancer显示文摘胃的癌症与变的负担仍然是一个全球杀手从发展了到发展中的世界。癌症沿着被定义由的一个多级式的过程发展不同组织学并且 pathophysiological 阶段。几基因、渐成说的改变调停从一个的转变上演到另外一个,这些在 oncogenes 包括变化,瘤压制或基因和房间骑车并且错配修理基因。在对胃的癌症的战斗的最重要的进展为这癌症作为最重要的获得的病因论的代理人与 Helicobacter pylori (H pylori ) 的角色的识别来了。最近的工作在阐明上集中了位于肿瘤的过程下面的复杂 host/microbial 相互作用。现在进这癌症的致病和阻止并且根除的前景有可观的卓见疾病成为了现实。也许更重要地, H 导致 pylori 的胃的致癌作用的学习为理解更复杂的人的癌症提供一个范例。在这评论,我们检验位于 H 下面的分子、细胞的事件导致 pylori 的胃的癌症。 | Malcolm G Smith Georgina L Hold Eiichi Tahara Emad M El-Omar | 2006 | World Journal of Gastroenterology2006，12，19： | 29 |
| 2 | Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years?显示文摘Our understanding of the microbial involvement in inflammatory bowel disease(IBD) pathogenesis has increased exponentially over the past decade. The development of newer molecular tools for the global assessment of the gut microbiome and the identification of nucleotide-binding oligomerization domain-containing protein 2 in 2001 and other susceptibility genes for Crohn's disease in particular has led to better understanding of the aetiopathogenesis of IBD. The microbial studies have elaborated the normal composition of the gut microbiome and its perturbations in the setting of IBD. This altered microbiome or 'dysbiosis' is a key player in the protracted course of inflammation in IBD. Numerous genome-wide association studies have identified further genes involved in gastrointestinal innate immunity(including polymorphisms in genes involved in autophagy: ATG16L1 and IGRM), which have helped elucidate the relationship of the local innate immunity with the adjacent luminal bacteria. These developments have also spurred the search for specific pathogens which may have a role in the metamorphosis of the gut microbiome from a symbiotic entity to a putative pathogenic one. Here we review advances in our understanding of microbial involvement in IBD pathogenesis over the past 10 years and offer insight into how this will shape our therapeutic management of the disease in the coming years. | Georgina L Hold Megan Smith Charlie Grange Euan Robert Watt Emad M El-Omar Indrani Mukhopadhya | 2014 | World Journal of Gastroenterology2014，20，5： | 21 |
| 3 | 健康领域的文化能力显示文摘1背景
尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。 | Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K | 2016 | 中国卫生政策研究2016，9，2： | 5 |
| 4 | 拼焊板胀形成形不均匀性变形理论分析显示文摘从材料的变形机理出发,针对厚度比不同的拼焊板,通过有限元分析方法对降低成形极限的原因进行了分析和解释,证实焊缝两侧金属的变形条件差异和变形路径是影响整体变形程度的重要因素.并在此基础上,对曲线焊缝拼焊板的厚度比与成形高度之间的关系进行了研究,发现随着厚度的增加,成形高度并不呈递减的趋势,这与直线焊缝情况下是不同的. | 田浩彬 林建平 刘瑞同 Smith L M | 2007 | 同济大学学报(自然科学版)2007，35，1： | 5 |
| 5 | Comparison of parametric and nonparametric models for traffic flow forecasting显示文摘 | Brian L Smith Billy M Williams R Keith Oswald | 2002 | Transportation Research Part C2002，，4： | 3 |
| 6 | The Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) Trial显示文摘 | E Feldmann J L. Wilterdink A Kosinski M Lynn M I. Chimowitz J Sarafin H H. Smith F Nichols J Rogg H J. Cloft L Wechsler J Saver S R. Levine C Tegeler R Adams M Sloan | 2007 | Neurology2007，，24： | 2 |
| 7 | A CMOS based analog standard cell product family 显示文摘 | Smith L D Farmer H R Kunesh M | 1989 | IEEE Journal of Solid-State Circuits1989，24，4： | 2 |
| 8 | 文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响
政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。 | Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K | 2016 | 中国卫生政策研究2016，9，3： | 2 |
| 9 | Genetic influences on beef longissimus palatability in Charolais-and Limousin-sired steers and heifers显示文摘 | Wulf D M Tatum J D Green R D Morgan J B Golden B L and Smith G C | 1996 | J Anim Sci1996，74，： | 2 |
| 10 | CXCR4 regulates growth of both prima ry and metastatic breast cancer显示文摘 | Smith M C Luker K E Garbow J R Prior J L Jackson E Piwnica-Worms D | 2004 | Cancer Res2004，64，： | 1 |
| 11 | Meta - analysis of Research on Class Size and Achievement 显示文摘 | Class G V Smith M L | 1979 | Educational Evaluation and Policy Analysis1979，，1： | 1 |
| 12 | Use of the FAO CROPWAT model in deficit irrigation studies显示文摘 | Smith M Kivumbi D Heng L K | | Defieit Irrigation Practices0，22，： | 1 |
| 13 | Comparison of parametric and nonparametric models for traffic flow forecasting显示文摘 | Smith B L Williams B M Keith Oswald R | 2002 | Transportation Research Part C2002，10，： | 1 |
| 14 | Time-dependent effects of intermittent hydrostatic pressure on aeticular chondrocyte type II collagen and aggrecan mRNA expression显示文摘 | SMITH R L LIN J TRINDADE M C | 2000 | J Reha bil Res Dev2000，37，2： | 1 |
| 15 | Cancer surveillance series: recent trends in childhood cancer incidence and mortality in the United States 显示文摘 | Linet S Ries L A Smith M A | 1999 | J Nad Cancer Inst1999，91，12： | 1 |
| 16 | Comparison of parametric and nonparametric models for traffic flow forecasting 显示文摘 | Smith B L Williams B M Oswald R K | 2002 | Transportation Research Part C : Emerging Technologies2002，10，4： | 1 |
| 17 | Antigenic variants of J subgroup avian leucosis virus: sequence analysis reveals multi- ple changes in env gene 显示文摘 | Venugoal K Smith L M Howes K | 1998 | J Gen Virol1998，79，： | 1 |
| 18 | Comparison of parametric and nonparametric models for traffic flow forecasting显示文摘 | SMITH B L WILLAIMS B M OSWALD R K | 2003 | Transportation Research Part C2003，10，4： | 1 |
| 19 | The air toxics health effects database (ATHED)显示文摘 | WOODALL G M SMITH R L | 2008 | Toxicology and Applied Pharmacology2008，233，： | 1 |
| 20 | A structur- al approach to assessing innovation: construct develop- ment of innovation locus, type and characteristics 显示文摘 | Gatignon H Tushman M L Smith W | 2004 | Management Science2004，48，： | 1 |
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