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您的检索式：作者名="Smriti Gupta"
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| 1 | Molecular and biochemical trajectories from diabetes to Alzheimer's disease: A critical appraisal显示文摘Diabetes mellitus(DM), a metabolic disorder is a major orchestra influencing brain and behavioral responses via direct or indirect mechanisms. Many lines of evidence suggest that diabetic patients apparently face severe brain complications, but the story is far from being fully understood. Type 2 diabetes, an ever increasing epidemic and its chronic brain complications are implicated in the development of Alzheimer's disease(AD). Evidences from clinical and experimental studies suggest that insulin draws a clear trajectory from the peripheral system to the central nervous system. This review is a spot light on striking pathological, bio-chemical, molecular and behavioral commonalities of AD and DM. Incidence of cognitive decline in diabetic patients and diabetic symptoms in AD patients has brought the concept of brain diabetes to attention. Brain diabetes reflects insulin resistant brain state with oxidative stress, cognitive impairment, activation of various inflammatory cascade and mitochondrial vulnerability as a shared footprint of AD and DM. It has become extremely important for the investigators to understand the patho-physiology of brain complications in diabetes and put intensive pursuits for therapeutic interventions. Although, decades of research have yielded a range of molecules with potential beneficial effects, but they are yet to meet the expectations. | Rajat Sandhir Smriti Gupta | 2015 | World Journal of Diabetes2015，6，12： | 8 |
| 2 | A novel class of Helitron- related transposable elements in maize contain portions of multiple pseudogenes显示文摘 | Smriti Gupta Andrea Gallavotti Gabrielle A. Stryker Robert J. Schmidt Shailesh K. Lal | 2005 | Plant Molecular Biology2005，，1： | 1 |
| 3 | Conserving biodiversity through traditional beliefs in sacred groves in Uttarakhand Himalaya, India显示文摘 | Ashish Anthwal Nutan Gupta Archana Sharma Smriti Anthwal KI-Hyun Kim | 2010 | Resources Conservation & Recycling2010，，11： | 1 |
| 4 | Phenomenology,disability and sexual functioning in female Dhat syndrome:a study of tertiary care gynaecology outpatients显示文摘Background Dhat syndrome,a clinical condition related to semen loss in urine often found among males in India,has rarely been described as a separate clinical condition in females.Women with the syndrome complain of passing vaginal discharge and can be excessively concerned and preoccupied with it,often attributing various physical symptoms to the loss of vaginal fluids.Aims This study aimed to assess the sociodemographic and clinical profiles of female patients with Dhat syndrome and their perceived stress,disability and sexual functioning.Methods Sociodemographic details of 70 females with non-pathological vaginal discharge were evaluated with a semistructured sociodemographic assessment.The phenomenology of the vaginal discharge was assessed with the Scale for Assessment of Female Dhat Syndrome Questionnaire.Anxiety and depressive symptoms were measured with the Hospital Anxiety and Depression Scale.Perceived stress in the past month and disability caused by the illness were assessed with the Perceived Stress Scale and the World Health Organization Disability Assessment Scale.In addition,the Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition,Level 2 Somatic Symptoms Scale was administered to rate the severity of somatic symptoms,and sexual functioning was evaluated using the Female Sexual Function Index(FSFI)scale for women who had had sexual intercourse in the past month.Results The mean age of onset vaginal discharge was 23.0(6.6)years.Biological factors,such as urinary tract infection,were the commonly attributed cause of the loss of vaginal fluids.Psychiatric comorbidity and perceived moderate stress in the past month were found in 38.6%and 68.6%of female patients with Dhat syndrome,respectively.Disability scores tended to be low.Among the females having had sexual intercourse in the past month,48.3%had FSFI scores indicative of a female sexual disorder.Conclusions The clinical presentation of women with non-pathological vaginal discharge is similar to that of males with Dhat syndrome.It requires comprehensive assessment and management that targets the biological,social and psychological factors and cultural issues. | Shubha Joshi Adarsh Tripathi Smriti Agarwal Nisha Singh Bandna Gupta Anil Nischal Sujita Kumar Kar | 2022 | General Psychiatry2022，35，5： | 0 |
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