|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Helicobacter pylori and autoimmune disease:Cause or bystander显示文摘Helicobacter pylori(H.pylori)is the main cause of chronic gastritis and a major risk factor for gastric cancer.This pathogen has also been considered a potential trigger of gastric autoimmunity,and in particular of autoimmune gastritis.However,a considerable number of reports have attempted to link H.pylori infection with the development of extra-gastrointestinal autoimmune disorders,affecting organs not immediately relevant to the stomach.This review discusses the current evidence in support or against the role of H.pylori as a potential trigger of autoimmune rheumatic and skin diseases,as well as organ specific autoimmune diseases.We discuss epidemiological,serological,immunological and experimental evidence associating this pathogen with autoimmune diseases.Although over one hundred autoimmune diseases have been investigated in relation to H.pylori,we discuss a select number of papers with a larger literature base,and include Sj grens syndrome,rheumatoid arthritis,systemic lupus erythematosus,vasculitides,autoimmune skin conditions,idiopathic thrombocytopenic purpura,autoimmune thyroid disease,multiple sclerosis,neuromyelitis optica and autoimmune liver diseases.Specific mention is given to those studies reporting an association of anti-H.pylori antibodies with the presence of autoimmune disease-specific clinical parameters,as well as those failing to find such associations.We also provide helpful hints for future research. | Daniel S Smyk Andreas L Koutsoumpas Maria G Myt-ilinaiou Eirini I Rigopoulou Lazaros I Sakkas Dimitrios P Bogdanos | 2014 | World Journal of Gastroenterology2014，20，3： | 12 |
| 2 | Infectome: A platform to trace infectious triggers of autoimmunity显示文摘 | Dimitrios P. Bogdanos Daniel S. Smyk Pietro Invernizzi Eirini I. Rigopoulou Miri Blank Shideh Pouria Yehuda Shoenfeld | 2013 | Autoimmunity Reviews2013，，7： | 2 |
| 3 | Autoanti- bodies in autoimmune pancreatitis 显示文摘 | Smyk DS Rigopoulou EI Koutsoumpas AL | 2012 | Int J Rheumatol2012，2012，94： | 1 |
| 4 | Smoking as a risk factor for autoimmune liver disease :what we can learn from primary biliary cirrho- sis显示文摘 | Smyk DS Rigopoulou El Muratori L | 2012 | Ann Hepatol2012，11，1： | 1 |
| 5 | Steady-state and time-resolved fluorescence studies of stripped borage oil 显示文摘 | Smyk B Amarowicz R Szabelski M | 2009 | Analytica Chimica Acta2009，646，7： | 1 |
| 6 | Tracing envi-ronmental markers of autoimmunity : introducing the in-fection显示文摘 | Bogdanos DP Smyk DS lnvernizzi P | 2013 | Immunol Res2013，56，4： | 1 |
| 7 | Clinical and mo- lecular features of the i mmunodysregulation,polyendocrinopathy,enteropathy,X linked (IPEX) syndrome 显示文摘 | Wildin RS Smyk - Pearson S Filipovich AH | 2002 | Med Genet2002，39，8： | 1 |
| 8 | Sex differences associated with primary biliary cirrhosis 显示文摘 | SMYK D S RIGOPOULOU E I PARES A | 2012 | Clin Dev Immunol2012，2012，61： | 1 |
| 9 | Diagnostic value,clinical utility and pathogenic significance of reactivity to the molecular targets of Crohn' s disease specific-pancreatic autoantibodies显示文摘 | Bogdanos DP Rigopoulou EI Smyk DS | 2011 | Autoimmun Rev2011，11，： | 1 |
| 10 | Role for mycobacterial infection in pathogenesis of primary biliary cirrhosis?显示文摘Primary biliary cirrhosis(PBC) is a progressive cholestatic liver disease characterized by the immunemediated destruction of biliary epithelial cells in small intrahepatic bile ducts.The disease is characterized by circulating antimitochondrial antibodies(AMAs) as well as disease-specific antinuclear antibodies,cholestatic liver function tests,and characteristic histological features,including granulomas.A variety of organisms are involved in granuloma formation,of which mycobacteria are the most commonly associated.This has led to the hypothesis that mycobacteria may be involved in the pathogenesis of PBC,along with other infectious agents.Additionally,AMAs are found in a subgroup of patients with mycobacterial infections,such as leprosy and pulmonary tuberculosis.Antibodies against species-specific mycobacterial proteins have been reported in patients with PBC,but it is not clear whether these antibodies are specific for the disease.In addition,data in support of the involvement of the role of molecular mimicry between mycobacterial and human mitochondrial antigens as triggers of cross-reactive immune responses leading to the loss of immunological tolerance,and the induction of pathological features have been published.Thus,antibodies against mycobacterial heat shock protein appear to cross-recognize AMA-specific autoantigens,but it is not clear whether these autoantibodies are mycobacterium-species-specific,and whether they are pathogenic or incidental.The view that mycobacteria are infectious triggers of PBC is intriguing,but the data provided so far are not conclusive. | Daniel Smyk Eirini I Rigopoulou Yoh Zen Robin Daniel Abeles Charalambos Billinis Albert Pares Dimitrios P Bogdanos | 2012 | World Journal of Gastroenterology2012，18，35： | 1 |
| 11 | Fluorescence study of sinapic acid interaction with bovine serum albumin and egg albumin 显示文摘 | SMYK B | 2003 | Journal of Flurescence2003，13，4： | 1 |
| 12 | Different-sized duplications of Xq28, including MECP2, in three males with mental retardation, absent or delayed speech, and recurrent infections 显示文摘 | Smyk M Obersztyn E Nowakowska B | 2008 | Am J Med Genet B Neuropsychiatr Genet2008，147，6： | 1 |
| 13 | Interrupted Aortic Arch in an Adult Female显示文摘 | Kleinrok A Zaremba-Flis E Smyk T | 2010 | Echocardiography2010，27，7： | 1 |
| 14 | Temporally coherent irradiance caching for high quality animation rendering显示文摘 | Kinuwaki S Smyk M Durikovic R | 2005 | Eurographics Workshop Rendering2005，24，3： | 1 |
| 15 | Diagnostic and clinical significance of Crohn’s disease-specific anti-MZGP2 pancreatic antibodies by a novel ELISA显示文摘 | Polychronis Pavlidis Zakera Shums Andreas L. Koutsoumpas Jay Milo Maria Papp Takeji Uemurea Peter Lakatos Daniel S. Smyk Dimitrios P. Bogdanos Alastair Forbes Gary L. Norman | 2014 | Clinica Chimica Acta2014，，： | 1 |
| 16 | Clinical and molecular fea- tures of the immunodysregulation, polyendocrinopathy, enteropathy, linked IPEX)syndrome显示文摘 | Wildin RS Smyk - Pearson S Filipovich AH | 2002 | J Med Genet2002，39，8： | 1 |
| 17 | Potential Roles for Infectious Agents in the Pathophysiology of Primary Biliary Cirrhosis:What's New?显示文摘 | Smyk DS Rigopoulou EI Bogdanos DP | 2013 | Curr Infect Dis Rep2013，15，： | 1 |
| 18 | Immunopathogenesis of primary biliary cirrhosis:an old wives' tale显示文摘 | Smyk DS Rigopoulou EI Lleo A | | 0，，： | 1 |
| 19 | Recurrent SOX9 deletion campomelic dysplasia due to somatic mosaicism in the father 显示文摘 | Smyk M Obersztyn E Nowakowska B | 2007 | Am J Meal Genet A2007，143，8： | 1 |
| 20 | Urinary tract infection as a risk factor for autoimmune liver disease : from bench to bedside 显示文摘 | Smyk DS Bogdanos DP Kriese S | 2012 | Clin Res Hepatol Gastroenterol2012，36，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员