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| 1 | 年轻绝经前妇女患子宫内膜癌的危险因素 | Soliman P.T. Oh J.C. Schmeler K.M. 张丽娟 | 2005 | 世界核心医学期刊文摘(妇产科学分册)2005，0，7： | 2 |
| 2 | 安德森博士癌症中心完全腹腔镜下广泛子宫根治术及淋巴结切除术经验显示文摘Objective.:To retrospectively evaluate the feasibility and morbidity of total laparoscopic radical hysterectomy and lymphadenectomy. Methods.:We performed a retrospective review of all patients who underwent a total laparoscopic radical hysterectomy at our institution between May 2004 and August 2005. Data collected included age,body mass index,stage,histopathologic subtype,tumor grade,estimated blood loss,perioperative blood transfusions,number and status of lymph nodes obtained,status of surgical margins,length of hospital stay,time to resumption of normal bladder function,intraoperative and postoperative complications,and disease-free interval. Results.:Twenty patients underwent total laparoscopic radical hysterectomy during the study period. None of the surgeries required conversion to laparotomy. The median patient age was 41.5 years (range,25-76). Eighteen patients had cervix cancer (5 stage IA2 and 13 stage IB1),and 2 had endometrial cancer (1 stage IB and 1 stage IIIA). Among those with cervix cancer,12 had adenocarcinoma,4 squamous cell carcinoma,and 2 adenosquamous carcinoma. The median weight was 70 kg (range,49-112). The median number of resected pelvic lymph nodes was 13 (range,9-26). One patient had nodal disease. The surgical margins were free of disease in all cases. The median blood loss was 200 ml (range,25-700 ml). Only 1 patient required an intraoperative blood transfusion (1 U packed red blood cells). The median length of hospital stay was 1 day (range,1-5). There were 3 short-term complications-unintentional cystotomy,pulmonary embolus,and pneumomediastinum with subcutaneous emphysema. There were 2 long-term complications-vaginal eviscerations and a lymphocyst. The median time to resumption of normal bladder function was 16 days (range,13-29). The median follow-up time was 8 months range (1-16). All patients remain free of disease at the time of this report. Conclusions.:Total laparoscopic radical hysterectomy can be performed safely with minimal blood loss and postoperative morbidity,and patients undergoing this proceduremay be discharged after an overnight stay in the hospital. | Ramirez P.T. Slomovitz B.M. Soliman P.T. 李欢 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，0，12： | 2 |
| 3 | 正常体重年轻妇女的子宫内膜癌显示文摘Objective. To determine if young, normal-weight women with endometrial cancer have unique risk factors and clinical characteristics when compared with young, overweight and obese women with endometrial cancer. Methods. Between 1989 and 2003, 1531 patients were treated for endometrial cancer. 188 (12%) of these women were premenopausal and under the age of 50 at time of diagnosis. The patients were divided into three groups based on body mass index (BMI): normal weight (BMI < 25 kg/m2), overweight (BMI 25-30 kg/m2) and obese (BMI ≥30 kg/m2). Clinical and pathologic characteristics were compared. Results. Of the 188 young endometrial cancer patients, 47 (25%) were of normal weight, 31 (17%) overweight and 106 (56%) obese. 4%of normalweight, 12%of overweight and 0%of obese patients met criteria for Lynch syndrome/hereditary non-polyposis colorectal cancer (HNPCC). Irregular menstrual cycles were reported by 30%normal-weight, 32%of overweight and 61%of obese women (P = 0.001). 17%of normal-weight, 7%of overweight and 14%of obese women had a history of infertility (P = 0.723). Nulliparity was noted in 57%of normal-weight, 47%of overweight and 57%of obese pa-tients (P = 0.583). Diabetes was reported in 4%of normal-weight, 13%of overweight and 35%of obese patients (P < 0.001). 28%of normal-weight, 26%of overweight and 14%of obese patients had synchronous primary tumors of the endometrium and ovary. Conclusions. As expected, a significantly higher proportion of obese and overweight women had diabetes and irregular menstrual cycles. Among the normal-weight women, a high proportion were nulliparous, had a history of infertility, irregular menstrual cycles and synchronous tumors of the endometrium and ovary when compared with the general population. This suggests that hormonal factors, and possibly polycystic ovarian syndrome (PCOS), may contribute to the development of endometrial cancer in young normalweight women. | Schmeler K.M. Soliman P.T. 朱晓明 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，0，2： | 0 |
| 4 | 同时发生的原发性子宫内膜癌与卵巢癌:84例单中心病例回顾 | Soliman P.T. Slomovitz B.M. Broaddus R.R. K.H. Lu 蔡国青 | 2005 | 世界核心医学期刊文摘(妇产科学分册)2005，0，1： | 0 |
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